Clinique vs ISDIN
Clinique and ISDIN are established beauty companies founded in the twentieth century that offer thoughtfully crafted moisturizers, serums, eye products, and sunscreens. Both brands feature balanced formulas incorporating hydrating hyaluronic acid, nourishing glycerin, and invigorating caffeine to suit dry and sensitive skin. While the American brand also suits oily skin and relies on key ingredients to reduce wrinkles, restore barriers, and protect against UV radiation, the Spanish brand provides gentle daily comfort and dependable protection. Ultimately, these collections differ as one focuses on specialized solutions for diverse complexions, and the other delivers reliable daily support for a balanced complexion.
Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..
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ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
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This page compares some of the most popular Clinique and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Clinique vs ISDIN products
- moisture surge
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Take The Day Off Cleansing Balm
CA$55.00
-
Dramatically Different Moisturizing Lotion+
CA$61.00
-
All About Eyes
CA$82.00
-
Dramatically Different Moisturizing Gel
CA$61.00
-
Smart Clinical Repair Wrinkle Correcting Serum
CA$145.00
-
Moisture Surge Overnight Mask
CA$59.00
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Clarifying Lotion 2
CA$30.00
People Say
Hydration, plumping, and smoothing effects Mostly MentionedMostly Mentioned
- “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+”
- “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
Lightweight and fast-absorbing texture Often MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “sinks in immediately — Clinique moisture surge”
Gentle, non-irritating, and sensitive skin friendly Mostly MentionedOften Mentioned
- “never irritated my eyes — Clinique All About Eyes”
- “No stinging eyes — Clinique Take The Day Off Cleansing Balm”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Good makeup base and compatibility Often MentionedOften Mentioned
- “Melts waterproof mascara — Clinique Take The Day Off Cleansing Balm”
- “foundation glides on — Clinique moisture surge”
- “acts like a primer — ISDIN Eryfotona Actinica”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Morning glow and radiance Rarely NotedOften Mentioned
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
- “skin looks immediately luminous — ISDIN K-Ox Eyes”
- “softening fine lines — ISDIN Retinal Intense Serum”
- “wake up glowing — Clinique Moisture Surge Overnight Mask”
Controls oil and mattifies Sometimes NotedSometimes Noted
- “keeps me matte — Clinique Dramatically Different Moisturizing Gel”
- “absorbs quickly — Clinique Moisture Surge Overnight Mask”
- “dries down matte — ISDIN Eryfotona Actinica”
- “Non-greasy — ISDIN Hyaluronic Moisture”
High price point and cost concerns Often MentionedOften Mentioned
- “jar is too small for the cost — Clinique moisture surge”
- “quite pricey — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- “very expensive — ISDIN Eryfotona Actinica”
- “My only wish is that ISDIN would make this product in a bigger size bottle. — ISDIN Fusion Water”
Unpleasant scent or strong fragrance Sometimes NotedOften Mentioned
- “Smells like nail polish remover — Clinique Clarifying Lotion 2”
- “Smells like old oil — Clinique Take The Day Off Cleansing Balm”
- “Has a weird plastic-like smell — Clinique Dramatically Different Moisturizing Lotion+”
- “smell is overpowering — ISDIN Eryfotona Actinica”
Causes breakouts or skin irritation Often MentionedRarely Noted
- “mild redness or irritation — ISDIN K-Ox Eyes”
- “I think the serum is too strong for my face as it has burned and left very rough and a peeling face. — ISDIN Flavo-C Serum”
- “slight peeling — ISDIN Retinal Intense Serum”
- “Woke up with whiteheads on my chin — Clinique Dramatically Different Moisturizing Lotion+”
Clinique vs ISDIN routines for dry skin
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Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
CA$20.19
-
Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
CA$27.99
-
Moisturizer
Tata Harper Repairative Moisturizer
Morning · Evening · Once a week
CA$162.00
-
SPF
Fusion Water
Morning
CA$69.99
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
CA$17.99
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
CA$65.00
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
CA$29.99
-
Cleanser
all about clean
Morning · Evening · Once a week
CA$38.00
-
Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
CA$27.99
-
Moisturizer
Smart Clinical Repair Lifting Face + Neck Cream
Morning · Evening · Once a week
CA$107.00
-
SPF
d'Alba Piedmont Waterfull Mild Sunscreen
Morning
CA$38.00
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
CA$55.00
-
Serum or Treatment
Smart Clinical Repair Wrinkle Correcting Serum
Evening · Once a week
CA$145.00
-
Nourishing Mask
Moisture Surge Overnight Mask
Once a week
CA$59.00
Buy ISDIN routine · CA$393.15 · 94% fit
Buy Clinique routine · CA$469.99 · 74% fitSee multi-brand routine · 99% fit
Clinique vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
CA$20.96
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
CA$37.60
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
CA$29.98
-
SPF
Fusion Water
Morning
CA$69.99
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
CA$23.99
-
Cleansing Toner
Pixi Glow Tonic
Evening
CA$28.90
