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Galderma vs Sesderma

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes 路 How the Fit score works

Galderma and Sesderma are distinguished skincare brands originating from Switzerland and Spain, respectively. The Swiss brand centers on targeted serums featuring active ingredients like benzoyl peroxide, fitting oily and combination skin best with standout options for acne-prone, hyperpigmented, and mature concerns. Meanwhile, the Spanish brand is beloved for its advanced serums and meticulously engineered formulas utilizing botanical extracts to suit sensitive, hyperpigmented, and aging skin types. Both brands differ primarily in their formulation philosophies, allowing users to select the ideal option for their specific dermatological needs.

Galderma is a Swiss skincare brand founded in 1981 and owned by Galderma Group AG.

en.wikipedia.org

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Galderma and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Galderma vs Sesderma products

Galderma vs Sesderma serums and treatments

Questions and answers

Galderma or Sesderma: which is better?

Galderma is better for oily and acne-prone skin, as the products on this page have a High Lovi fit level for those skin types, whereas Sesderma offers an Azelac RU Serum that has a High Lovi fit level for skin with dark spots. Reviewers mostly mention that Galderma provides effective acne-clearing serums, though severe dryness and peeling may occur.

The Cochrane Database of Systematic Reviews, 2020Pharmaceutics, 2021

What is the difference between Galderma and Sesderma?

Galderma best fits oily skin, combination skin, and oily acne-prone skin with fragrance-free serums, while the products on this page for Sesderma include fragrance and target dark spots. Galderma helps clear acne, but may cause severe dryness and irritation.

The Cochrane Database of Systematic Reviews, 2020Pharmaceutics, 2021

Which is more affordable, Galderma or Sesderma?

The provided page facts do not contain pricing information, so it is not possible to determine whether Galderma or Sesderma is more affordable based on this page.

Which causes fewer breakouts, Galderma or Sesderma?

Galderma is the better choice for acne-clearing serums, featuring products like Epiduo Gel and Benzac AC that have a High Lovi fit for acne-prone skin. Meanwhile, Sesderma offers Azelac RU Serum, which also has a High fit for acne-prone skin but includes fragrance. Reviewers note that Galderma's products help clear acne effectively, though they may cause severe dryness, peeling, and irritation.

The Cochrane Database of Systematic Reviews, 2020Pharmaceutics, 2021

Which brand has products formulated without fragrance, Galderma or Sesderma?

Galderma has products formulated without fragrance, as every product on this page from Galderma lists no fragrance in its ingredients. In contrast, Sesderma features a product on this page with fragrance.

How do the founding years and countries of origin compare between Galderma and Sesderma?

Galderma was founded in Switzerland in 1981, whereas Sesderma was founded in Spain in 1989.

What specific skin types are identified as the best fit for Galderma's brand-focused routines?

Galderma's brand-focused routines fit oily skin, combination skin, and oily acne-prone skin best.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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