Clinique vs ISDIN
Clinique and ISDIN are established skincare brands offering thoughtful selections of moisturizers, serums, and eye products designed to support a balanced complexion. The American brand, founded in 1968, combines ingredients like hyaluronic acid, glycerin, and caffeine, suiting dry and oily skin best with formulations that balance moisture and control oil. Conversely, the Spanish brand, founded in 1975, unites elegant moisturizers, advanced sunscreens, and restorative serums to suit dry and sensitive skin best through gentle daily comfort and dependable protection. While both provide targeted solutions for acne-prone skin, dark spots, and mature skin, they differ in their regional roots, foundational ingredients, and primary skin-type affinities.
Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..
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ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
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This page compares some of the most popular Clinique and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Clinique vs ISDIN products
People Say
Hydration, plumping, and smoothing effects Mostly MentionedMostly Mentioned
- “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+”
- “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
Lightweight and fast-absorbing texture Often MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “sinks in immediately — Clinique moisture surge”
Gentle, non-irritating, and sensitive skin friendly Mostly MentionedOften Mentioned
- “never irritated my eyes — Clinique All About Eyes”
- “No stinging eyes — Clinique Take The Day Off Cleansing Balm”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Good makeup base and compatibility Often MentionedOften Mentioned
- “Melts waterproof mascara — Clinique Take The Day Off Cleansing Balm”
- “foundation glides on — Clinique moisture surge”
- “acts like a primer — ISDIN Eryfotona Actinica”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Morning glow and radiance Rarely NotedOften Mentioned
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
- “skin looks immediately luminous — ISDIN K-Ox Eyes”
- “softening fine lines — ISDIN Retinal Intense Serum”
- “wake up glowing — Clinique Moisture Surge Overnight Mask”
Controls oil and mattifies Sometimes NotedSometimes Noted
- “keeps me matte — Clinique Dramatically Different Moisturizing Gel”
- “absorbs quickly — Clinique Moisture Surge Overnight Mask”
- “dries down matte — ISDIN Eryfotona Actinica”
- “Non-greasy — ISDIN Hyaluronic Moisture”
High price point and cost concerns Often MentionedOften Mentioned
- “jar is too small for the cost — Clinique moisture surge”
- “quite pricey — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- “very expensive — ISDIN Eryfotona Actinica”
- “My only wish is that ISDIN would make this product in a bigger size bottle. — ISDIN Fusion Water”
Unpleasant scent or strong fragrance Sometimes NotedOften Mentioned
- “Smells like nail polish remover — Clinique Clarifying Lotion 2”
- “Smells like old oil — Clinique Take The Day Off Cleansing Balm”
- “Has a weird plastic-like smell — Clinique Dramatically Different Moisturizing Lotion+”
- “smell is overpowering — ISDIN Eryfotona Actinica”
Causes breakouts or skin irritation Often MentionedRarely Noted
- “mild redness or irritation — ISDIN K-Ox Eyes”
- “I think the serum is too strong for my face as it has burned and left very rough and a peeling face. — ISDIN Flavo-C Serum”
- “slight peeling — ISDIN Retinal Intense Serum”
- “Woke up with whiteheads on my chin — Clinique Dramatically Different Moisturizing Lotion+”
Clinique vs ISDIN routines for dry skin
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Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
S$25.06
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Hydrating Toner
COSRX Propolis Synergy Toner
Morning
S$41.07
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Moisturizer
Dramatically Different Moisturizing Lotion+
Morning · Evening · Once a week
S$37.33
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SPF
thinkbaby Safe Sunscreen SPF 50+
Morning
S$21.09
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
S$39.68
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Serum or Treatment
Peach & Lily Glass Skin Refining Serum
Evening · Once a week
S$63.44
-
Nourishing Mask
MEDIHEAL Collagen Essential Mask
Once a week
S$62.94
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Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
S$25.06
-
Hydrating Toner
COSRX Propolis Synergy Toner
Morning
S$41.07
-
Moisturizer
d'Alba First Spray Serum
Morning · Evening · Once a week
S$25.94
-
SPF
Eryfotona Actinica
Morning
S$110.01
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
S$39.68
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
S$161.49
-
Nourishing Mask
MEDIHEAL Collagen Essential Mask
Once a week
S$62.94
Buy Clinique routine · S$253.28 · 95% fit
Buy ISDIN routine · S$466.19 · 93% fitSee multi-brand routine · 99% fit
Clinique vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
S$30.40
-
Hydrating Toner
TROIAREUKE H+Cocktail Purifying Ampoule Toner
Morning · Once a week
S$168.51
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
S$13.55
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
S$28.72
