Kiehl's Age Defender Eye Repair for mature skin

Questions and answers

What the research says

• Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects.

  International Journal of Cosmetic Science, 2018

• Horse oil-spread and adenosine-loaded dissolving microneedle patches significantly improved skin elasticity, hydration, dermal density, and wrinkles compared with adenosine-loaded dissolving microneedle patches in 20 women without causing adverse events.

  Journal of Cosmetic Dermatology, 2019

• Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants.

  International Journal of Molecular Sciences, 2026

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• A topical cosmetic slimming product containing tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol significantly reduced body circumferences and improved skin aspect compared with placebo in 78 women over 12 weeks.

  International Journal of Cosmetic Science, 2011

• Topical sunscreen formulations containing caffeine combined with UV filters increased in vivo anti-UVB protection by approximately 25% and showed higher SPF values compared to caffeine-free sunscreen, while being well tolerated by the skin of healthy subjects.

  Frontiers in Physiology, 2019

• Caffeine gel combined with choline geranate showed high skin permeation capacity and superior clinical results in cellulite treatment compared to caffeine gel without ionic liquid.

  AAPS PharmSciTech, 2021

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

• A flaxseed extract microemulgel produced statistically significant improvements compared to a placebo in skin erythema, melanin, sebum, moisture, and elasticity in 13 healthy human female volunteers.

  Pharmaceutics, 2022

• Hempseed or flaxseed oil-based lyotropic liquid crystals with the highest oil content and lecithin/Tween 80 mixture provided a 2-fold reduction in TEWL values and decreased skin erythema levels in healthy adult subjects compared to baseline.

  Acta Pharmaceutica, 2024

• Topical application of linseed, evening primrose, and olive oil emulsions accelerated wound closure in rats with excision wounds compared to untreated controls, though via different mechanisms.

  Drug Delivery and Translational Research, 2019

• Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

  Experimental Dermatology, 2003

• Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

  Journal of Periodontology, 2009

• Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

  Journal of Cosmetic Dermatology, 2022

Ingredients

Water, Glycerin, Dimethicone, Alcohol Denat, Theobroma Cacao Seed Butter, Butyrospermum Parkii Butter, Shea Butter, Poly C10-30 Alkyl Acrylate, Hydrogenated Polyisobutene, Sucrose Stearate, Stearic Acid, Palmitic Acid, Hydroxyethylpiperazine Ethane Sulfonic Acid, Synthetic Wax, Sodium Polyacrylate, Phenoxyethanol, Nylon-12, Pentylene Glycol, Caprylyl Glycol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Secale Cereale Seed Extract, Rye Seed Extract, Caffeine, Chlorphenesin, Xanthan Gum, Sodium Hydroxide, Ci 77891, Titanium Dioxide, Hydrolyzed Linseed Extract, Dimethiconol, Tocopherol, Mica, Myristic Acid, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Ascorbyl Glucoside, Adenosine, Glycine Soja Protein, Soybean Protein, Vaccinium Myrtillus Fruit Extract, Sodium Benzoate, Saccharum Officinarum Extract, Sodium Cocoyl Glutamate, Citrus Aurantium Dulcis Fruit Water, Fruit Water, Lemon Fruit Extract, Ethylhexylglycerin, Tin Oxide, Sugar Maple Extract, Potassium Sorbate, Citric Acid

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.