Medicube vs ISDIN
Medicube and ISDIN are well-regarded international skincare companies that offer carefully formulated products for various skin types. The Korean brand founded in 2016 features moisturizers, serums, toners, and masks with niacinamide, collagen, and hyaluronic acid to suit dry and oily acne-prone skin, while the Spanish brand established in 1975 provides elegant moisturizers, advanced sunscreens, restorative serums, and eye products that suit dry and sensitive skin best. While both lines use thoughtfully balanced formulas to address concerns like dark spots, acne, and aging, the former focuses on profound results through active ingredients, and the latter delivers gentle daily comfort and dependable protection.
Medicube is a Korean skincare brand founded in 2016 and owned by APR Corp..
medicubereviews.co.ukglossy.co
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
puig.combeautymatter.comuploads.puig.com
This page compares some of the most popular Medicube and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Medicube vs ISDIN products
People Say
Hydration and Moisture Mostly MentionedMostly Mentioned
- “skin feels bouncier and hydrated — Medicube PDRN Pink Peptide Serum”
- “glass skin — Medicube PDRN Pink Collagen Gel Mask”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Lightweight and Non-Greasy Texture Not notedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
Skin Texture and Smoothing Often MentionedOften Mentioned
- “gives my skin a smooth, glass-like finish — Medicube Zero Pore Pad”
- “skin feels smoother — Medicube PDRN Pink Peptide Serum”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
Glow and Brightening Often MentionedSometimes Noted
- “gave me instant glass skin — Medicube Collagen Jelly Cream”
- “woke up with glowing skin — Medicube Collagen Night Wrapping Mask”
- “Dark spots go away faster — Medicube Deep Vita C Pad”
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
Acne and Pore Care Often MentionedNot noted
- “Pores drastically reduced — Medicube Zero Foam Cleanser”
- “Removes every trace of oil — Medicube Red Foam Cleanser”
- “noticed a real difference in pore visibility — Medicube Zero Pore Pad”
High Price Point Sometimes NotedOften Mentioned
- “tube is tiny for the price — Medicube Collagen Night Wrapping Mask”
- “price is steep — Medicube PDRN Pink Collagen Gel Mask”
- “price is a bit steep — Medicube Red Succinic Acid Peeling Pad”
- “very expensive — ISDIN Eryfotona Actinica”
Strong Fragrance and Scent Often MentionedOften Mentioned
- “slightly fishy smell — Medicube PDRN Pink Peptide Serum”
- “smells like old lady perfume — Medicube Collagen Jelly Cream”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and Application Issues Sometimes NotedSometimes Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “Pilled up on my skin — ISDIN Hyaluronic Moisture”
- “messy — Medicube PDRN Pink Collagen Gel Mask”
Medicube vs ISDIN routines for dry skin
-
Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
CA$20.19
-
Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
CA$27.99
-
Moisturizer
Tata Harper Repairative Moisturizer
Morning · Evening · Once a week
CA$162.00
-
SPF
Fusion Water
Morning
CA$69.99
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
CA$17.99
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
CA$65.00
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
CA$29.99
-
Cleanser
Zero Foam Cleanser
Morning · Evening · Once a week
CA$22.31
-
Hydrating Toner
Triple Collagen Toner
Morning
CA$23.45
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
CA$25.23
-
SPF
d'Alba Piedmont Waterfull Mild Sunscreen
Morning
CA$38.00
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
CA$17.99
-
Serum or Treatment
One Day Exosome Shot 2000
Evening · Once a week
CA$28.49
-
Nourishing Mask
Deep Peptide Radiance Mask
Once a week
CA$18.35
Buy ISDIN routine · CA$393.15 · 94% fit
Buy Medicube routine · CA$173.82 · 91% fitSee multi-brand routine · 99% fit
Medicube vs ISDIN routines for oily skin
-
Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
CA$20.96
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
CA$37.60
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
CA$29.98
-
SPF
Fusion Water
Morning
CA$69.99
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
CA$23.99
-
Cleansing Toner
Pixi Glow Tonic
Evening
CA$28.90
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
CA$65.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
CA$29.50
-
Cleansing Mask
Tatcha The Clarifying Clay Mask
Once a week
CA$95.00
-
Cleanser
Red Foam Cleanser
Morning · Evening · Once a week
CA$25.50
-
Hydrating Toner
Triple Collagen Toner
Morning · Once a week
CA$23.45
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
CA$25.23
-
SPF
La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60
Morning
CA$35.95
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
CA$23.99
-
Cleansing Toner
Zero Pore Pad
Evening
CA$33.99
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
CA$29.50
-
Cleansing Mask
Zero Pore Blackhead Mud Mask
Once a week
CA$26.29
Buy ISDIN routine · CA$400.92 · 91% fit
Buy Medicube routine · CA$223.90 · 88% fitSee multi-brand routine · 96% fit
Medicube vs ISDIN routines for combination skin
-
Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
CA$44.95
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
CA$37.60
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
CA$29.98
-
SPF
Fusion Water
Morning
CA$69.99
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
CA$23.99
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
CA$31.99
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
CA$65.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
CA$29.50
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
CA$50.00
-
Cleanser
Red Foam Cleanser
Morning · Evening · Once a week
CA$25.50
-
Hydrating Toner
Triple Collagen Toner
Morning · Once a week
CA$23.45
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
CA$25.23
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
CA$20.96
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
CA$23.99
-
Cleansing Toner
Zero Pore Pad
Evening
CA$33.99
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
CA$29.50
-
Cleansing Mask
Zero Pore Blackhead Mud Mask
Once a week
CA$26.29
Buy ISDIN routine · CA$383.00 · 92% fit
Buy Medicube routine · CA$208.91 · 88% fitSee multi-brand routine · 96% fit
Questions and answers
Medicube or ISDIN: which is better?
