Clinique vs ISDIN
Clinique and ISDIN are established skincare lines, originating in America and Spain respectively, that offer thoughtful moisturizers, targeted serums, and soothing eye products. The American brand is widely loved for incorporating hydrating hyaluronic acid, nourishing glycerin, and invigorating caffeine to suit dry sensitive skin and oily skin best, while the Spanish brand is beloved for advanced sunscreens and expert formulas that suit sensitive skin and mature skin best. Both differ through their unique standout solutions, such as the former brand providing the Clarifying Do-Over Peel, for Men Oil-Free Moisturizer, and Smart Clinical Repair Lifting Face + Neck Cream, and the latter brand offering Fusion Water, Eryfotona Actinica, and K-Ox Eyes.
Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..
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ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
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This page compares some of the most popular Clinique and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Clinique vs ISDIN products
People Say
Hydration, plumping, and smoothing effects Mostly MentionedMostly Mentioned
- “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+”
- “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
Lightweight and fast-absorbing texture Often MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “sinks in immediately — Clinique moisture surge”
Gentle, non-irritating, and sensitive skin friendly Mostly MentionedOften Mentioned
- “never irritated my eyes — Clinique All About Eyes”
- “No stinging eyes — Clinique Take The Day Off Cleansing Balm”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Good makeup base and compatibility Often MentionedOften Mentioned
- “Melts waterproof mascara — Clinique Take The Day Off Cleansing Balm”
- “foundation glides on — Clinique moisture surge”
- “acts like a primer — ISDIN Eryfotona Actinica”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Morning glow and radiance Rarely NotedOften Mentioned
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
- “skin looks immediately luminous — ISDIN K-Ox Eyes”
- “softening fine lines — ISDIN Retinal Intense Serum”
- “wake up glowing — Clinique Moisture Surge Overnight Mask”
Controls oil and mattifies Sometimes NotedSometimes Noted
- “keeps me matte — Clinique Dramatically Different Moisturizing Gel”
- “absorbs quickly — Clinique Moisture Surge Overnight Mask”
- “dries down matte — ISDIN Eryfotona Actinica”
- “Non-greasy — ISDIN Hyaluronic Moisture”
High price point and cost concerns Often MentionedOften Mentioned
- “jar is too small for the cost — Clinique moisture surge”
- “quite pricey — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- “very expensive — ISDIN Eryfotona Actinica”
- “My only wish is that ISDIN would make this product in a bigger size bottle. — ISDIN Fusion Water”
Unpleasant scent or strong fragrance Sometimes NotedOften Mentioned
- “Smells like nail polish remover — Clinique Clarifying Lotion 2”
- “Smells like old oil — Clinique Take The Day Off Cleansing Balm”
- “Has a weird plastic-like smell — Clinique Dramatically Different Moisturizing Lotion+”
- “smell is overpowering — ISDIN Eryfotona Actinica”
Causes breakouts or skin irritation Often MentionedRarely Noted
- “mild redness or irritation — ISDIN K-Ox Eyes”
- “I think the serum is too strong for my face as it has burned and left very rough and a peeling face. — ISDIN Flavo-C Serum”
- “slight peeling — ISDIN Retinal Intense Serum”
- “Woke up with whiteheads on my chin — Clinique Dramatically Different Moisturizing Lotion+”
Clinique vs ISDIN routines for dry skin
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Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
€8.85
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Hydrating Toner
Paula's Choice Advanced Replenishing Toner
Morning
€34.00
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Moisturizer
d'Alba First Spray Serum
Morning · Evening · Once a week
€16.99
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SPF
Fusion Water
Morning
€25.99
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€10.97
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
-
Nourishing Mask
Abib Rice Probiotics Overnight Mask
Once a week
€15.30
-
Cleanser
all about clean
Morning · Evening · Once a week
€34.50
-
Hydrating Toner
Paula's Choice Advanced Replenishing Toner
Morning
€34.00
-
Moisturizer
Smart Clinical Repair Lifting Face + Neck Cream
Morning · Evening · Once a week
€48.89
-
SPF
Purito Daily Soft Touch Sunscreen
Morning
€12.98
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
€22.53
-
Serum or Treatment
Smart Clinical Repair Wrinkle Correcting Serum
Evening · Once a week
€71.30
-
Nourishing Mask
Moisture Surge Overnight Mask
Once a week
€24.50
Clinique vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
€20.50
