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RoC vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

RoC and Sesderma are distinguished skincare brands that bring decades of European heritage to daily routines, with the French house founded in 1957 and the Spanish lab established in 1989. RoC is widely celebrated for its targeted serums, eye products, and moisturizers featuring glycerin and retinol, whereas the Spanish brand is beloved for its advanced serums and meticulously engineered formulas. The first brand suits mature skin and acne-prone skin best, while the latter caters thoughtfully to sensitive, hyperpigmented, and aging skin types. Ultimately, they differ through their distinct ingredient philosophies, as the French line relies on retinol and glycerin to increase collagen and skin hydration, while its counterpart utilizes botanical extracts and active compounds to refine texture and promote radiance.

RoC is a French skincare brand founded in 1957 and owned by Bridgepoint Group plc since 2024.

en.wikipedia.orgprnewswire.combeautymatter.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular RoC and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular RoC vs Sesderma products

RoC vs Sesderma serums and treatments

Questions and answers

RoC or Sesderma: which is better?

RoC stands out as the better choice on this page, offering a wide range of products tailored for mature, acne-prone, and dry skin, whereas Sesderma only features a single serum. RoC's retinol helps smooth fine lines and wrinkles while stimulating collagen accumulation in aged skin.

The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007

What is the difference between RoC and Sesderma?

RoC offers a wide range of products featuring key ingredients like retinol and vitamin C that fit mature, acne-prone, and dry skin best, whereas Sesderma features a single serum on this page that is rated High for acne-prone skin and skin with dark spots. Retinol helps reduce the signs of aging by stimulating collagen accumulation in naturally aged human skin.

The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007

Which is more affordable, RoC or Sesderma?

Reviewers note that RoC offers good value, whereas affordability details are not available for Sesderma on this page.

Which causes fewer breakouts, RoC or Sesderma?

When it comes to acne-prone skin, Lovi gives High ratings to several RoC products like the Barrier Renew Gel-to-Foam Cleanser and Sesderma's Azelac RU Serum. Both brands offer options that help with breakouts, but RoC has a wider range of products on this page rated High for acne-prone skin.

Which brand has been established longer, RoC or Sesderma?

RoC has been established longer, having been founded in France in 1957 compared to Sesderma, which was founded in Spain in 1989.

How many products from RoC contain fragrance compared to Sesderma?

On this page, 10 out of 12 RoC products list no fragrance while 2 contain it, whereas the single Sesderma product includes fragrance.

Which RoC product receives a Caution fit level for dry sensitive skin?

The RoC Retinol Correxion Deep Wrinkle Serum receives a Caution fit level for dry sensitive skin.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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