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Pixi vs Sesderma

Pixi and Sesderma are distinguished skincare brands founded in 1999 and 1989, respectively, offering thoughtful formulas designed to refine the complexion. Pixi is universally loved for its nourishing toners, targeted serums, soothing eye products, and hydrating moisturizers, while Sesderma is beloved for its advanced serums and meticulously engineered formulas. The former brand suits sensitive skin and oily skin best, featuring solutions like the Glow Tonic for acne-prone skin, the Glow Peel Pads for skin with dark spots, and the Retinol Tonic for mature skin, whereas the latter brand suits sensitive, hyperpigmented, and aging skin types best, highlighting standout options such as the Azelac RU Serum for acne-prone skin. While both rely on gentle, balancing natures or synergistic active compounds to maintain a healthy appearance, they differ through their distinct British and Spanish heritage.

Pixi is a British skincare brand founded in 1999.

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Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

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This page compares some of the most popular Pixi and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Questions and answers

Pixi or Sesderma: which is better?

Pixi is better suited for a wider variety of skin types on this page, as Lovi rates its products with a Superior fit for sensitive, oily, and acne-prone skin, whereas Sesderma features only one product.

What is the difference between Pixi and Sesderma?

Pixi offers a much larger variety of products on this page than Sesderma, and Lovi rates Pixi best for sensitive, oily, and acne-prone skin. Aloe vera helps soothe skin irritation, while hyaluronic acid provides deep hydration.

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Which is more affordable, Pixi or Sesderma?

This page does not provide pricing information to compare the affordability of Pixi and Sesderma.

Which causes fewer breakouts, Pixi or Sesderma?

Pixi fits acne-prone skin best with superior options like Retinol Tonic, whereas Sesderma offers Azelac RU Serum with a high fit level for acne-prone skin. Aloe vera in Pixi products helps soothe skin and may prevent irritation.

Iranian Journal of Medical Sciences, 2019

How does the founding year and country of origin compare between Pixi and Sesderma?

Pixi was founded in 1999 in the United Kingdom, whereas Sesderma was founded a decade earlier in 1989 in Spain.

Which Pixi products are fragrance-free compared to Sesderma's Azelac RU Serum?

On this page, 7 of the 10 Pixi products list no fragrance, whereas Sesderma's Azelac RU Serum contains fragrance. Lovi finds that the fragrance-free Pixi products include options like Glow Peel Pads and Vitamin-C Serum.

What are the main skin types that Pixi brand-focused routines fit best?

The products on this page for Pixi fit sensitive skin, oily skin, and acne-prone skin best according to the brand-focused routines.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.