SKIN1004 Madagascar Centella Probio-cica Intensive Ampoule for dry skin

High
- HighDry Skin Fit
- HighEffectiveness
- HighSafety
A great choice for dry skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your dry skin as Lactobacillus Centella Asiatica Extract Ferment Filtrate and Ceramide NP work synergistically to enhance skin barrier resilience and hydration, addressing dryness and flakiness.
- Betaine and Panthenol further support humectant action and soothing effects, complementing the primary barrier-repairing ingredients.
- The formulation is safe for your dry skin, containing no harsh ingredients and featuring soothing components like Centella Asiatica Extract and Panthenol.
How to apply
- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.8Overall rating based on 3.5k+ reviewsThis ampoule is widely celebrated for repairing damaged skin barriers and soothing irritation, particularly for dry, sensitive, or mature skin types. Users consistently praise its rich, milky texture that provides deep hydration and a radiant glow without a sticky residue. However, it is often deemed too heavy for oily skin or humid weather. This summary is based on a very large amount of data and should be definitely taken into account.
Highlights
Soothing and calming Mostly Mentioned
- “calms redness instantly”
- “comforting hug for angry barrier”
- “redness disappears overnight”
Deeply moisturizing Often Mentioned
- “skin has never felt so hydrated”
- “hydration fiesta”
- “plump and nourish the skin”
- “moisturizing enough to skip cream”
Luxurious texture Often Mentioned
- “milky but non-sticky”
- “absorbs like a dream”
- “smooth and silky finish”
- “leaves skin baby soft”
Barrier repair Sometimes Noted
- “heals moisture barrier faster”
- “restored my damaged barrier”
- “skin feels more resilient”
- “great for retinol users”
Too heavy Sometimes Noted
- “too oily for combo skin”
- “good winter serum, not summer”
- “felt a bit greasy”
- “sat on top of skin”
Caused breakouts Rarely Noted
- “broke me out slightly”
- “caused small whiteheads”
- “clogged my pores”
Dropper issues Rarely Noted
- “dropper takes while to fill”
- “hard to get product out”
- “prefer an airless pump”
- “pipette struggles with thick texture”
Scent concerns Rarely Noted
- “has an earthy scent”
- “subtle botanical aroma”
- “smell is a deal breaker”
- “fermented smell”
Sources: lovi.care, iherb.com, oliveyoung.com, stylevana.com, yesstyle.com, reddit.com, and more
Questions and answers
What makes SKIN1004 Probio-cica Intensive Ampoule a great fit for dry skin?
This treatment is a great fit for your dry skin because Lactobacillus Centella Asiatica Extract Ferment Filtrate and Ceramide NP work together to help repair the skin barrier and boost lasting hydration. Additional ingredients like Betaine and Panthenol bring extra soothing moisture to keep flaky skin feeling soft and smooth.
Which ingredients make this serum a good fit for dry skin?
Lactobacillus Centella Asiatica Extract Ferment Filtrate and Ceramide NP make this serum a great fit by strengthening the skin barrier and boosting hydration to tackle dryness and flakiness. Betaine and Panthenol help by drawing in moisture and keeping your skin calm.
What does Lactobacillus do for dry skin?
Lactobacillus helps keep dry skin calm and hydrated by supporting the skin barrier and reducing irritation and inflammation. Topical products and lysates containing these bacteria may improve moisture levels and protect against damage, though more support is often needed from richer ingredients like ceramides or hyaluronic acid to fully relieve very dry skin.
International Journal of Molecular Sciences, 2019Biochemical Society Transactions, 2021
What does Centella Asiatica Extract do for dry skin?
Centella asiatica extract helps dry skin by boosting moisture and reducing water loss while calming irritation. It supports barrier repair to keep the skin feeling soft and smooth.
Indian Journal of Pharmaceutical Sciences, 2016Clinical, Cosmetic and Investigational Dermatology, 2017
Where does this serum go in a skincare routine for dry skin?
This treatment goes in your evening routine after cleansing and before your moisturizer. Putting it in the evening keeps things simple and avoids extra safety concerns around sun exposure.
Can I use this serum with retinol, and in what order?
You can use this treatment alongside retinol by applying the treatment after your retinol or by alternating nights to keep your dry skin calm and comfortable. This pairing helps maintain hydration and supports your skin barrier while you use active ingredients.
How often should I use this serum?
This treatment is meant for your evening routine, used after cleansing and before moisturizing. You may use it every night since it is safe and gentle for dry skin, helping to keep it calm and hydrated.
Can this serum clog pores, cause breakouts or purging for dry skin?
Breakouts from this treatment are unlikely for dry skin since it contains no harsh ingredients and features soothing components. Some reviewers do mention it feels a bit heavy, so use a small amount if your skin easily feels overwhelmed by rich layers.
What the research says
A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin.
Skin Pharmacology and Physiology, 2022Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.
The Journal of Dermatological Treatment, 2017A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment.
Journal of Cosmetic Dermatology, 2025Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.
Journal of Alternative and Complementary Medicine, 2020A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.
Auris, Nasus, Larynx, 2020A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo.
Skinmed, 2021
Ingredients
Lactobacillus Centella Asiatica Extract Ferment Filtrate, Centella Asiatica Extract, Ceramide Np, Polyhydroxystearic Acid, Betaine, Allantoin, Panthenol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-

Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.
