Anua Niacinamide 10% + TXA 4% Serum for sensitive skin
Niacinamide
Txa Tranexamic Acid
Hyaluronic Acid
Panthenol
AllantoinAverage
- HighNormal Skin Fit
- AverageEffectiveness
- Low RiskSafety
Works for sensitive skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate brightening and evening of skin tone, which is supportive for your redness and irritation, due to the presence of niacinamide and tranexamic acid in moderate concentrations.
- The inclusion of panthenol and allantoin provides mild soothing effects, and the formula is highly suitable for normal skin due to niacinamide and glycerin offering good humectant action and barrier repair.
- The product is generally safe for your sensitive skin, with a low risk of irritation due to the absence of harsh ingredients.
How to apply
- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
People Say
★4.6Overall rating based on 2.5k+ reviewsBased on a very large amount of data, this serum is highly effective at fading post-acne marks and evening out skin tone, with many users reporting a radiant glow within weeks. While generally well-tolerated and hydrating for many, a significant number of users find the serum leaves a sticky residue, and a smaller portion experience breakouts or irritation, possibly due to the high niacinamide concentration.
Highlights
Fades dark spots Mostly Mentioned
- “Significant reduction in hyperpigmentation from acne scarring.”
- “Fades my dark spots so well... noticed a brightening effect within two-three weeks.”
- “Helped fade my postpartum spots!”
- “Getting rid of acne marks on my face.”
Brightens skin Often Mentioned
- “Gives my skin a beautiful, healthy glow.”
- “My face visibly brighten[ed].”
- “Skin looks healthier and brighter.”
- “Wake up to a brighter skin.”
Sticky finish Often Mentioned
- “Left such a gross tacky finish that refused to dry.”
- “Serum is so sticky... even if I use a tiny drop.”
- “Feels sticky to me.”
- “Has a slightly tacky finish to it.”
Hydrating Sometimes Noted
- “Sinks right into my skin.”
- “Feels quite hydrating... tightness disappears.”
- “Doesn't clash with other parts of my routine.”
- “Leaves skin silky-smooth.”
Improves texture Sometimes Noted
- “Reduction in texture from acne scarring.”
- “Skin feels plump and bouncy.”
- “Smoothing out small bumps.”
- “Pore minimization, skin tightening.”
Caused breakouts Sometimes Noted
- “Broke me out.”
- “My forehead is full [of] acne.”
- “Caused tiny bumps/whiteheads.”
- “Started getting acne... not sure if it's because of this.”
Caused irritation Rarely Noted
- “Irritated my skin at first.”
- “Might be irritating to some skin types.”
- “Stinging sensation upon application.”
- “Too strong for sensitive skin.”
Slow results Rarely Noted
- “Did nothing for my skin.”
- “Haven't noticed much of a difference.”
- “Not as fast as [I] want it to be.”
- “Saw very minimal results.”
Sources: lovi.care, oliveyoung.com, yesstyle.com, stylevana.com, reddit.com, skinsort.com, and more
Questions and answers
How well does Anua Niacinamide 10% + TXA 4% Serum work for sensitive skin?
This serum works for sensitive skin, though other products fit it better. It helps calm redness and even out skin tone with a low risk of irritation, but a product for this skin needs stronger soothing and skin-repairing ingredients without harsh additives to deliver optimal results.
American Journal of Clinical Dermatology, 2002The British Journal of Dermatology, 2002
Which ingredients make this serum a good fit for sensitive skin?
Niacinamide and tranexamic acid help even out skin tone and calm redness, while panthenol and allantoin provide mild soothing effects for sensitive skin. This serum works for your skin, though products rated higher for sensitive skin need extra antioxidants and deeply calming ingredients that soothe irritation without any risk.
The British Journal of Dermatology, 2002American Journal of Clinical Dermatology, 2002
What does Niacinamide do for sensitive skin?
Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
What does Tranexamic Acid do for sensitive skin?
Tranexamic acid helps calm sensitive skin by strengthening the skin barrier and reducing redness and flushing. It is unlikely to cause severe reactions, making it a well-tolerated choice for reactive or easily irritated skin.
International Journal of Dermatology, 2014Clinical, Cosmetic and Investigational Dermatology, 2024
Where does this serum go in a skincare routine for sensitive skin?
This serum goes in the evening routine after your cleansing and soothing toner, followed by a moisturizer. Sensitive skin works best with treatment products that include soothing ingredients like panthenol and allantoin alongside gentle brighteners to calm redness and irritation.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying the serum first to help calm your skin, followed by your retinol. This product is generally safe with a low risk of irritation for your sensitive skin, but a product for this skin needs extra soothing and barrier-repairing ingredients like panthenol and allantoin to prevent dryness.
How often should I use this serum?
This serum is used in the evening once a week for sensitive skin, and people who tolerate it well may carefully use it more often. To work best for this skin type, a product needs soothing ingredients like panthenol and allantoin to keep it calm and comfortable.
Can this serum clog pores, cause breakouts or purging for sensitive skin?
This serum may cause breakouts for some people with sensitive skin, as reviewers moderately complain about this issue. To better prevent clogged pores and breakouts, sensitive skin needs a lightweight, non-greasy formula with gentle soothing ingredients and without heavy sticky agents.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.
The British Journal of Dermatology, 2002Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment.
Journal of Cosmetic Dermatology, 2025Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.
Auris, Nasus, Larynx, 2020Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018
Ingredients
Water, Niacinamide, Glycerin, Butylene Glycol, 1,2-Hexanediol, Betaine, Panthenol, Hyaluronic Acid, Allantoin, Tocopherol, Ethylhexylglycerin, Xanthan Gum, Disodium Edta
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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