Clinique vs ISDIN
Clinique and ISDIN are established skincare houses originating in America and Spain respectively, offering cherished moisturizers, advanced sunscreens, and targeted serums driven by key ingredients like hyaluronic acid, glycerin, and caffeine. Both brands suit sensitive skin best, while the American line additionally comforts dry skin and the Spanish counterpart accommodates oily, acne-prone complexions. While the former relies on gentle formulations featuring barrier-restoring compounds, the latter utilizes meticulously engineered compositions to deliver a balanced, radiant look alongside daily protection.
Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..
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ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
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This page compares some of the most popular Clinique and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Clinique vs ISDIN products
People Say
Hydration, plumping, and smoothing effects Mostly MentionedMostly Mentioned
- “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+”
- “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
Lightweight and fast-absorbing texture Often MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “sinks in immediately — Clinique moisture surge”
Gentle, non-irritating, and sensitive skin friendly Mostly MentionedOften Mentioned
- “never irritated my eyes — Clinique All About Eyes”
- “No stinging eyes — Clinique Take The Day Off Cleansing Balm”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Good makeup base and compatibility Often MentionedOften Mentioned
- “Melts waterproof mascara — Clinique Take The Day Off Cleansing Balm”
- “foundation glides on — Clinique moisture surge”
- “acts like a primer — ISDIN Eryfotona Actinica”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Morning glow and radiance Rarely NotedOften Mentioned
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
- “skin looks immediately luminous — ISDIN K-Ox Eyes”
- “softening fine lines — ISDIN Retinal Intense Serum”
- “wake up glowing — Clinique Moisture Surge Overnight Mask”
Controls oil and mattifies Sometimes NotedSometimes Noted
- “keeps me matte — Clinique Dramatically Different Moisturizing Gel”
- “absorbs quickly — Clinique Moisture Surge Overnight Mask”
- “dries down matte — ISDIN Eryfotona Actinica”
- “Non-greasy — ISDIN Hyaluronic Moisture”
High price point and cost concerns Often MentionedOften Mentioned
- “jar is too small for the cost — Clinique moisture surge”
- “quite pricey — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- “very expensive — ISDIN Eryfotona Actinica”
- “My only wish is that ISDIN would make this product in a bigger size bottle. — ISDIN Fusion Water”
Unpleasant scent or strong fragrance Sometimes NotedOften Mentioned
- “Smells like nail polish remover — Clinique Clarifying Lotion 2”
- “Smells like old oil — Clinique Take The Day Off Cleansing Balm”
- “Has a weird plastic-like smell — Clinique Dramatically Different Moisturizing Lotion+”
- “smell is overpowering — ISDIN Eryfotona Actinica”
Causes breakouts or skin irritation Often MentionedRarely Noted
- “mild redness or irritation — ISDIN K-Ox Eyes”
- “I think the serum is too strong for my face as it has burned and left very rough and a peeling face. — ISDIN Flavo-C Serum”
- “slight peeling — ISDIN Retinal Intense Serum”
- “Woke up with whiteheads on my chin — Clinique Dramatically Different Moisturizing Lotion+”
Clinique vs ISDIN routines for dry skin
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
A$26.59
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Hydrating Toner
Pyunkang Yul Calming Deep Moisture Toner
Morning
A$23.99
-
Moisturizer
d'Alba First Spray Serum
Morning · Evening · Once a week
A$26.09
-
SPF
Bioderma Photoderm Mineral Fluide SPF50+
Morning
A$24.49
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
A$27.35
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
A$30.99
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
A$28.48
-
Cleanser
all about clean
Morning · Evening · Once a week
A$46.00
-
Hydrating Toner
Pyunkang Yul Calming Deep Moisture Toner
Morning
A$23.99
- Moisturizer moisture surge Morning · Evening · Once a week
-
SPF
Bioderma Photoderm Mineral Fluide SPF50+
Morning
A$24.49
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
A$56.98
-
Serum or Treatment
Smart Clinical Repair Wrinkle Correcting Serum
Evening · Once a week
A$149.95
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
A$28.48
Buy ISDIN routine · A$223.48 · 94% fit
Buy Clinique routine · A$365.39 · 75% fitSee multi-brand routine · 97% fit
Clinique vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
A$13.99
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
A$34.66
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
A$22.99
-
SPF
La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60
Morning
A$27.99
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
A$80.43
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
A$75.95
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
A$30.99
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
