Paula's Choice 10% Azelaic Acid Booster for oily acne-prone skin
Azelaic Acid
Salicylic Acid
Licorice Root Extract
Glycerin
AdenosineHigh
- HighOily Skin Fit
- HighEffectiveness
- HighSafety
A great choice for oily acne-prone skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers high suitability for your oily skin, as azelaic acid and salicylic acid work to reduce redness, even skin tone, and provide moderate exfoliation to address your acne, blemishes, and breakouts. Licorice root extract and bisabolol further calm inflammation, complementing the seboregulating actions of these key ingredients.
- Adenosine and allantoin contribute to skin hydration and renewal, supporting the overall health of your oily skin.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components.
How to apply
- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
People Say
★4.5Overall rating based on 6.6k+ reviewsMost find the lightweight texture effective for smoothing bumps and clearing breakouts, though some users find the small tube size expensive and the natural scent off-putting.
Highlights
Fades dark spots Often Mentioned
- “acne scars faded”
- “hyperpigmentation is gone”
- “brightened dark spots”
- “marks disappearing quickly”
Reduces redness Often Mentioned
- “calmed redness immediately”
- “soothed my cheeks”
- “less flushed look”
Expensive for size Often Mentioned
- “tiny tube”
- “pricey for amount”
- “runs out fast”
- “wish it was bigger”
Clears acne Sometimes Noted
- “stopped hormonal breakouts”
- “shrunk cystic acne”
- “cleared stubborn pimples”
- “prevented new zits”
Lightweight consistency Sometimes Noted
- “absorbs instantly”
- “layers well”
- “non-greasy finish”
- “lightweight gel-cream”
Smooths texture Sometimes Noted
- “skin feels softer”
- “smoothed bumpy texture”
- “glass skin results”
- “reduced sebaceous filaments”
Unpleasant smell Sometimes Noted
- “smells like grain”
- “earthy scent”
- “weird funk”
- “overpowering smell”
Breakouts/Purging Rarely Noted
- “caused cystic acne”
- “bad purging”
- “broke me out”
- “worsened my skin”
Causes irritation Rarely Noted
- “stung my face”
- “caused dryness”
- “too strong”
- “damaged skin barrier”
Product pilling Rarely Noted
- “pills under makeup”
- “balls up”
- “rolls off skin”
- “doesn't layer well”
Sources: lovi.care, amazon.com, paulaschoice.co.uk, sephora.co.uk, dermstore.com, spacenk.com, and more
Questions and answers
What makes Paula's Choice Azelaic Acid Booster a great fit for oily acne-prone skin?
This treatment is a great fit because azelaic acid and salicylic acid reduce redness, even skin tone, and gently clear breakouts on oily skin. Licorice root extract and bisabolol help calm inflammation, while soothing ingredients keep the risk of irritation very low.
Which ingredients make this treatment a good fit for oily acne-prone skin?
Azelaic acid and salicylic acid make this treatment a great fit by helping to reduce redness, clear breakouts, and smooth your oily skin. Licorice root extract and bisabolol calm inflammation, while other soothing ingredients ensure an excellent safety profile without harsh irritation.
What does Azelaic Acid do for oily acne-prone skin?
Azelaic acid helps calm angry blemishes, clears out pores, and fades leftover dark marks on oily, acne-prone skin. It targets multiple root causes of breakouts by keeping bacteria in check and reducing swelling, which makes it very helpful for everyday management.
What does Salicylic Acid do for oily acne-prone skin?
Salicylic acid helps clear breakouts and keeps oily skin balanced by reducing oil levels and calming inflammation. It is well suited for oily, acne-prone skin because it targets pimples while helping keep the skin hydrated and protected.
Journal of Cosmetic Dermatology, 2025Experimental Dermatology, 2019
Where does this treatment go in a skincare routine for oily acne-prone skin?
This treatment goes in the evening routine after cleansing and before moisturizing. Putting treatments in the evening provides simplicity and extra safety around sun exposure for oily acne-prone skin.
Can I use this treatment with retinol, and in what order?
You can use this treatment with retinol by applying your retinol first and following with this treatment, or by using them on alternate nights to keep your skin calm. Because both ingredients help clear breakouts and smooth skin, using them together carefully helps you avoid dryness and irritation.
How often should I use this treatment?
Start using this treatment once a week in the evening, and if your skin handles it well, you can carefully use it more often. This gentle approach helps prevent irritation while managing blemishes and breakouts.
Can this treatment clog pores, cause breakouts or purging for oily acne-prone skin?
This treatment is unlikely to clog pores or cause breakouts on oily skin, as azelaic acid and salicylic acid work to reduce redness and provide moderate exfoliation while licorice root extract calms inflammation. It is very safe for this skin type with a low likelihood of irritation, thanks to the absence of harsh ingredients and the inclusion of soothing components.
Is this treatment fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.
What the research says
Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne.
Pharmaceutics, 2021Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability.
Journal of Cosmetic Dermatology, 2024Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo.
Dermatology and Therapy, 2024Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects.
International Journal of Cosmetic Science, 2018The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle.
Journal of Drugs in Dermatology, 2023Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks.
Journal of the European Academy of Dermatology and Venereology, 2023Topical administration of 20% azelaic acid cream and 5% tranexamic acid solution comparably improved acne-related postinflammatory hyperpigmentation in patients with acne vulgaris, while tranexamic acid demonstrated a significantly better safety profile at week 4.
Journal of Research in Medical Sciences, 2023Azelaic acid 15% gel showed comparable efficacy to adapalene 0.1% gel in reducing lesions, severity, and Dermatology Life Quality Index in women with adult acne, with significantly lower dryness and scaling, and demonstrated superiority during maintenance compared to no further treatment.
Journal of the European Academy of Dermatology and Venereology, 2015Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients.
CMAJ, 2010A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase.
BioMed Research International, 2020Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy.
Journal of Cosmetic Dermatology, 2024Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism.
Evidence-based Complementary and Alternative Medicine, 2015Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo.
Experimental Dermatology, 2015Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide.
Advanced Science, 2025A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months.
The Journal of Dermatology, 2008Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants.
International Journal of Molecular Sciences, 2026Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts.
International Journal of Molecular Sciences, 2021
Ingredients
Water, Azelaic Acid, C12-15 Alkyl Benzoate, Caprylic Capric Triglyceride, Methyl Glucose Sesquistearate, Glycerin, Cetearyl Alcohol, Glyceryl Stearate, Dimethicone, Salicylic Acid, Adenosine, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Boerhavia Diffusa Root Extract, Allantoin, Bisabolol, Cyclopentasiloxane, Xanthan Gum, Sclerotium Gum, Propanediol, Butylene Glycol, Phenoxyethanol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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