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
CA$65.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
CA$29.50
-
Cleansing Mask
Tatcha The Clarifying Clay Mask
Once a week
CA$95.00
-
Cleanser
Redness Solutions Soothing Cleanser
Morning · Evening · Once a week
CA$42.00
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
CA$37.60
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
CA$61.00
-
SPF
La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60
Morning
CA$35.95
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
CA$55.00
-
Cleansing Toner
Clarifying Lotion 2
Evening
CA$30.00
- Serum or Treatment Even Better Clinical Dark Spot Corrector Evening · Once a week
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
CA$29.50
-
Cleansing Mask
Tatcha The Clarifying Clay Mask
Once a week
CA$95.00
Buy ISDIN routine · CA$400.92 · 91% fit
Buy Clinique routine · CA$386.05 · 78% fitSee multi-brand routine · 96% fit
Clinique vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
CA$44.95
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
CA$37.60
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
CA$29.98
-
SPF
Fusion Water
Morning
CA$69.99
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
CA$23.99
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
CA$31.99
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
CA$65.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
CA$29.50
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
CA$50.00
-
Cleanser
all about clean
Morning · Evening · Once a week
CA$38.00
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
CA$37.60
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
CA$61.00
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
CA$20.96
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
CA$55.00
-
Cleansing Toner
Clarifying Lotion 2
Evening
CA$30.00
- Serum or Treatment Even Better Clinical Dark Spot Corrector Evening · Once a week
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
CA$29.50
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
CA$50.00
Buy ISDIN routine · CA$383.00 · 92% fit
Buy Clinique routine · CA$322.06 · 75% fitSee multi-brand routine · 96% fit
Questions and answers
Clinique or ISDIN: which is better?
ISDIN offers a Superior routine fit for dry, sensitive, oily, and acne-prone skin on the products on this page, while Clinique products on this page list no fragrance. Reviewers note that ISDIN provides a lightweight texture and morning glow, whereas Clinique is often mentioned for hydrating moisturizers.
What is the difference between Clinique and ISDIN?
ISDIN generally performs better across skin types, earning superior routine fit ratings compared to Clinique. Reviewers note that ISDIN excels with ultralight sunscreens and a morning glow, while Clinique products on this page list no fragrance.
Clinique or ISDIN for dry skin?
For dry skin, ISDIN offers a Superior Lovi routine fit while Clinique reaches an Average fit. ISDIN provides lightweight moisturizers and ultralight sunscreens, whereas the products on this page for Clinique are completely fragrance-free.
Clinique or ISDIN: which moisturizer is better?
ISDIN is the better choice for moisturizers on this page, as Lovi rates its routines as Superior across skin types while Clinique is rated High or Average. Reviewers also note that the products on this page for ISDIN provide a lighter and faster-absorbing texture.
Which is more affordable, Clinique or ISDIN?
Both Clinique and ISDIN have a high price point as a common drawback for the products on this page, so neither brand stands out as more affordable.
Between Clinique and ISDIN, which brand has products with no fragrance listed?
Clinique has products with no fragrance listed across the products on this page, whereas ISDIN lists fragrance in some of its products.
How do the founding years and countries of origin compare between Clinique and ISDIN?
Clinique was founded in the United States in 1968, while ISDIN was founded in Spain in 1975. Both brands are established names in skincare with origins in different countries.
Which brand performs better when it comes to morning glow and radiance?
ISDIN performs better when it comes to morning glow and radiance. Reviewers often mention its products provide a great morning glow, and the products on this page help improve radiance.
Clinique or ISDIN for oily skin?
ISDIN is superior for oily skin, whereas Clinique fits oily skin at a High level on this page. Reviewers note that ISDIN provides a lightweight and fast-absorbing texture along with a morning glow and radiance.
Clinique or ISDIN for sensitive skin?
For sensitive skin, both brands offer good choices, but Lovi rates ISDIN as Superior overall compared to High for Clinique. Clinique products on this page list no fragrance, whereas some ISDIN items feature strong fragrance.
Clinique or ISDIN for acne-prone skin?
ISDIN is superior for acne-prone skin, while Clinique has an average routine fit. ISDIN offers lightweight moisturizers and ultralight sunscreens that help maintain a clear complexion without heavy residue, though some reviewers note that certain products may cause breakouts.
Research behind their key ingredients
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Algae extract protection effect on oxidized protein level in human stratum corneum
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Functional properties and skin care effects of sodium trehalose sulfate
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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