Medicube vs ISDIN
Medicube and ISDIN are well-regarded international skincare companies that offer carefully formulated products for various skin types. The Korean brand founded in 2016 features moisturizers, serums, toners, and masks with niacinamide, collagen, and hyaluronic acid to suit dry and oily acne-prone skin, while the Spanish brand established in 1975 provides elegant moisturizers, advanced sunscreens, restorative serums, and eye products that suit dry and sensitive skin best. While both lines use thoughtfully balanced formulas to address concerns like dark spots, acne, and aging, the former focuses on profound results through active ingredients, and the latter delivers gentle daily comfort and dependable protection.
Medicube is a Korean skincare brand founded in 2016 and owned by APR Corp..
medicubereviews.co.ukglossy.co
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
puig.combeautymatter.comuploads.puig.com
This page compares some of the most popular Medicube and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Medicube vs ISDIN products
People Say
Hydration and Moisture Mostly MentionedMostly Mentioned
- “skin feels bouncier and hydrated — Medicube PDRN Pink Peptide Serum”
- “glass skin — Medicube PDRN Pink Collagen Gel Mask”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Lightweight and Non-Greasy Texture Not notedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
Skin Texture and Smoothing Often MentionedOften Mentioned
- “gives my skin a smooth, glass-like finish — Medicube Zero Pore Pad”
- “skin feels smoother — Medicube PDRN Pink Peptide Serum”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
Glow and Brightening Often MentionedSometimes Noted
- “gave me instant glass skin — Medicube Collagen Jelly Cream”
- “woke up with glowing skin — Medicube Collagen Night Wrapping Mask”
- “Dark spots go away faster — Medicube Deep Vita C Pad”
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
Acne and Pore Care Often MentionedNot noted
- “Pores drastically reduced — Medicube Zero Foam Cleanser”
- “Removes every trace of oil — Medicube Red Foam Cleanser”
- “noticed a real difference in pore visibility — Medicube Zero Pore Pad”
High Price Point Sometimes NotedOften Mentioned
- “tube is tiny for the price — Medicube Collagen Night Wrapping Mask”
- “price is steep — Medicube PDRN Pink Collagen Gel Mask”
- “price is a bit steep — Medicube Red Succinic Acid Peeling Pad”
- “very expensive — ISDIN Eryfotona Actinica”
Strong Fragrance and Scent Often MentionedOften Mentioned
- “slightly fishy smell — Medicube PDRN Pink Peptide Serum”
- “smells like old lady perfume — Medicube Collagen Jelly Cream”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and Application Issues Sometimes NotedSometimes Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “Pilled up on my skin — ISDIN Hyaluronic Moisture”
- “messy — Medicube PDRN Pink Collagen Gel Mask”
Medicube vs ISDIN routines for dry skin
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Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
S$25.06
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Hydrating Toner
COSRX Propolis Synergy Toner
Morning
S$41.07
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Moisturizer
d'Alba First Spray Serum
Morning · Evening · Once a week
S$25.94
-
SPF
Eryfotona Actinica
Morning
S$110.01
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
S$39.68
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Serum or Treatment
Flavo-C Serum
Evening · Once a week
S$161.49
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Nourishing Mask
MEDIHEAL Collagen Essential Mask
Once a week
S$62.94
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Cleanser
Zero Foam Cleanser
Morning · Evening · Once a week
S$25.74
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Hydrating Toner
Triple Collagen Toner
Morning
S$41.00
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Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
S$28.12
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SPF
thinkbaby Safe Sunscreen SPF 50+
Morning
S$21.09
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
S$39.68
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Serum or Treatment
One Day Exosome Shot 2000
Evening · Once a week
S$30.69
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Nourishing Mask
Deep Peptide Radiance Mask
Once a week
S$3.85
Buy ISDIN routine · S$466.19 · 93% fit
Buy Medicube routine · S$127.51 · 91% fitSee multi-brand routine · 99% fit
Medicube vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
S$30.40
-
Hydrating Toner
TROIAREUKE H+Cocktail Purifying Ampoule Toner
Morning · Once a week
S$168.51
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Moisturizer
SKIN1004 Centella Cream
Morning · Evening · Once a week
S$33.87
-
SPF
Eryfotona Actinica
Morning
S$110.01
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Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
S$70.21
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Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening · Once a week
S$36.48
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Serum or Treatment
Flavo-C Serum
Evening · Once a week
S$161.49
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Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
