Avène Cleanance Comedomed Anti-Blemish Concentrate for skin with dark spots
Avène Thermal Spring Water
Silybum Marianum Fruit Extract
Glycerin
Isopropyl Alcohol
SilicaLow
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
A weak match for skin with dark spots; the serums alongside fit it better.
This fit is calculated for the concerns frequently associated with dark spots: hyperpigmentation, sun spots, and uneven skin tone. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Suitable for normal skin due to the presence of silybum marianum fruit extract for its seboregulation and anti-inflammatory action, this product offers moderate treatment for acne-prone skin by helping to reduce blemishes.
- While it provides general skincare benefits like hydration and cleansing, it lacks specialized ingredients to effectively address your pigmentation concerns.
- The formulation is safe for your normal skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Apply this serum as part of your PM routine starting 3x/week and build up to daily use if your skin likes it.
- Place the serum after cleansing and toning, but before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute for it to absorb.
- Apply the serum on dry skin to help fade pigmentation effectively.
- Avoid the eye area and always use SPF 30+ during the day.
People Say
★4.3Overall rating based on 4.0k+ reviewsBased on a very large amount of data, this concentrate is highly effective for oily and acne-prone skin, significantly reducing active breakouts and preventing future blemishes. Users frequently praise its lightweight, fast-absorbing, and mattifying texture. A strong alcohol scent is commonly noted, and some users experience initial dryness or purging.
Highlights
Lightweight & fast-absorbing Mostly Mentioned
- “absorbs super fast”
- “watery gel texture”
- “non-greasy finish”
- “leaves skin matte”
Reduces blemishes Mostly Mentioned
- “significant reduction in blemishes”
- “keeps whiteheads at bay”
- “cleared my hormonal acne”
- “pores look smaller”
Strong alcohol scent Mostly Mentioned
- “powerful alcohol smell”
- “smells like hand sanitizer”
- “strong chemical odor”
- “scent is overpowering”
Controls oil Often Mentioned
- “mattifies the skin”
- “controls excess sebum”
- “less oily during the day”
- “shine-free complexion”
Prevents breakouts Sometimes Noted
- “limits recurrence of spots”
- “stops pimples forming”
- “prevented PMS breakouts”
- “keeps skin clear long-term”
Drying or peeling Sometimes Noted
- “made my face peel”
- “caused dry patches”
- “drying around the nose”
- “not moisturizing enough alone”
Initial skin purging Rarely Noted
- “sped up the purge”
- “broke out more at first”
- “worsened acne before improving”
- “caused small bumps initially”
Stinging sensation Rarely Noted
- “slight burning upon application”
- “stings sensitive areas”
- “tingling sensation”
- “irritated broken skin”
Sources: lovi.care, dermstore.com, aveneusa.com, beautycrew.com.au, hometesterclub.com, reddit.com, and more
Questions and answers
Why is Avène Cleanance Comedomed a weak match for skin with dark spots?
This product is a weak match because it lacks specialized ingredients to effectively address dark spots, even though it provides general hydration and blemish care. A treatment for dark spots needs a blend of effective antioxidants, soothing ingredients, and skin-repairing components like niacinamide and propolis to fade discoloration safely.
Which ingredients make this treatment a poor fit for skin with dark spots?
This treatment lacks specialized ingredients to effectively address your dark spots and pigmentation concerns. A product for this skin needs effective antioxidants, soothing ingredients, and skin-repairing components like niacinamide and propolis to fade dark spots and enhance skin radiance.
What does Avène Thermal Spring Water do for skin with dark spots?
Avène Thermal Spring Water is unlikely to directly treat or fade dark spots, as its main benefits are calming irritation and reducing redness on sensitive skin. A product for dark spots on this type of skin needs gentle brightening ingredients like vitamin C or niacinamide alongside soothing agents to improve skin tone without causing flare-ups.
What does Milk Thistle Fruit Extract do for skin with dark spots?
Milk thistle fruit extract helps fade dark spots and even out skin tone while soothing the skin. Studies show that topical creams containing this ingredient can lead to significant pigment improvement and lesion size reduction.
