ISDIN K-Ox Eyes for oily acne-prone skin

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical formulation containing hesperidin methyl chalcone inhibited skin oxidative stress, inflammation, and cytokine production induced by ultraviolet B irradiation in hairless mice.

  Photochemical & Photobiological Sciences, 2016

• A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.

  Journal of Cosmetic Dermatology, 2020

• Topical vitamin K oxide gel showed a non-significant trend toward faster resolution of pulsed dye laser-induced facial purpura compared to placebo in 20 subjects over a nine-day period.

  Journal of Drugs in Dermatology, 2009

• Topical application of a gel containing 2% phytonadione, 0.1% retinol, and 0.1% vitamins C and E reduced dark under-eye circles by decreasing haemostasis in 47% of 57 healthy Japanese adults and slightly decreased wrinkles after 8 weeks, while pigmentation was not clearly removed.

  Journal of Cosmetic Dermatology, 2004

• A new topical product containing retinol, alpha-hydroxy acids, arnica oil, ceramides, niacinamide, and phytonadione effectively treats actinic purpura by improving local circulation, thickening the skin, and repairing the skin barrier.

  The Journal of Clinical and Aesthetic Dermatology, 2017

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

  Experimental Dermatology, 2003

• Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

  Journal of Periodontology, 2009

• Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

  Journal of Cosmetic Dermatology, 2022

Why other eye cares fit oily acne-prone skin better

• Topical UP256 cream containing 0.5% bakuchiol administered twice daily significantly reduced inflammatory lesions and improved acne-related post-inflammatory hyperpigmentation in 13 subjects with mild or moderate facial acne.

  Journal of Drugs in Dermatology, 2021

• Topical combination of 5% sodium ascorbyl phosphate and 0.2% retinol reduced inflammatory acne lesions by 29.28% at 4 weeks and 63.10% at 8 weeks, outperforming either agent alone.

  International Journal of Cosmetic Science, 2009

• Sodium ascorbyl phosphate provides effective antimicrobial action, prevents sebum oxidation, and demonstrates superior clinical efficacy compared to a standard acne treatment in patients with acne vulgaris.

  International Journal of Cosmetic Science, 2005

Ingredients

Water, Glycerin, Isohexadecane, Isopropyl Myristate, Ppg-15 Stearyl Ether, Peg-30 Dipolyhydroxystearate, Phytonadione Epoxide, Magnesium Sulfate, Phenoxyethanol, Parfum, Microcristallina Cera Wax Microcrystalline Cera Wax, Ci 77891 Titanium Dioxide, Sodium Dextran Sulfate, Acrylates C12-22 Alkyl Methacrylate Copolymer, Steareth-20, Hesperidin Methyl Chalcone, Disodium Edta, Hydrolyzed Hyaluronic Acid, Ethylhexylglycerin, Peg-8, Pentylene Glycol, Tocopherol, Chlorhexidine Digluconate, N-Hydroxysuccinimide, Bht, Potassium Sorbate, Dipeptide-2, Ascorbyl Palmitate, Palmitoyl Tetrapeptide-7, Citric Acid, Ascorbic Acid, Chrysin, Palmitoyl Tripeptide-1, Sodium Citrate, Biotin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.