Allies of Skin Molecular Saviour Probiotics Treatment Mist for acne-prone skin

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Questions and answers

What the research says

• Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.

  International Journal of Medical Sciences, 2021

• Topical application of live Lactobacillus reuteri DSM 17938 and its lysate reduced proinflammatory IL-6 and IL-8 in UVB-R-induced inflammation models, with live bacteria also increasing aquaporin 3 expression and exhibiting antimicrobial activity against skin pathogens.

  Experimental Dermatology, 2019

• Combining 10% gluconolactone chemical peeling with oxybrasion or microneedle mesotherapy increased skin hydration and decreased sebum, pH, and TEWL in twenty-one Caucasian women, with no significant differences between the two methods.

  Skin Research and Technology, 2023

• Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients.

  The Australasian Journal of Dermatology, 1992

• Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris.

  The Journal of Clinical and Aesthetic Dermatology, 2020

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical spray powder containing hyaluronic acid and metallic silver reduced wound area, bacterial load, and improved overall clinical status and patient perception in 25 patients with chronic wounds over 28 days.

  Journal of Wound Care, 2019

• Chlorogenic acid-functionalized silver nanoparticles of Citrus sinensis in a gel matrix achieved a particle size of 71.78 nm and an entrapment efficiency of 79.42%, providing an effective drug carrier system for the topical treatment of acne.

  Journal of Cosmetic Dermatology, 2023

• Topical delivery of silver nanoparticles promotes rapid wound healing and improves cosmetic appearance in a dose-dependent manner in an animal model through antimicrobial properties, reduced inflammation, and modulation of fibrogenic cytokines.

  ChemMedChem, 2007

• Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls.

  Journal of the European Academy of Dermatology and Venereology, 2024

• Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2014

• Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity.

  The Journal of Clinical and Aesthetic Dermatology, 2025

• Mangifera indica extract-loaded green nanolipid carriers in topical emulsion amplified overall antioxidant effectiveness and antiaging activity compared to vehicle in human volunteers over three months.

  Biomedicines, 2022

• Mangifera indica extract reduced lipid production by 40% in sebocytes, improved sebum quality and quantity in Caucasian volunteers, reduced porphyrins expression, and decreased C. acnes lipase activity by 29% compared to placebo while protecting microbiota equilibrium.

  Molecules, 2022

• Mango butter-based foot care cream repaired worn and cracked skin in all human volunteers and exhibited a significant healing response in rat excision and incision wound models compared to untreated conditions.

  Indian Journal of Pharmaceutical Sciences, 2008

Ingredients

Water, Polysorbate 20, Niacinamide, Propanediol, Lactobacillus Ferment, Gluconolactone, Mangifera Indica Fruit Extract, Lactobacillus Lysate Ferment Filtrate, Yogurt, Zinc Pca, Bisabolol, Euterpe Oleracea Fruit Extract, Cucumis Sativus Fruit Extract, Aloe Barbadensis Leaf Juice Powder, Cocodimonium Hydroxypropyl Silk Amino Acids, Silver, Citrus Aurantium Dulcis Callus Culture Extract, Ergothioneine, Glutathione, Glycerin, Populus Tremuloides Bark Extract, Leuconostoc Radish Root Ferment Filtrate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Chrysin, N-Hydroxysuccinimide, Glutamylamidoethyl Imidazole, Xanthan Gum, Calcium Gluconate, Ethylhexylglycerin, Sorbic Acid, Sodium Benzoate, Sodium Gluconate, Steareth-20, Sodium Hydroxide, Phenoxyethanol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.