Galderma vs Sesderma
Galderma and Sesderma are distinguished skincare houses originating from Switzerland and Spain, respectively. The Swiss brand centers on targeted serums like the Epiduo Gel and Benzac AC variants, serving oily, acne-prone, and mature skin best. Meanwhile, the Spanish brand is beloved for advanced serums and engineered formulas featuring botanical extracts, such as the Azelac RU Serum, which suit sensitive, hyperpigmented, and aging complexions. Ultimately, both offer specialized formulations, though their ideal skin types and core ingredient profiles differ.
Galderma is a Swiss skincare brand founded in 1981 and owned by Galderma Group AG.
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Galderma and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Galderma vs Sesderma products
Galderma vs Sesderma serums and treatments
Questions and answers
Galderma or Sesderma: which is better?
Galderma is better for oily and acne-prone skin, with Lovi fit levels rated High for serums like Epiduo and Benzac, while Sesderma is better for dark spots with its Azelac RU Serum. Benzoyl peroxide helps clear acne effectively.
What is the difference between Galderma and Sesderma?
Galderma features fragrance-free products on this page that are a High fit for oily and acne-prone skin, whereas Sesderma offers a serum that contains fragrance and achieves a High fit for acne-prone skin, combination skin, and skin with dark spots. Topical benzoyl peroxide helps treat acne, and azelaic acid helps manage acne vulgaris.
The Cochrane Database of Systematic Reviews, 2020Pharmaceutics, 2021
Which is more affordable, Galderma or Sesderma?
The products on this page do not list pricing information, so a comparison of affordability cannot be made between Galderma and Sesderma.
Which causes fewer breakouts, Galderma or Sesderma?
Galderma has a High Lovi fit for oily acne-prone skin with the products on this page, whereas Sesderma has an Average fit, making Galderma a better match for clearing breakouts. Benzoyl peroxide helps treat acne, though users note that severe dryness and irritation may occur.
The Cochrane Database of Systematic Reviews, 2020Pharmaceutics, 2021
Where were Galderma and Sesderma founded and in what years?
Galderma was founded in Switzerland in 1981, and Sesderma was founded in Spain in 1989.
Which brand on the page offers fragrance-free products, and which one contains fragrance?
Every product from Galderma on this page lists no fragrance in its ingredients, while Sesderma includes fragrance in its Azelac RU Serum.
How does the routine for dry skin differ when using Galderma products?
When following a Galderma-focused routine for dry skin, you use hydrating cleansers and toners alongside the brand's acne serums like Benzac AC 5, while Lovi rates these products as having a low fit for dry skin.
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.
