🇺🇸United States

Good Molecules vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Good Molecules and Sesderma are skincare brands offering thoughtful serums, moisturizers, eye products, exfoliants, and advanced formulas. The American brand, founded in 2019, features glycerin and hyaluronic acid to suit dry and dry sensitive skin best, while the Spanish brand, founded in 1989, suits sensitive, hyperpigmented, and aging skin types best. Both brands provide standout options for targeted concerns, such as the Overnight Exfoliating Treatment, Sheer Mineral Sunscreen SPF 30, and Yerba Mate Wake Up Eye Gel from the first, and the Azelac RU Serum from the second. They differ primarily in their founding heritage and proprietary active ingredients, with the former utilizing moisture-binding formulas and the latter employing botanical extracts and active compounds.

Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..

beautymatter.comgoodmolecules.compitchbook.compreqin.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Good Molecules and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Good Molecules vs Sesderma products

Good Molecules vs Sesderma serums and treatments

Questions and answers

Good Molecules or Sesderma: which is better?

Good Molecules is the better choice on this page because it offers a wide variety of fragrance-free products that Lovi rates high for dry, sensitive, and oily skin types, whereas Sesderma features only a single serum containing fragrance.

What is the difference between Good Molecules and Sesderma?

Good Molecules offers a wide range of products that are entirely free of fragrance, whereas Sesderma features a serum that includes fragrance. Additionally, Good Molecules fits dry skin, dry sensitive skin, and oily skin best, while Sesderma does not list specific skin types that it fits best.

Which is more affordable, Good Molecules or Sesderma?

Good Molecules offers affordable and great value serums, whereas pricing details for Sesderma are not highlighted on this page.

Which causes fewer breakouts, Good Molecules or Sesderma?

Good Molecules offers multiple products on this page rated High for acne-prone skin, such as the Hyaluronic Acid Serum and Overnight Exfoliating Treatment, while reviewers sometimes note breakouts as a risk. Sesderma features only one product on this page, Azelac RU Serum, which is rated High for acne-prone skin.

When and where were Good Molecules and Sesderma founded?

Good Molecules was founded in 2019 in the United States, while Sesderma was founded in 1989 in Spain.

How many products are listed for Sesderma compared to Good Molecules on the page?

Sesderma has only one product listed on the page, while Good Molecules features nineteen products.

Which brand offers products containing fragrance, Good Molecules or Sesderma?

Sesderma offers products containing fragrance, as its Azelac RU Serum lists fragrance, whereas all the products on the Good Molecules page list no fragrance in their ingredients.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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