Kiehl's Ultra Light Daily UV Defense Aqua Gel SPF 50 for mature skin

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Questions and answers

What the research says

• Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects.

  International Journal of Cosmetic Science, 2018

• Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants.

  International Journal of Molecular Sciences, 2026

• Horse oil-spread and adenosine-loaded dissolving microneedle patches significantly improved skin elasticity, hydration, dermal density, and wrinkles compared with adenosine-loaded dissolving microneedle patches in 20 women without causing adverse events.

  Journal of Cosmetic Dermatology, 2019

• A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.

  Journal of Cosmetic Dermatology, 2020

• Microencapsulation of ethylhexyl triazone in lipid microparticles significantly reduced its in vivo human stratum corneum penetration by 45.7% compared to the nonencapsulated sunscreen.

  Skin Pharmacology and Physiology, 2019

• A topical sunscreen containing octyl triazone, phenylbenzimidazole sulfonic acid, and methylbenzylidene camphor prevented UVB-induced suppression of intercellular adhesion molecule-1 expression and mixed-lymphocyte reaction in epidermal cell cultures compared to control sunscreens with comparable SPF lacking octyl triazone.

  Toxicology in Vitro, 1994

• Oral and dermal administration of Uvinul A plus resulted in three major urinary metabolites accounting for 52% of the oral dose, with a very low estimated daily systemic exposure of 8.1-9.3 μg/d in volunteers not intentionally exposed.

  International Journal of Hygiene and Environmental Health, 2020

• Microfine titanium dioxide does not penetrate human skin when formulated in an oil-in-water emulsion with the pigment dispersed in the aqueous phase, compared to oily dispersions and liposomal encapsulation which allow deeper skin penetration.

  International Journal of Cosmetic Science, 2000

• Replacing microsized titanium dioxide and zinc oxide with nanoparticles in sunscreens eliminates opaqueness and alters UV protection balance while inducing (photo)cyto- and genotoxicity and penetrating viable skin layers during long-term exposures.

  Nanotechnology, Science and Applications, 2011

• Microfine zinc oxide and titanium dioxide do not penetrate the stratum corneum of porcine skin in vitro, indicating that their use in sunscreens does not pose a health risk from internal exposure.

  Toxicology in Vitro, 2006

• Gentiana lutea extract increases lipid synthesis and triglyceride levels in human primary keratinocytes in vitro via p38 MAPK and PPARgamma signaling, and significantly increases skin lipid content in a proof-of-concept trial of 33 volunteers compared to placebo.

  International Journal of Molecular Sciences, 2017

• Topical application of Gentiana lutea extract reduced average roughness, relief of the upper eyelid skin, and redness of dark circles in 22 subjects after 14 days compared to placebo.

  International Journal of Cosmetic Science, 2023

• Aqueous standardized leaf extracts of Moringa oleifera showed the highest human dermal fibroblast and human keratinocyte proliferation and migration properties, leading to the development of an alginate-pectin film dressing with optimal physicochemical properties.

  Journal of Ethnopharmacology, 2018

• Topical administration of Moringa oleifera seed extract on excision wounds in male albino rabbits significantly increased the wound healing rate, elevated TGF-β1, VEGF, and Type I collagen relative expression, and reduced inflammatory markers like IL-1β and TNF-α compared to untreated and MEBO-treated groups.

  Antioxidants, 2022

• Moringa oleifera leaf extracts provided significant UV protection with an SPF of 2 at 2% to 4% concentrations and showed no significant irritant potential in cosmetic formulations.

  Molecules, 2018

Ingredients

Water, Alcohol Denat, Diisopropyl Sebacate, Isopropyl Lauroyl Sarcosinate, Ethylhexyl Triazone, Propylene Glycol, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Titanium Dioxide, Glycerin, Methyl Methacrylate Crosspolymer, Drometrizole Trisiloxane, Tocopherol, Stearic Acid, Phenoxyethanol, Cetyl Alcohol, Palmitic Acid, Styrene Acrylates Copolymer, Ceteth-10, Caprylyl Glycol, Menthoxypropanediol, Dextrin Palmitate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Aluminum Hydroxide, Ammonium Polyacryloyldimethyl Taurate, Butylene Glycol, Potassium Hydroxide, Peg-8 Laurate, Disodium Edta, Adenosine, Myristic Acid, Gentiana Lutea Root Extract, Pentylene Glycol, Peppermint Extract, Butyrospermum Parkii Seedcake Extract, Shea Seedcake Extract, Rosa Gallica Flower Extract, Sorbitol, Moringa Oleifera Seed Extract, Disodium Phosphate, Citric Acid

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.