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Pixi vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Pixi and Sesderma are distinguished skincare brands that bring targeted relief and gentle daily care to varying complexions. The British line, founded in 1999, is celebrated for its nourishing toners, targeted serums, soothing eye products, and hydrating moisturizers, suiting sensitive and dry sensitive skin best with gentle, balancing formulations like the Glow Tonic, Glow Peel Pads, and Retinol Tonic. Conversely, the Spanish enterprise, established in 1989, is beloved for advanced serums and meticulously engineered formulas featuring botanical extracts and active compounds that refine skin texture, catering ideally to sensitive, hyperpigmented, and aging skin through standout options such as the Azelac RU Serum. Ultimately, while both houses offer reliable solutions for acne-prone skin, they differ in their heritage and their specialized focus on either comforting daily routines or advanced dermatological engineering.

Pixi is a British skincare brand founded in 1999.

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Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Pixi and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Pixi vs Sesderma products

Questions and answers

Pixi or Sesderma: which is better?

Pixi offers a much wider range of products on this page with Superior or High Lovi fit levels across multiple skin types, whereas Sesderma is represented by only one product. Reviewers mostly mention deep hydration and radiance for Pixi, though some note a sticky residue and strong fragrance.

What is the difference between Pixi and Sesderma?

Pixi offers a wide variety of toners, mists, and serums with mostly gentle ingredients like aloe vera and hyaluronic acid, while Sesderma is represented on this page by just one serum, Azelac RU Serum. Lovi rates Pixi as a Superior fit for several skin types and concerns, whereas Sesderma achieves a High fit for acne-prone skin and dark spots.

Which is more affordable, Pixi or Sesderma?

The page facts do not provide pricing information to determine whether Pixi or Sesderma is more affordable.

Which causes fewer breakouts, Pixi or Sesderma?

Pixi offers several products on this page with a Superior fit for acne-prone skin, such as Glow Tonic and Retinol Tonic, while Sesderma features only the Azelac RU Serum, which has a High fit for acne-prone skin.

Which brand has been around longer and where were they founded, Pixi or Sesderma?

Sesderma has been around longer, having been founded in Spain in 1989, whereas Pixi was founded in the United Kingdom in 1999.

How many products from Pixi contain fragrance compared to Sesderma?

Seven of the ten Pixi products on this page list no fragrance, while the only Sesderma product on this page contains fragrance.

What are the key ingredients shared across Pixi products?

The products on this page from Pixi share aloe vera and hyaluronic acid as key ingredients. Hyaluronic acid helps improve skin hydration and wound healing.

Iranian Journal of Medical Sciences, 2019Journal of Pharmacy & Pharmaceutical Sciences, 2015

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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