S$89.14
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Cleanser
Red Foam Cleanser
Morning · Evening · Once a week
S$47.21
-
Hydrating Toner
Triple Collagen Toner
Morning · Once a week
S$41.00
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
S$28.12
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
S$28.72
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
S$70.21
-
Cleansing Toner
Zero Pore Pad
Evening · Once a week
S$36.48
-
Cleansing Mask
Zero Pore Blackhead Mud Mask
Once a week
S$25.68
Buy ISDIN routine · S$700.11 · 91% fit
Buy Medicube routine · S$223.62 · 87% fitSee multi-brand routine · 96% fit
Medicube vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
S$30.00
-
Hydrating Toner
Whamisa Organic Flowers Toner Deep Rich
Morning · Once a week
S$64.81
-
SPF
Eryfotona Actinica
Morning
S$110.01
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
S$70.21
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening · Once a week
S$36.48
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
S$161.49
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
S$89.14
-
Cleanser
Red Foam Cleanser
Morning · Evening · Once a week
S$47.21
-
Hydrating Toner
Triple Collagen Toner
Morning · Once a week
S$41.00
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
S$28.12
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
S$28.72
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
S$70.21
-
Cleansing Toner
Zero Pore Pad
Evening · Once a week
S$36.48
-
Cleansing Mask
Zero Pore Blackhead Mud Mask
Once a week
S$25.68
Buy ISDIN routine · S$562.14 · 92% fit
Buy Medicube routine · S$223.62 · 87% fitSee multi-brand routine · 97% fit
Questions and answers
Medicube or ISDIN: which is better?
Both brands offer strong options, but ISDIN holds a Superior routine fit across nearly all skin types compared to Medicube's High level. Medicube stands out for glow and pore care, while ISDIN is recognized for its ultralight sunscreens and lightweight moisturizers.
What is the difference between Medicube and ISDIN?
Medicube is a South Korean skincare brand that helps with acne and pore care and glow and brightening, while ISDIN is a Spanish brand that provides lightweight and non-greasy textures. Both brands offer a superior routine fit for dry skin, but ISDIN has a superior fit for most other skin types on this page.
Medicube or ISDIN for dry skin?
Both Medicube and ISDIN fit dry skin well, with Lovi giving Medicube a Superior fit level and ISDIN a Superior fit level. Topical hyaluronic acid helps improve skin quality and signs of aging.
Medicube or ISDIN: which moisturizer is better?
Both brands offer effective moisturizers, but Medicube is a better fit if you want deep hydration and a radiant glow, while ISDIN specializes in ultralight, lightweight formulas. Medicube features popular moisturizers like the Collagen Jelly Cream and AGE-R Booster Gel, whereas ISDIN offers options such as the Hyaluronic Concentrate and Hyaluronic Moisture.
Which is more affordable, Medicube or ISDIN?
Medicube is generally more affordable, though reviews for both brands frequently mention high price points.
Medicube or ISDIN: which brand is better for glowing and brightening?
Medicube is better for glowing and brightening, as review themes show that it does better in this category. Additionally, niacinamide helps reduce cutaneous pigmentation and suppress melanosome transfer.
Which brand has more fragrance-free products, Medicube or ISDIN?
Medicube has more fragrance-free products on this page than ISDIN, as 23 of its 25 products list no fragrance compared to only 3 of the 8 ISDIN products.
Medicube or ISDIN: which brand is older and where was it founded?
ISDIN is the older brand, having been founded in Spain in 1975, whereas Medicube was founded in South Korea in 2016.
Medicube or ISDIN for oily skin?
ISDIN has a Superior Lovi fit for oily skin, whereas Medicube has a High fit. ISDIN reviewers mostly mention ultralight, lightweight, and makeup-friendly sunscreens, while Medicube is known for deep hydration moisturizers.
Medicube or ISDIN for sensitive skin?
Both brands offer solid options for sensitive skin, but Lovi rates ISDIN as Superior and Medicube as High for this skin type. Reviewers note that ISDIN shines with ultralight and skin-friendly sunscreens, while Medicube provides soothing and gentle choices.
Medicube or ISDIN for acne-prone skin?
Both Medicube and ISDIN are good options for acne-prone skin, with Lovi rating ISDIN as Superior and Medicube as High. Reviewers note that Medicube does better for acne and pore care, while most of the products on this page from Medicube list no fragrance.
Research behind their key ingredients
Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Effect of Camellia japonica oil on human type I procollagen production and skin barrier function
Protective effects of Camellia japonica flower extract against urban air pollutants
Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Functional properties and skin care effects of sodium trehalose sulfate
Composition characterization and clinical efficacy study of a salmon egg extract
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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