Galderma vs Sesderma
Galderma and Sesderma are distinguished skincare houses originating from Switzerland and Spain, respectively. The Swiss brand centers on targeted serums formulated for oily and acne-prone skin, with standout options like the Epiduo Gel and the Benzac AC series. Meanwhile, the Spanish brand is beloved for advanced serums and engineered formulas that suit sensitive, hyperpigmented, and aging skin types, highlighted by the Azelac RU Serum. Ultimately, both differ in their regional heritage, founding eras, and precise dermatological focus.
Galderma is a Swiss skincare brand founded in 1981 and owned by Galderma Group AG.
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Galderma and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Galderma vs Sesderma products
Galderma vs Sesderma serums and treatments
Questions and answers
Galderma or Sesderma: which is better?
Galderma is better for oily and acne-prone skin, as the products on this page have a High Lovi fit for those skin types, though reviewers note they may cause severe dryness and peeling. Sesderma is better for dark spots and combination skin, with Azelac RU Serum showing a High Lovi fit for those concerns.
The Cochrane Database of Systematic Reviews, 2020Pharmaceutics, 2021
What is the difference between Galderma and Sesderma?
Galderma best fits oily and acne-prone skin with fragrance-free serums like Epiduo Gel, whereas Sesderma offers Azelac RU Serum for dark spots and combination skin but includes fragrance. Reviewers note that Galderma effectively clears acne but may cause severe dryness and irritation.
The Cochrane Database of Systematic Reviews, 2020Pharmaceutics, 2021
Which is more affordable, Galderma or Sesderma?
The provided page facts do not contain pricing information, so it is not possible to determine whether Galderma or Sesderma is more affordable.
Which causes fewer breakouts, Galderma or Sesderma?
Galderma has a High fit for acne-prone skin with its acne-clearing serums, whereas Sesderma also has a High fit for acne-prone skin using Azelac RU Serum. Both brands help manage breakouts, but Galderma focuses specifically on oily, acne-prone skin types.
The Cochrane Database of Systematic Reviews, 2020Pharmaceutics, 2021
Where were Galderma and Sesderma founded and when?
Galderma was founded in Switzerland in 1981, and Sesderma was founded in Spain in 1989.
Which brand offers products that are completely fragrance-free according to their ingredient lists?
Galderma offers products on this page that all list no fragrance in their ingredients, unlike Sesderma.
How does the Lovi fit level for Azelac RU Serum compare between acne-prone skin and dry skin?
Lovi rates Azelac RU Serum as having a High fit for acne-prone skin and a Low fit for dry skin. The azelaic acid in the serum helps treat acne vulgaris.
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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