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
S$70.21
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening · Once a week
S$36.48
-
Serum or Treatment
Peach & Lily Glass Skin Refining Serum
Evening · Once a week
S$63.44
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
S$89.14
-
Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
S$30.40
-
Hydrating Toner
TROIAREUKE H+Cocktail Purifying Ampoule Toner
Morning · Once a week
S$168.51
-
Moisturizer
SKIN1004 Centella Cream
Morning · Evening · Once a week
S$33.87
-
SPF
Eryfotona Actinica
Morning
S$110.01
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
S$70.21
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening · Once a week
S$36.48
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
S$161.49
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
S$89.14
Buy Clinique routine · S$486.90 · 94% fit
Buy ISDIN routine · S$700.11 · 91% fitSee multi-brand routine · 96% fit
Clinique vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
S$30.00
-
Hydrating Toner
Whamisa Organic Flowers Toner Deep Rich
Morning · Once a week
S$64.81
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
S$13.55
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
S$28.72
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
S$70.21
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening · Once a week
S$36.48
-
Serum or Treatment
Peach & Lily Glass Skin Refining Serum
Evening · Once a week
S$63.44
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
S$89.14
-
Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
S$30.00
-
Hydrating Toner
Whamisa Organic Flowers Toner Deep Rich
Morning · Once a week
S$64.81
-
SPF
Eryfotona Actinica
Morning
S$110.01
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
S$70.21
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening · Once a week
S$36.48
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
S$161.49
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
S$89.14
Buy Clinique routine · S$382.80 · 94% fit
Buy ISDIN routine · S$562.14 · 92% fitSee multi-brand routine · 97% fit
Questions and answers
Clinique or ISDIN: which is better?
Clinique and ISDIN are both great choices, as Lovi rates their routines as equal across all skin types. Clinique is often praised for its fragrance-free formulas, while ISDIN stands out for its lightweight texture and sunscreens.
What is the difference between Clinique and ISDIN?
Clinique is an American brand founded in 1968, whereas ISDIN is a Spanish brand founded in 1975. Clinique products on this page list no fragrance, while some ISDIN products contain fragrance.
Clinique or ISDIN for dry skin?
Both Clinique and ISDIN achieve a Superior routine fit level for dry skin. Reviewers note that the products on this page for both brands feature lightweight moisturizers, though ISDIN is sometimes noted for a strong fragrance while every product on this page for Clinique lists no fragrance.
Clinique or ISDIN: which moisturizer is better?
Both Clinique and ISDIN offer moisturizers with a high Lovi fit for dry skin, such as Clinique Smart Clinical Repair Lifting Face + Neck Cream and ISDIN Uradin Lotion 10. Reviewers often mention Clinique for hydrating and fast-absorbing formulas, while ISDIN is noted for lightweight textures.
Which is more affordable, Clinique or ISDIN?
Both Clinique and ISDIN have a high price point as a common drawback noted by reviewers, so neither brand is more affordable on this page.
Do Clinique and ISDIN products contain fragrance?
Every product on the Clinique page lists no fragrance in its ingredients. In contrast, 5 of the 8 ISDIN products on this page list fragrance.
Where and when were the parent companies of Clinique and ISDIN founded?
Clinique is owned by The Estée Lauder Companies Inc., which was founded in the United States in 1946, while ISDIN is owned by Puig, founded in Spain in 1914.
Which brand performs better for providing a morning glow and radiance?
ISDIN performs better for providing a morning glow and radiance compared to Clinique. The brand is noted for delivering a morning glow and radiance, making it a stronger choice for that specific effect.
Clinique or ISDIN for oily skin?
Both Clinique and ISDIN achieve a Superior Lovi fit level for oily skin. Reviewers note that ISDIN offers lighter textures and more radiance, while Clinique has no fragrance across the products on this page.
Clinique or ISDIN for sensitive skin?
Both Clinique and ISDIN achieve a Superior Lovi routine fit for sensitive skin. Reviewers find both brands gentle and friendly to sensitive skin, while every product on the Clinique page lists no fragrance.
Clinique or ISDIN for acne-prone skin?
Clinique and ISDIN are both well-suited for acne-prone skin, with Lovi fit levels reaching up to Superior for specific products across the products on this page. Clinique offers fragrance-free formulas, while ISDIN is noted for its ultralight sunscreens.
Research behind their key ingredients
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Algae extract protection effect on oxidized protein level in human stratum corneum
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Functional properties and skin care effects of sodium trehalose sulfate
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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