Where does this treatment go in a skincare routine for skin with dark spots?
This treatment goes in the evening routine before your moisturizer. Skin with dark spots needs targeted brightening ingredients like vitamin C, niacinamide, or acids to effectively fade discoloration.
Can I use this treatment with retinol, and in what order?
You can use this treatment in your evening routine alongside retinol by applying it before your moisturizer, but because it is a weak match for your skin with dark spots, a product of this type needs specialized brightening and pigment-fading ingredients to address dark spots effectively.
How often should I use this treatment?
You can use this treatment in the evening as part of your routine for skin with dark spots. Because this product lacks specialized ingredients to effectively fade dark spots, this skin needs targeted brighteners like vitamin C or niacinamide to help even out your skin tone.
Can this treatment clog pores, cause breakouts or purging for skin with dark spots?
This treatment is unlikely to clog pores, but reviewers note a low likelihood of initial skin purging. Because it is a weak match for skin with dark spots, a product of this type needs brightening ingredients like vitamin C or niacinamide to effectively fade dark spots.
Is this treatment fragrance-free and alcohol-free?
It has no fragrance and contains drying alcohol (isopropyl alcohol).
What the research says
Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes.
Life, 2023Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne.
The Medical Journal of Malaysia, 2024A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro.
International Journal of Cosmetic Science, 2025Silybum marianum flower extract increased human hair follicle dermal papilla cell proliferation and VEGF production while suppressing cellular senescence, and in a clinical study using hair shampoo, it significantly increased hair density and total hair count at 16 and 24 weeks compared with a placebo group.
Journal of Cosmetic Dermatology, 2024Topical 0.5% silymarin-loaded antioxidant serum applied twice daily significantly reduced clinical acne severity, lesion counts, and melanin pigmentation in 22 Korean acne patients over 4 weeks without associated adverse events.
Journal of Cosmetic Dermatology, 2023Topical silymarin cream 1.4% showed comparable results to salicylic acid 30% peels in reducing acne severity in 30 patients with mild to moderate acne vulgaris.
Journal of Cutaneous Medicine and Surgery, 2024A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001The use of 70% isopropyl alcohol in conjunction with scrubbing with a bristled brush significantly reduced positive bacterial cultures at the nail fold compared to povidone-iodine with soft sponges in volunteers.
The Journal of Bone and Joint Surgery. American Volume, 2005Friction with 70% ethyl or isopropyl alcohol immediately eliminates the heart-shaped pigmented lesion characteristic of terra firma-forme dermatosis in a 14-year-old boy.
Cureus, 2024Rubbing 70% isopropyl alcohol wipes cleared persistent reticulated brown patches in five patients with terra firma-forme dermatosis.
Skinmed, 2016A functional cosmetic cream containing bioactive materials from Streptomyces sp. T65 embedded in SBA-15 decreased skin roughness by 4.670% and increased skin brightness by 0.472% after 4 weeks of application, while demonstrating antimicrobial, antioxidant, anti-aging, and whitening activities.
Antioxidants, 2020Film-forming formulations containing porous silica achieved skin permeation rates comparable to immediate release formulations while confirming prolonged drug availability and causing no skin irritation in healthy volunteers.
European Journal of Pharmaceutical Sciences, 2017Topical treatment with silica mud and microalgae extracts from the Blue Lagoon improved skin barrier function by inducing epidermal gene expression and reducing transepidermal water loss in healthy humans, while preventing skin aging markers in vitro.
Experimental Dermatology, 2008
Why other serums fit skin with dark spots better
Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.
The British Journal of Dermatology, 2002Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening.
Dermatologic Therapy, 2022
Ingredients
Avène Thermal Spring Water Avène Aqua, Isopropyl Alcohol, Peg-6, Glycerin, Silybum Marianum Fruit Extract, Silica, Polyacrylate-13, Polyisobutene, Polysorbate 20, Sorbitan Isostearate, Water
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-
Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-
Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-
Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-
Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-
Medical Board
Cosmetic chemist, SCS, IFSCC member
-
Medical Board, Medical Advisor
Dermatology MD
-
Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-
Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.