Avène Cicalfate+ Restorative Protective Cream for mature skin

Avène Thermal Spring Water
Zinc Oxide
Glycerin
Caprylic Capric Triglyceride
Beeswax
Average
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
Works for mature skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Suitable for normal skin, this product offers moderate moisturizing and barrier repair due to glycerin and zinc oxide, which hydrate and protect your skin. While beneficial for general skincare, these ingredients are not specifically targeted for your wrinkles and fine lines.
- The presence of caprylic capric triglyceride further supports your skin hydration and barrier function, aligning well with your normal skin type.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
People Say
★4.1Overall rating based on 15.7k+ reviewsIt is also praised for its versatility in healing various skin concerns and its rich, protective texture. However, a significant number of recent reviews mention issues with the product separating into oil and water, and some users with oily or acne-prone skin report clogged pores.
Highlights
Soothes irritation Mostly Mentioned
- “Calmed my angry red skin overnight”
- “The only thing that doesn't sting my sensitive face”
- “Took the heat out of my sunburn.”
Repairs skin barrier Often Mentioned
- “Healed my over-exfoliated skin in days”
- “Saved my barrier after a bad reaction”
- “Restored my skin texture completely”
- “Magic for dry, cracking patches.”
Rich texture Often Mentioned
- “Thick but absorbs well eventually”
- “Creates a perfect seal for the night”
- “Love using this for slugging in winter”
- “Feels like a protective blanket on my face.”
Product separation Often Mentioned
- “Tube squirted water everywhere”
- “Separates into oil and solid chunks”
- “Have to shake it violently every time”
- “A watery mess despite being new.”
Versatile healing Sometimes Noted
- “Used it on my stitches and they healed beautifully”
- “Great for my baby's diaper rash”
- “Healed my chemical peel peeling faster”
- “Put it on a kitchen burn and it didn't blister.”
Causes breakouts Sometimes Noted
- “Woke up with tiny whiteheads all over”
- “Too heavy, caused deep cystic acne”
- “Triggered a bad breakout on my chin”
- “Not safe for fungal acne.”
Leaves white cast Sometimes Noted
- “Leaves a ghost-like cast”
- “Takes forever to rub in”
- “Looked pale and chalky after applying”
- “Can't wear this during the day due to the white cast.”
Packaging issues Rarely Noted
- “Tube cracked on the side”
- “Impossible to get the last bit out”
- “Metal tube splits and leaks product”
- “Cap broke off easily.”
Sources: lovi.care, amazon.com, aveneusa.com, dermstore.com, lovelyskin.com, ulta.com, and more
Questions and answers
How well does Avène Cicalfate+ Cream work for mature skin?
This cream works moderately well for mature skin by providing basic hydration and barrier protection with glycerin and zinc oxide, though it lacks specific ingredients for wrinkles and fine lines. To truly fit mature skin, a product of this type needs potent ingredients that address wrinkles and fine lines, along with a rich blend of hydrating components, peptides, and antioxidants.
Which ingredients make this cream a good fit for mature skin?
Glycerin, zinc oxide, and caprylic capric triglyceride help hydrate and protect your skin, though this cream lacks ingredients that specifically target wrinkles and fine lines. To better fit mature skin, a product of this type needs peptides, antioxidants, and potent ingredients that effectively address lines while maintaining the moisture balance.
Clinical, Cosmetic and Investigational Dermatology, 2017Life, 2023
What does Avène Thermal Spring Water do for mature skin?
Avène Thermal Spring Water helps soothe and calm mature skin while supporting comfort during treatments. It is unlikely to alter skin elasticity or tightness, so a complete routine for mature skin also needs nourishing oils and anti-aging ingredients like retinol or peptides to smooth lines and keep skin soft.
Journal of Cosmetic Dermatology, 2007Experimental Dermatology, 2024
What does Zinc Oxide do for mature skin?
Zinc oxide helps protect mature skin from UV damage and may reduce skin roughness and wrinkle depth when combined with antioxidants. This type of product needs ingredients like hyaluronic acid and soothing minerals to keep dry or thinning skin feeling smooth and calm.
Where does this cream go in a skincare routine for mature skin?