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
SKIN1004 Centella Cream
Morning · Evening · Once a week
€17.49
-
SPF
Eryfotona Actinica
Morning
€32.49
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€97.52
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Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
€16.90
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€16.79
-
Cleanser
Redness Solutions Soothing Cleanser
Morning · Evening · Once a week
€25.50
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
€24.46
-
SPF
d'Alba UVessence Mild Waterfull Sun Cream SPF 50
Morning
€16.99
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
€22.53
-
Cleansing Toner
Clarifying Lotion 2
Evening
€34.39
-
Serum or Treatment
Smart Clinical Repair Wrinkle Correcting Serum
Evening · Once a week
€71.30
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€16.79
Clinique vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
€39.80
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
SPF
Eryfotona Actinica
Morning
€32.49
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€97.52
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€16.98
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
€28.50
-
Cleanser
all about clean
Morning · Evening · Once a week
€34.50
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
€24.46
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
€22.53
-
Cleansing Toner
Clarifying Lotion 2
Evening
€34.39
-
Serum or Treatment
Smart Clinical Repair Wrinkle Correcting Serum
Evening · Once a week
€71.30
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
€28.50
Questions and answers
Clinique or ISDIN: which is better?
ISDIN is the better option for skin routine fit because Lovi rates its overall routine fit as Superior across all skin types, whereas Clinique is rated High or Average depending on the skin type. Shoppers frequently mention ISDIN for its ultralight sunscreens and lightweight moisturizers, although some reviewers note a strong fragrance compared to Clinique which lists no fragrance on this page.
What is the difference between Clinique and ISDIN?
ISDIN offers a superior routine fit across all skin types compared to Clinique, and its sunscreens and lightweight textures are especially well-liked by shoppers. Meanwhile, every product on the Clinique page is free of added fragrance, making it less likely to cause scent-related irritation than ISDIN.
Clinique or ISDIN for dry skin?
ISDIN offers superior routine fit for dry skin compared to Clinique's average fit. Topical hyaluronic acid, a key ingredient found in the products on this page, helps improve skin quality and signs of skin aging.
Clinique or ISDIN: which moisturizer is better?
ISDIN is the better brand for moisturizers on this page, offering superior routine fits for dry skin and lightweight textures that shoppers love. Both brands feature hydrating ingredients like hyaluronic acid, but ISDIN provides better overall moisture performance.
Which is more affordable, Clinique or ISDIN?
Both Clinique and ISDIN share a high price point as a common drawback noted by reviewers, so neither brand stands out as more affordable.
Do Clinique products contain fragrance?
Every product on the Clinique page lists no fragrance in its ingredients, making the brand a suitable choice for shoppers who prefer scent-free skincare.
Which brand has better lightweight and fast-absorbing texture?
ISDIN does better than Clinique for a lightweight and fast-absorbing texture, thanks to its ultralight sunscreens and lightweight moisturizers.
How do the founding years and countries of origin compare between Clinique and ISDIN?
Clinique was founded in 1968 in the United States, whereas ISDIN was founded later in 1975 in Spain.
Clinique or ISDIN for oily skin?
ISDIN offers a Superior routine fit for oily skin compared to Clinique's High fit on this page, and reviewers frequently mention its ultralight sunscreens.
Clinique or ISDIN for sensitive skin?
ISDIN is a better fit for sensitive skin, earning a Superior routine fit rating compared to Clinique's High. Lovi shows that ISDIN offers particularly skin-friendly sunscreens, though reviewers note that some of its products carry a strong fragrance.
Clinique or ISDIN for acne-prone skin?
ISDIN is a better fit for acne-prone skin, as Lovi rates its routine as Superior compared to Clinique's Average fit. ISDIN also brings advantages in lightweight textures and morning radiance, though shoppers should keep in mind that its products sometimes carry a strong fragrance.
Research behind their key ingredients
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Algae extract protection effect on oxidized protein level in human stratum corneum
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Functional properties and skin care effects of sodium trehalose sulfate
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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