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RoC vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

RoC and Sesderma are a French skincare brand founded in 1957 and a Spanish skincare brand founded in 1989, respectively. RoC is fondly loved for its expertly formulated serums, eye products, moisturizers, cleansers, and more, all enriched with proven ingredients like glycerin and retinol, while the brand is beloved for its advanced serums and meticulously engineered formulas. The French brand suits mature skin and dry skin best, providing deeply nourishing care that addresses aging and dryness, whereas Sesderma suits sensitive, hyperpigmented, and aging skin types best. They differ in their origins, ownership timelines, and specific standout formulations, with both offering targeted solutions like the BARRIER RENEW GEL-TO-FOAM CLEANSER and the Azelac RU Serum for acne-prone skin.

RoC is a French skincare brand founded in 1957 and owned by Bridgepoint Group plc since 2024.

en.wikipedia.orgprnewswire.combeautymatter.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular RoC and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular RoC vs Sesderma products

RoC vs Sesderma serums and treatments

Questions and answers

RoC or Sesderma: which is better?

RoC offers a much wider range of products on this page that help with mature skin, dry skin, and dark spots, whereas Sesderma only features a single serum. Lovi rates RoC's products with High fit levels across several skin types.

What is the difference between RoC and Sesderma?

RoC offers a wide range of twelve products featuring ingredients like retinol and vitamin C that help reduce wrinkles, while Sesderma is represented by just one product on this page, the Azelac RU Serum. Lovi rates RoC as a High fit for mature skin, dry skin, and skin with dark spots, whereas the products on this page for Sesderma fit acne-prone skin and skin with dark spots at a High level.

The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007

Which is more affordable, RoC or Sesderma?

RoC reviewers sometimes note good value for the products on this page, whereas no pricing or affordability feedback is mentioned for Sesderma.

Which causes fewer breakouts, RoC or Sesderma?

For acne-prone skin, Lovi rates the products on this page from RoC as having a High to Average fit, while Sesderma's Azelac RU Serum also achieves a High fit.

How do the founding years and countries of origin compare between RoC and Sesderma?

RoC was founded in France in 1957, whereas Sesderma was founded in Spain in 1989. Both skincare brands have European origins, with RoC established over three decades earlier than Sesderma.

Which RoC products contain fragrance compared to the Azelac RU Serum by Sesderma?

Only two of the products on this page for RoC list fragrance, which are the Retinol Correxion Deep Wrinkle Serum and the Multi Correxion Revive + Glow Daily Serum. In comparison, the Azelac RU Serum by Sesderma also includes fragrance.

What key skincare ingredients are shared across the RoC product line?

The products on this page for RoC share key ingredients including glycerin, retinol, vitamin C, and hyaluronic acid. Retinol helps reduce signs of aging and stimulate collagen accumulation in naturally aged human skin.

The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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