ISDIN and Trilogy are two celebrated skincare lines offering sophisticated moisturizers, gentle cleansers, advanced sunscreens, targeted serums, and soothing eye products. The Spanish brand suits sensitive skin and oily acne-prone skin best, featuring standout options like Fusion Water, Eryfotona Actinica, and K-Ox Eyes, whereas its counterpart caters to dry, balanced, and sensitive skin types through formulas such as the Vitamin C Ceramide Night Cream, Rosehip Cream Cleanser, and Line Smoothing Day Cream. While both rely on high-performing compositions to nurture a balanced, radiant complexion, they differ in their heritage and targeted concentrations, with the Puig-owned line focusing on meticulously engineered daily protection and specialized age or spot concerns.
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
This page compares some of the most popular ISDIN and Trilogy products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
“Nothing irritated my skin — Trilogy Line Smoothing Day Cream”
+Makeup performanceOften MentionedNot noted
“acts like a primer — ISDIN Eryfotona Actinica”
“My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
“Great under makeup — ISDIN Hyaluronic Concentrate”
–Fragrance and scent issuesOften MentionedSometimes Noted
“If you are sensitive to fragrances, you might find it irritating — Trilogy Rosehip Cream Cleanser”
“Scent is awful — Trilogy Line Smoothing Day Cream”
“smell is overpowering — ISDIN Eryfotona Actinica”
–High price point and valueOften MentionedRarely Noted
“Price to be high relative to performance — Trilogy Rosehip Cream Cleanser”
“very expensive — ISDIN Eryfotona Actinica”
–Too thick or heavyNot notedOften Mentioned
“A little bit too thick — Trilogy Vitamin C Ceramide Night Cream”
Questions and answers
ISDIN or Trilogy: which is better?
ISDIN and Trilogy each excel in different areas, with ISDIN offering lightweight sunscreens and sensitive skin care, while Trilogy provides deeply hydrating and brightening moisturizers. Reviewers note that ISDIN has a high price point, whereas Trilogy faces more complaints about product performance and formulation.
What is the difference between ISDIN and Trilogy?
ISDIN stands out for its ultralight, makeup-friendly sunscreens and sensitive skin formulas, whereas Trilogy is better known for hydrating and brightening moisturizers that offer deep moisture. However, the products on this page from Trilogy often face complaints regarding product performance and formulation, while ISDIN products are frequently noted for their high price point.
ISDIN or Trilogy: which moisturizer is better?
When it comes to moisturizers, Trilogy offers products on this page that are better known for hydration and deep moisture, whereas ISDIN is recognized for lightweight and non-greasy textures. For dry skin, Lovi rates the ISDIN Hyaluronic Concentrate as Average and the Trilogy Vitamin C Ceramide Night Cream as High.
Which is more affordable, ISDIN or Trilogy?
Trilogy tends to be more affordable, whereas reviewers often mention ISDIN for its high price point.
Which causes fewer breakouts, ISDIN or Trilogy?
ISDIN offers better options for breakout-prone skin, with products like Eryfotona Actinica earning a High Lovi fit level for acne-prone skin. Trilogy products on this page generally achieve an Average fit for acne-prone skin.
Which brand has more products that are fragrance-free, ISDIN or Trilogy?
ISDIN has more fragrance-free products on this page than Trilogy, offering three completely fragrance-free items compared to Trilogy's one. This means ISDIN provides a wider choice for shoppers looking to avoid added scents.
How do the founding years and corporate ownership of ISDIN and Trilogy compare?
ISDIN was founded in Spain in 1975 and is owned by Puig, whereas Trilogy was founded later in 2002 and is owned by CITIC Capital Holdings Limited.
Which brand offers better makeup-friendly sunscreens according to reviewers?
ISDIN offers better makeup-friendly sunscreens according to reviewers. The products on this page are mostly mentioned for being makeup-friendly and ultralight.
Ceramide iii · Skin Pharmacology and Physiology, 2026
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.