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Pixi vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Pixi and Sesderma are distinguished skincare brands that bring purposeful formulations to daily routines. The British brand founded in 1999 offers gentle toners, serums, eye products, and moisturizers that suit oily and sensitive skin best, featuring standout solutions like the Glow Tonic for acne-prone skin, the Glow Peel Pads for dark spots, and the Retinol Tonic for mature skin. Conversely, the Spanish brand founded in 1989 specializes in advanced serums for sensitive, hyperpigmented, and aging skin, utilizing botanical extracts and active compounds such as the Azelac RU Serum for acne-prone skin. While both deliver radiant complexions, they differ through the British line focusing on balanced, everyday care and the latter employing meticulously engineered compounds to refine skin texture.

Pixi is a British skincare brand founded in 1999.

pixibeauty.comtracxn.compitchbook.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Pixi and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Pixi vs Sesderma products

Questions and answers

Pixi or Sesderma: which is better?

Pixi offers a much wider range of products on this page and achieves a Superior Lovi fit for oily, acne-prone, and sensitive skin types, whereas Sesderma only features one product with moderate or lower fits for most skin types. Pixi products frequently utilize soothing ingredients like aloe vera, which helps with skin healing.

Iranian Journal of Medical Sciences, 2019

What is the difference between Pixi and Sesderma?

Pixi offers a wide variety of ten products on this page spanning toners, serums, and moisturizers, whereas Sesderma features only a single product, Azelac RU Serum. Furthermore, Pixi is rated with a Superior fit for oily, sensitive, and oily acne-prone skin types, while Sesderma has no skin types listed with a Superior fit.

Which is more affordable, Pixi or Sesderma?

This page does not provide pricing information to compare the affordability of Pixi and Sesderma.

Which causes fewer breakouts, Pixi or Sesderma?

Pixi offers a wide selection of products on this page with a Superior or High fit for acne-prone skin, such as Retinol Tonic and Glow Tonic, whereas Sesderma features only Azelac RU Serum, which has a High fit for acne-prone skin. Both brands contain key ingredients like aloe vera that help soothe the skin and reduce irritation.

Iranian Journal of Medical Sciences, 2019

Between Pixi and Sesderma, which brand was founded earlier and in which countries?

Sesderma was founded earlier in 1989 in Spain, while Pixi was founded in 1999 in the United Kingdom.

How do the fragrance inclusions compare across the products listed for Pixi and Sesderma?

Pixi offers a mix of options where 7 of the 10 products on this page list no fragrance, whereas the sole product listed for Sesderma includes fragrance. This means shoppers looking for fragrance-free choices have more variety within the Pixi range on this page.

Which products from Pixi achieve a Superior Lovi fit level for mature skin?

For mature skin, Glow Tonic and Retinol Tonic achieve a Superior Lovi fit level among the products on this page. Retinol helps stimulate collagen accumulation in naturally aged human skin.

The Journal of Investigative Dermatology, 2000

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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