Anua Rice 7 + Ceramide for skin with dark spots

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Questions and answers

What the research says

• Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.

  The British Journal of Dermatology, 2002

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations.

  Heliyon, 2023

• A rice bran oil nanoemulsion formulated using low energy methods showed low irritation potential in vitro and improved skin moisture while maintaining normal skin pH in human volunteers during in vivo assessments.

  Journal of Nanobiotechnology, 2011

• Topical gel and cream formulations containing niosomes entrapped with rice bran bioactive compounds improved skin hydration, lightening, thickness, roughness, and elasticity in 30 human volunteers over 28 days compared to baseline.

  Pharmaceutical Biology, 2012

• Gel and cream formulations containing rice bran bioactive compounds entrapped in niosomes increased in vitro antioxidant activity (ORAC values of 20-28 micromol TE/g versus 16-18 micromol TE/g for placebo), enhanced lipid peroxidation inhibition in human sebum by about 1.5 times, and improved in vivo human skin hydration by approximately 3 to 30% depending on the measurement technique.

  Journal of Nanoscience and Nanotechnology, 2011

• Stirring Nukadoko fermented rice bran beds by hand leads to temporary settlement of microorganisms on human skin with quick shedding.

  FEMS Microbiology Letters, 2023

• Crude extracts from Sang 5 CMU rice bran and husk exhibited antioxidant, anti-inflammatory, anti-melanogenesis, and collagen-regulating properties by scavenging radicals, reducing TBARS and MMP-2 levels, inhibiting nitric oxide and melanin production, and upregulating antioxidant, collagen-associated, and downregulating pigmentary genes in cell models.

  Plants, 2024

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.

  Arzneimittel-Forschung, 2000

Ingredients

Rice Bran Water, Dipropylene Glycol, Glycerin, Methylpropanediol, Water, Butylene Glycol, Methyl Gluceth-10, Niacinamide, 1,2-Hexanediol, Panthenol, Hydroxyethyl Urea, Pentylene Glycol, Sodium Polyacrylate, Rice Extract, Caprylic Capric Triglyceride, Carbomer, Hydrogenated Lecithin, Ethylhexylglycerin, Polyquaternium-51, Adenosine, Allantoin, Sodium Phytate, Xanthan Gum, Ceramide Np, Hyaluronic Acid, Alpha-Arbutin, Angelica Keiskei Extract, Corchorus Olitorius Leaf Extract, Dioscorea Japonica Root Extract, Hibiscus Esculentus Fruit Extract, Nelumbo Nucifera Root Extract, Beta-Glucan, Tocopherol, Defatted Rice Bran Extract, Arbutin, Zinc Stearate, Defatted Rice Bran, Rice Bran, Hydrolyzed Rice Protein, Rice Seed Protein, Honey Extract, Hydrolyzed Hyaluronic Acid

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.