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RoC vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

RoC and Sesderma are esteemed European skincare brands founded in France and Spain, respectively. The French line features nourishing glycerin and potent retinol within its serums, eye products, moisturizers, and cleansers to suit acne-prone and mature skin best. Meanwhile, the Spanish brand is beloved for advanced serums and meticulously engineered formulas that suit sensitive, hyperpigmented, and aging skin types. Both brands differ in their foundational compositions, offering targeted solutions such as the Barrier Renew Gel-To-Foam Cleanser and the Azelac RU Serum.

RoC is a French skincare brand founded in 1957 and owned by Bridgepoint Group plc since 2024.

en.wikipedia.orgprnewswire.combeautymatter.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular RoC and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular RoC vs Sesderma products

RoC vs Sesderma serums and treatments

Questions and answers

RoC or Sesderma: which is better?

RoC is better for most shoppers because the products on this page offer a much wider variety of options for different skin types and concerns, backed by key ingredients like retinol. Topical retinol helps stimulate collagen accumulation in naturally aged human skin.

The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007

What is the difference between RoC and Sesderma?

RoC offers a much larger variety of products across multiple categories with a High Lovi fit for mature and acne-prone skin, whereas Sesderma currently features only a single serum on this page. Retinol helps reduce the look of fine lines and wrinkles in aging skin.

The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007

Which is more affordable, RoC or Sesderma?

When it comes to affordability, reviewers sometimes note that RoC offers good value across the products on this page, whereas the page lists no pricing or value feedback for Sesderma.

Which causes fewer breakouts, RoC or Sesderma?

RoC has a High Lovi fit for acne-prone skin across the products on this page, whereas Sesderma is not highlighted for acne-prone routines here.

How does the country of origin and founding year compare between RoC and Sesderma?

RoC was founded in France in 1957, while Sesderma was founded in Spain in 1989.

Which brand offers more products with no fragrance, RoC or Sesderma?

RoC offers far more products with no fragrance, with 10 out of 12 products on this page listing no fragrance. In comparison, Sesderma has only one product on this page, and it includes fragrance.

What are the main key ingredients found across the products of RoC?

The products on this page from RoC include glycerin, retinol, vitamin C, and hyaluronic acid as their key ingredients. Retinol helps reduce signs of aging in skin.

The Journal of Investigative Dermatology, 2000Dermatologic Therapy, 2022

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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