Galderma vs Sesderma
Galderma and Sesderma are distinguished skincare houses originating from Switzerland and Spain, respectively. The Swiss brand specializes in targeted treatments like the Epiduo Gel and Benzac AC variants, which suit acne-prone and mature complexions, while the Spanish brand is beloved for advanced serums with botanical extracts that care for sensitive, hyperpigmented, and aging skin. Both offer carefully engineered formulas, yet they differ primarily in their heritage and specific active compounds designed to address distinct dermatological needs.
Galderma is a Swiss skincare brand founded in 1981 and owned by Galderma Group AG.
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Galderma and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Galderma vs Sesderma products
Galderma vs Sesderma serums and treatments
Questions and answers
Galderma or Sesderma: which is better?
Galderma is better for clearing acne, with products on this page earning a High Lovi fit for oily acne-prone skin. However, reviewers note that Galderma serums may cause severe dryness, peeling, and irritation. Azelac RU Serum by Sesderma achieves a High Lovi fit for skin with dark spots.
The Cochrane Database of Systematic Reviews, 2020Pharmaceutics, 2021
What is the difference between Galderma and Sesderma?
Galderma offers fragrance-free acne-clearing serums that achieve a High Lovi fit for oily and acne-prone skin, while Sesderma provides a serum with fragrance that achieves a High Lovi fit for dark spots and combination skin.
The Cochrane Database of Systematic Reviews, 2020Pharmaceutics, 2021
Which is more affordable, Galderma or Sesderma?
The products on this page for both Galderma and Sesderma do not list pricing information, so affordability cannot be compared.
Which causes fewer breakouts, Galderma or Sesderma?
Galderma has a High Lovi fit for acne-prone skin with the products on this page, whereas Sesderma also has a High Lovi fit for acne-prone skin with Azelac RU Serum. Both brands help clear acne, though Galderma may cause severe dryness, peeling, and irritation.
The Cochrane Database of Systematic Reviews, 2020Pharmaceutics, 2021
Between Galderma and Sesderma, which brand offers fragrance-free products?
Galderma offers fragrance-free options because every product on this page lists no fragrance in its ingredients. In contrast, the Azelac RU Serum by Sesderma includes fragrance.
How do the founding countries and years of Galderma and Sesderma compare?
Galderma was founded in Switzerland in 1981, whereas Sesderma was founded in Spain in 1989.
Which brand has products specifically suited for oily acne-prone skin with a High Lovi fit level?
Galderma has products on this page specifically suited for oily acne-prone skin with a High Lovi fit level, such as Epiduo Gel and Benzac AC 5. Sesderma's Azelac RU Serum holds an Average Lovi fit level for this skin type.
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.
