🇩🇪Germany

Paula's Choice Pro-Collagen Multi-Peptide Booster for dry sensitive skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Paula's Choice Pro-Collagen Multi-Peptide Booster

High

  • SuperiorDry Skin Fit
  • HighEffectiveness
  • HighSafety

A great choice for dry sensitive skin; a few serums fit it even better.

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Excellent suitability for your dry, sensitive skin as glycerin and sodium hyaluronate provide humectant action and polyglucuronic acid supports barrier repair, while multiple peptides like Palmitoyl Tripeptide-5 and Sh-Polypeptide-121 offer excellent skin firming and plumping benefits.
  • The formula also addresses your dry or flaky skin concerns by providing hydration and supporting skin barrier function.
  • The safety profile is excellent, with no risks of irritation due to the absence of prohibited or harsh ingredients.

How to apply

  • Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
  • Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
  • Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
  • Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
  • Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.

People Say

★4.5Overall rating based on 600+ reviews

Users report this lightweight gel booster provides immediate plumping and hydration, often improving skin texture and softening fine lines overnight. While it is highly effective for firming and layering, a moderate number of users found the scent and price to be drawbacks, and a low number experienced breakouts or redness.

Highlights

  • Plumps and firms Mostly Mentioned
    • “skin looks plumper”
    • “immediate firming benefit”
    • “complexion look bouncier”
    • “felt skin plumping up”
  • Hydrates and glows Often Mentioned
    • “instantly hydrates”
    • “gives a nice glow”
    • “leaves skin supple”
    • “soft and smooth”
  • Lightweight texture Often Mentioned
    • “melts into skin effortlessly”
    • “lightweight gel formula”
    • “layers seamlessly”
    • “absorbs instantly”
  • Expensive for size Often Mentioned
    • “price is astronomical”
    • “bottle size is smaller”
    • “bit pricey”
    • “doesn't last long”
  • Smooths lines Sometimes Noted
    • “wrinkle on forehead softened”
    • “makeup no longer creases”
    • “lines appear smoother”
    • “blur lines”
  • Messy packaging Sometimes Noted
    • “dropper can be unpredictable”
    • “release far more than desired”
    • “messy”
    • “hard to control”
  • Unpleasant scent Sometimes Noted
    • “smell like a mildewy rag”
    • “unpleasant mop-like odor”
    • “made me gag”
    • “scent is off-putting”
  • Caused breakouts Rarely Noted
    • “caused redness in cheek”
    • “break out very badly”
    • “closed comedones”
    • “not for sensitive skin”

Sources: lovi.care, paulaschoice.com, sephora.com, dermstore.com, skincarma.com, youtube.com, and more

Questions and answers

What makes Paula's Choice Multi-Peptide Booster a great fit for dry sensitive skin?

This booster is a great fit because glycerin and sodium hyaluronate draw in moisture while polyglucuronic acid helps repair the skin barrier, keeping dry and flaky patches comfortable and hydrated. At the same time, multiple peptides like Palmitoyl Tripeptide-5 firm and plump the skin safely without any harsh ingredients that could trigger sensitivity.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this booster a good fit for dry sensitive skin?

Glycerin and sodium hyaluronate make this booster a good fit by drawing in moisture, while polyglucuronic acid supports skin barrier repair. Additionally, multiple peptides like Palmitoyl Tripeptide-5 help firm and plump dry sensitive skin without causing irritation.

Clinical, Cosmetic and Investigational Dermatology, 2017Journal of Clinical Medicine, 2023

What does Peptide Complex do for dry sensitive skin?

Peptide Complex is a poor fit for dry sensitive skin because it lacks the deep moisture and barrier support needed by this skin type. A product for dry sensitive skin needs soothing ingredients like Centella asiatica and barrier-repairing ceramides to calm irritation and lock in hydration.

What does Hyaluronic Acid do for dry sensitive skin?

Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.

Journal of Drugs in Dermatology, 2011Dermatology and Therapy, 2021

Where does this booster go in a skincare routine for dry sensitive skin?

This booster goes in your evening routine after cleansing and toning, and before moisturizing. It is well suited for dry, sensitive skin because it provides deep hydration and supports the skin barrier without causing irritation.

Can I use this booster with retinol, and in what order?

You can use this booster with retinol by applying the booster first and following with your retinol to help keep your skin comfortable. The formula is unlikely to cause irritation and helps support your skin barrier while you use active ingredients.

Journal of Cosmetic Dermatology, 2024Clinical, Cosmetic and Investigational Dermatology, 2017

How often should I use this booster?

You can use this treatment in your evening routine, applying it after your toner and before your moisturizer. Some people may also use it in the morning or twice a day.

Can this booster clog pores, cause breakouts or purging for dry sensitive skin?

This booster is unlikely to cause breakouts for dry sensitive skin because it has a very low risk of clogged pores. Its safe, gentle formula helps keep skin calm without harsh ingredients.

Is this booster fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects.

    Colloids and Surfaces. B, Biointerfaces, 2025

  • Topical moisturizers improved skin barrier function and surface moisture, while a postbiotic moisturizer with yeast extract uniquely supported microbiome balance and modulated biomarkers of skin barrier, structure, and inflammation in participants and ex vivo explants exposed to environmental aggressors.

    Journal of Clinical Medicine, 2023

  • A cosmetic cream with 6% standardized wild apple fruit extract and a conventional emulsifier demonstrated stable antioxidant activity of 19.25 %RSC, increased skin moisturization, and a decreased melanin index by -31.40 without causing skin irritation.

    International Journal of Cosmetic Science, 2019

  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011

  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022

  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019

  • A maintenance therapy with a cosmeceutical formulation containing hydroxyphenoxy propionic acid, ellagic acid, yeast extract, and salicylic acid over 20 weeks significantly improved even skin tone, spot intensity, spot size, and overall hyperpigmentation in 33 healthy subjects with moderate facial dyspigmentation.

    Journal of Drugs in Dermatology, 2015

  • A methanol yeast extract increases proliferation and migration while decreasing entrance into senescence and apoptosis phases in 3T3 fibroblast cells.

    Journal of Cosmetic Science, 2014

  • Yeast extract from the A154 mutant strain increases cell viability by 1.4- to 1.9-fold in human skin cell lines (HFF, A431, HaCaT) after UVA irradiation and exhibits stronger ROS-scavenging properties compared with the parental strain.

    BMC Microbiology, 2026

  • Topical formulations containing 1.25% Malus sp. extract or 0.75% rutin protected against UVB-induced sunburn cells, caspase-3 activation, cyclobutane pyrimidine dimers, lipid peroxidation, and metalloproteinase formation in ex vivo skin explants and 3D tissue-engineered skin.

    Rejuvenation Research, 2020

Ingredients

Water, Glycerin, Pentylene Glycol, Hydrolyzed Yeast Extract, Pyrus Malus Fruit Extract, Dimethicone, Propanediol, 1,2-Hexanediol, Glyceryl Glucoside, Palmitoyl Tripeptide-72 Amide, Sh-Polypeptide-121, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-5, Tridecapeptide-1, Polyglucuronic Acid, Sodium Hyaluronate, C9-12 Alkane, Ammonium Polyacryloyldimethyl Taurate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Polygonum Bistorta Root Extract, Bacillus Ferment, Lecithin, Sodium Phytate, Coco-Caprylate Caprate, Hexylene Glycol, Cetyl Hydroxyethylcellulose, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Magnesium Chloride, Potassium Sorbate, Sodium Benzoate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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Prices checked 6 Nov 2026

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.

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