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Pixi vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Pixi and Sesderma are distinguished skincare brands that offer thoughtfully formulated solutions for diverse complexions. The British line, founded in 1999, is loved for its nourishing toners, targeted serums, refreshing eye products, and hydrating moisturizers that suit dry skin and acne-prone skin best. Meanwhile, the Spanish brand, founded in 1989 and owned by Grupo Sesderma since 2026, is beloved for its advanced serums and meticulously engineered formulas tailored for sensitive, hyperpigmented, and aging skin types. While both utilize active compounds and botanical extracts to promote a radiant complexion, they differ in their specific product lineups and ideal skin matches.

Pixi is a British skincare brand founded in 1999.

pixibeauty.comtracxn.compitchbook.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Pixi and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Pixi vs Sesderma products

Questions and answers

Pixi or Sesderma: which is better?

Pixi offers a much wider range of products on this page, achieving a Superior Lovi fit for dry skin with items like Hydrating Milky Mist, while Sesderma is represented by only one product, Azelac RU Serum.

What is the difference between Pixi and Sesderma?

Pixi offers a much larger variety of products on this page across multiple categories like toners, serums, and moisturizers, whereas Sesderma is represented by only a single serum. Additionally, Pixi's products on this page achieve Superior fit levels for several skin types and include fragrance-free options, while Azelac RU Serum is the only Sesderma product listed and it contains fragrance.

Which is more affordable, Pixi or Sesderma?

This page does not contain pricing information, so a comparison of affordability between Pixi and Sesderma cannot be made.

Which causes fewer breakouts, Pixi or Sesderma?

For acne-prone skin, Lovi rates Pixi's Retinol Tonic as Superior and its Glow Tonic as Superior among the products on this page, while Sesderma's Azelac RU Serum is rated High. Aloe vera helps soothe skin, which may reduce irritation and breakouts.

Iranian Journal of Medical Sciences, 2019

Which brand has been around longer and in which country was each founded?

Sesderma has been around longer, having been founded in Spain in 1989, while Pixi was founded in the United Kingdom in 1999.

How do the fragrance ingredients compare between Pixi and Sesderma products listed on the page?

Pixi offers a mix on this page where 7 of 10 products list no fragrance, while the remaining items like Glow Tonic include it. In contrast, Azelac RU Serum is the only product listed for Sesderma on this page and it includes fragrance.

What skin types does Pixi fit best compared to Sesderma?

Pixi fits dry skin, acne-prone skin, and mature skin best, whereas the products on this page for Sesderma do not have a defined best-fit skin type. Lovi rates Pixi as having Superior fit levels for dry skin and acne-prone skin with items like Hydrating Milky Mist and Retinol Tonic, while Azelac RU Serum from Sesderma rates High for acne-prone skin and dark spots but Low for dry skin.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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