A$118.35
-
Cleanser
all about clean
Morning · Evening · Once a week
A$46.00
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
A$34.66
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
A$83.95
-
SPF
La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60
Morning
A$27.99
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
A$56.98
-
Cleansing Toner
Clarifying Lotion 2
Evening
A$87.00
- Serum or Treatment Even Better Clinical Dark Spot Corrector Evening · Once a week
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
A$118.35
Buy ISDIN routine · A$440.85 · 94% fit
Buy Clinique routine · A$490.43 · 75% fitSee multi-brand routine · 96% fit
Clinique vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
A$73.61
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
A$42.00
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
A$22.99
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
A$30.99
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
A$29.90
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
A$30.99
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
A$118.35
-
Cleanser
all about clean
Morning · Evening · Once a week
A$46.00
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
A$42.00
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
A$83.95
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
A$56.98
-
Cleansing Toner
Clarifying Lotion 2
Evening
A$87.00
- Serum or Treatment Even Better Clinical Dark Spot Corrector Evening · Once a week
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
A$118.35
Buy ISDIN routine · A$384.33 · 93% fit
Buy Clinique routine · A$469.78 · 72% fitSee multi-brand routine · 95% fit
Questions and answers
Clinique or ISDIN: which is better?
ISDIN is better than Clinique across most skin types on Lovi, offering superior routine fit for dry, oily, combination, sensitive, acne-prone, and mature skin. Reviewers note that ISDIN excels with ultralight sunscreens and a morning glow, while Clinique avoids fragrance in the products on this page.
What is the difference between Clinique and ISDIN?
Clinique is known for fragrance-free, hydrating moisturizers and gentle cleansers, whereas ISDIN is recognized for its ultralight and makeup-friendly sunscreens. Hyaluronic acid helps provide hydration for skin quality, and caffeine helps with cosmetic effects. Lovi indicates that ISDIN achieves a Superior routine fit across all skin types, while Clinique achieves a High fit for dry, sensitive, and dry sensitive skin.
Dermatologic Therapy, 2022Skin Pharmacology and Physiology, 2013
Clinique or ISDIN for dry skin?
For dry skin, ISDIN is a superior choice, featuring a Superior routine fit compared to Clinique's High fit on this page. Topical hyaluronic acid, a key ingredient found in the products on this page, helps improve skin quality and signs of aging.
Clinique or ISDIN: which moisturizer is better?
ISDIN is the better option for moisturizers because Lovi rates its routine fit for dry skin as Superior, while Clinique is High. Additionally, the products on this page for ISDIN help provide a lightweight texture.
Which is more affordable, Clinique or ISDIN?
Both Clinique and ISDIN share a high price point as a common drawback noted by reviewers, so neither brand is more affordable than the other.
Which brand has better fragrance-free options, Clinique or ISDIN?
Clinique has better fragrance-free options because every product on the Clinique page lists no fragrance in its ingredients, whereas several ISDIN products contain fragrance.
Which brand has a better routine fit for dry sensitive skin?
ISDIN has a better routine fit for dry sensitive skin, offering a Superior routine fit compared to Clinique's High fit on this page.
Clinique or ISDIN for oily skin?
For oily skin, Lovi rates Clinique as High and ISDIN as Superior. The products on this page help provide oil-controlling and mattifying effects while offering a lightweight texture.
Clinique or ISDIN for sensitive skin?
For sensitive skin, Lovi finds that Clinique has High routine fit and ISDIN has Superior routine fit. Every product on the Clinique page lists no fragrance, whereas several ISDIN products contain fragrance.
Clinique or ISDIN for acne-prone skin?
For acne-prone skin, Clinique and ISDIN both fit well, with Lovi routine fit rated as Average for Clinique and Superior for ISDIN. The products on this page help provide lightweight hydration and targeted treatments, though ISDIN offers an advantage in lightweight textures while Clinique avoids added fragrance.
Clinique or ISDIN for mature skin?
For mature skin, Lovi rates ISDIN as Superior and Clinique as Average. The products on this page help provide anti-aging and brightening effects with ingredients like vitamin C.
Research behind their key ingredients
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Algae extract protection effect on oxidized protein level in human stratum corneum
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Functional properties and skin care effects of sodium trehalose sulfate
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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