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RoC vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

RoC and Sesderma are distinguished skincare brands rooted in decades of dermatological heritage, with the French pioneer celebrated for expertly formulated serums, eye products, moisturizers, and cleansers enriched with glycerin and retinol, while the Spanish house is beloved for its advanced serums and meticulously engineered formulas. The former brand suits mature skin and skin with dark spots best, whereas the latter suits sensitive, hyperpigmented, and aging skin types best. Both brands differ largely in their ingredient philosophies and regional origins, offering targeted solutions such as glycerin to increase skin hydration and barrier function, and botanical extracts to refine skin texture and promote a radiant complexion.

RoC is a French skincare brand founded in 1957 and owned by Bridgepoint Group plc since 2024.

en.wikipedia.orgprnewswire.combeautymatter.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular RoC and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular RoC vs Sesderma products

RoC vs Sesderma serums and treatments

Questions and answers

RoC or Sesderma: which is better?

RoC is better for offering a wider variety of products on this page across multiple categories like cleansers, moisturizers, and sunscreens, while Sesderma features only a single serum. Reviewers note that RoC helps reduce wrinkles and fine lines, though some mention skin irritation and burning.

The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007

What is the difference between RoC and Sesderma?

RoC features a wide range of products including cleansers, sunscreens, and retinol treatments that help reduce wrinkles, while Sesderma currently presents a single serum focused on dark spots and acne-prone skin. Retinol helps stimulate collagen accumulation in naturally aged human skin.

The Journal of Investigative Dermatology, 2000

Which is more affordable, RoC or Sesderma?

When it comes to value, reviewers on this page sometimes note that RoC products offer good value, while the page has no pricing or value mentions for Sesderma.

Which causes fewer breakouts, RoC or Sesderma?

For acne-prone skin, the products on this page for RoC have a High fit with the BARRIER RENEW GEL-TO-FOAM CLEANSER and BARRIER RENEW AM MOISTURIZER SPF 30, whereas Sesderma's Azelac RU Serum also has a High fit.

Which brand was founded earlier, RoC or Sesderma, and in which countries were they established?

RoC was founded earlier than Sesderma, having been established in France in 1957 while Sesderma was founded in Spain in 1989.

How many products from RoC contain fragrance compared to Sesderma?

Ten out of twelve RoC products on this page list no fragrance while two contain it, whereas the single Sesderma product on this page includes fragrance.

What skin types does the Sesderma Azelac RU Serum have a High fit level for?

On this page, the Sesderma Azelac RU Serum has a High fit level for acne-prone skin, skin with dark spots, and combination skin.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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