This cream goes as the moisturizer step in your evening routine, and may also be used in the morning if you need extra moisture. It is unlikely to cause irritation because it lacks harsh ingredients, but mature skin also needs targeted ingredients like retinoids or antioxidants to address fine lines and wrinkles.
The Journal of Dermatological Treatment, 2022Clinical, Cosmetic and Investigational Dermatology, 2017
Can I use this cream with retinol, and in what order?
You can use this cream with retinol by applying your retinol first and following with the cream to keep your skin calm and hydrated. Barrier-supporting moisturizers like this one help your skin adjust to retinoids while keeping irritation low, making it a safe addition to your routine. To better care for mature skin, a product of this type needs added ingredients that specifically target fine lines and wrinkles.
How often should I use this cream?
You can use this moisturizing treatment twice daily as part of your routine. Daily application helps keep your skin hydrated and protected, though mature skin also needs targeted ingredients for wrinkles and fine lines.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this cream clog pores, cause breakouts or purging for mature skin?
This cream may cause breakouts for mature skin, as reviewers moderately complain about this issue. However, it has very safe ingredients with no harsh additives, so it is unlikely to cause irritation.
Can I use this cream around the eyes or on my body?
You can use this cream on your body and around your eyes because it is very safe and unlikely to irritate your skin. Mature skin needs products with targeted anti-aging ingredients like hyaluronic acid, peptides, and botanical extracts to smooth fine lines and wrinkles in these areas.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical application of an emollient emulsion containing 15.0% caprylic/capric triglyceride doubled the amount of urocanic acid isomers and increased skin hydration with reduced transepidermal water loss in healthy subjects, though it did not prevent ultraviolet-induced urocanic acid isomerization.
Life, 2023Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes.
Life, 2023Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne.
The Medical Journal of Malaysia, 2024A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro.
International Journal of Cosmetic Science, 2025Topical 0.5% hyaluronic-ZnO nanogel applied twice daily reduced inflammatory-lesion counts by 58% at week four in human subjects compared to baseline without causing erythema.
Biomedicines, 2025Nels cream achieved a similar reduction in inflammatory and noninflammatory lesion counts compared to 5% benzoyl peroxide in acne vulgaris patients, but caused significantly fewer side-effects such as peeling and dryness.
Clinical and Experimental Dermatology, 2000Topically applied coated and uncoated zinc oxide nanoparticles under flexing and massage are retained in the stratum corneum with no significant penetration into the viable epidermis and no cellular toxicity in human skin.
Nanomedicine, 2016The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Topical application of a honey, olive oil, and beeswax mixture three times daily for up to 4 weeks resulted in clinical responses in 86% of patients with pityriasis versicolor, 78% with tinea cruris, and 75% with tinea corporis.
Complementary Therapies in Medicine, 2004A prototype body cream containing bee venom, propolis, honey, beeswax, and royal jelly demonstrated stability for 90 days, high antioxidant capacity of 85.45%, lack of cytotoxicity with over 70% cell viability, and no irritation or allergic reaction in dermatological analysis, while improving skin parameters in a panel test.
Journal of Cosmetic Dermatology, 2022MUD1 protected human dermal fibroblasts against AAPH-induced oxidative stress by increasing cell viability, reducing oxidative damage, improving mitochondrial functionality, and enhancing wound healing capacities.
International Journal of Molecular Sciences, 2018
Why other moisturizers fit mature skin better
Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.
International Journal of Medical Sciences, 2021Nanoemulsions containing Macadamia integrifolia seed oil successfully enhanced skin hydration and reduced wrinkles in human volunteers, outperforming conventional emulsions in skin hydration enhancement.
Nanomaterials, 2024Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026
Ingredients
Avene Thermal Spring Water Avene Aqua Avene Aqua, Caprylic Capric Triglyceride, Paraffinum Liquidum Mineral Oil, Glycerin, Hydrogenated Oil, Zinc Oxide, Propylene Glycol, Polyglyceryl-2 Sesquiisostearate, Peg-22 Dodecyl Glycol Copolymer, Aluminum Stearate, Aquaphilus Dolomiae Ferment Filtrate, Arginine, Beeswax Cera Alba Cera, Copper Sulfate, Magnesium Stearate, Magnesium Sulfate, Microcrystalline Wax Cera Microcristallina Wax Cera, Tromethamine, Zinc Sulfate
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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