ISDIN has a Superior Lovi fit across nearly all skin types, making it the better overall choice for most users compared to Medicube. ISDIN also excels in lightweight texture, whereas Medicube is noted for glow and pore care.
What is the difference between Medicube and ISDIN?
Medicube tends to focus on hydration and brightening with a lower price point, while ISDIN is known for ultralight, skin-friendly sunscreens that may suit sensitive skin well. The products on this page show that both brands offer strong options for dry skin, though ISDIN achieves a Superior routine fit across a wider variety of skin types.
Medicube or ISDIN for dry skin?
Both Medicube and ISDIN fit dry skin well, with Lovi rating Medicube's routine as Superior and ISDIN's routine as Superior. Medicube's products on this page help provide deep hydration and a radiant glow, while ISDIN is mostly noted for ultralight, lightweight moisturizers and sunscreens.
Dermatologic Therapy, 2022Dermatology Practical & Conceptual, 2022
Medicube or ISDIN: which moisturizer is better?
Both brands offer moisturizers, but Medicube is especially known for deep hydration moisturizers and a radiant glow, whereas ISDIN is noted for lightweight moisturizers. Topical hyaluronic acid helps improve skin quality and signs of skin aging.
Which is more affordable, Medicube or ISDIN?
Medicube is more affordable, though reviews for both brands frequently mention a high price point. Review themes indicate that high price is a noted drawback specifically for Medicube.
Medicube or ISDIN for a lightweight and non-greasy texture?
ISDIN is the better choice for a lightweight and non-greasy texture, as the products on this page are mostly noted for their ultralight sunscreens and lightweight moisturizers. Medicube, meanwhile, is more often mentioned by reviewers for causing a sticky residue.
Medicube or ISDIN for oily skin?
Both brands fit oily skin well, but ISDIN has a Superior fit level on Lovi compared to Medicube's High fit level. ISDIN is especially known for ultralight, makeup-friendly sunscreens, while Medicube offers stronger options for glow and pore care.
Medicube or ISDIN for sensitive skin?
Both Medicube and ISDIN fit sensitive skin, with Lovi giving Medicube a High fit level and ISDIN a Superior fit level. The products on this page for both brands mostly feature lightweight hydration and soothing properties.
Medicube or ISDIN for acne-prone skin?
Both Medicube and ISDIN are good options for acne-prone skin, with Lovi rating Medicube as High and ISDIN as Superior for this skin type. Medicube features products on this page like the Zero Pore Pad that are well-suited for acne and pore care, while ISDIN offers ultralight sunscreens and moisturizers that help maintain clear skin.
Medicube or ISDIN for mature skin?
Both Medicube and ISDIN fit mature skin at a High level on Lovi. Medicube offers dedicated targeted care like the Deep Lifting Peptide Eye Cream which has a Superior fit for mature skin. ISDIN helps protect and nourish mature skin with sunscreens and serums like Eryfotona Actinica, which also has a Superior fit for mature skin.
The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007
Medicube or ISDIN for skin with dark spots?
Both Medicube and ISDIN fit skin with dark spots at a High level. Niacinamide helps reduce skin pigmentation.
Research behind their key ingredients
Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Effect of Camellia japonica oil on human type I procollagen production and skin barrier function
Protective effects of Camellia japonica flower extract against urban air pollutants
Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Functional properties and skin care effects of sodium trehalose sulfate
Composition characterization and clinical efficacy study of a salmon egg extract
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-

Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.
























































