Estée Lauder DayWear Moisturizer for mature skin

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Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• A triple combination of ergothioneine, collagen peptides, and sodium hyaluronate attenuated UV-induced skin damage ex vivo and improved facial skin hydration, elasticity, barrier function, and wrinkles in Chinese women.

  Frontiers in Nutrition, 2026

• Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo.

  Skin Research and Technology, 2024

• Topical sunscreen formulations containing caffeine combined with UV filters increased in vivo anti-UVB protection by approximately 25% and showed higher SPF values compared to caffeine-free sunscreen, while being well tolerated by the skin of healthy subjects.

  Frontiers in Physiology, 2019

• Encapsulation of ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane in lipid microparticles significantly reduced their in vivo human skin penetration compared to nonencapsulated filters.

  Skin Pharmacology and Physiology, 2011

• Microencapsulation of the BMDBM/HP-beta-CD complex in lipid microparticles significantly decreased the percutaneous penetration of the UV filter into the stratum corneum of human volunteers compared to the non-encapsulated sunscreen agent.

  Journal of Pharmaceutical and Biomedical Analysis, 2011

• Following human skin application of an O/W emulsion containing 2% BMDBM loaded in lipospheres, 15% of the sunscreen accumulated in the uppermost layers of the stratum corneum without remarkably modifying skin permeation compared to unencapsulated sunscreen.

  Skin Pharmacology and Physiology, 2008

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

  Experimental Dermatology, 2003

• Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

  Journal of Periodontology, 2009

• Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

  Journal of Cosmetic Dermatology, 2022

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

  Journal of Drugs in Dermatology, 2012

• A topical cosmetic slimming product containing tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol significantly reduced body circumferences and improved skin aspect compared with placebo in 78 women over 12 weeks.

  International Journal of Cosmetic Science, 2011

• Caffeine gel combined with choline geranate showed high skin permeation capacity and superior clinical results in cellulite treatment compared to caffeine gel without ionic liquid.

  AAPS PharmSciTech, 2021

• Caffeine stimulates metabolic activity in hair follicles and acts as an antioxidant through adenosine pathway interactions, showing potential as an effective and safe management option for hair loss despite current study limitations.

  Molecules, 2025

Ingredients

Avobenzone, Octisalate, Water, Dimethicone, Butyloctyl Salicylate, Butylene Glycol, Polyester-8, Cetyl Ricinoleate, Steareth-21, Steareth-2, Di-C12-15 Alkyl Fumarate, Caprylic Capric Myristic Stearic Triglyceride, Polysilicone-11, Psidium Guajava Fruit Extract, Gentiana Lutea Root Extract, Polygonum Cuspidatum Root Extract, Stearyl Alcohol, Hordeum Vulgare Extract Extrait Dorge Extract, Laminaria Ochroleuca Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Wheat Extract Germ Extract, Artemia Extract, Caffeine, Pentylene Glycol, Hydrolyzed Rice Extract, Vitis Vinifera Seed Extract Grape Seed Extract, Hydrolyzed Rice Bran Extract, Lauryl Peg-9 Polydimethylsiloxyethyl Dimethicone, Thermus Thermophillus Ferment, Behenyl Alcohol, Acrylic Acid Vp Crosspolymer, Triacontanyl Pvp, Glycerin, C12-15 Alkyl Benzoate, Linoleic Acid, Cholesterol, Squalane, Sodium Pca, 2-Hexanediol, Urea, Caprylic Capric Triglyceride, Dipropylene Glycol Dibenzoate, Tocopheryl Acetate, Acrylamide Sodium Acryloyldimethyltaurate Copolymer, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Ergothioneine, Isohexadecane, Ppg-15 Stearyl Ether Benzoate, Glycyrrhetinic Acid, Trehalose, Polyquaternium-51, Polysorbate 80, Potassium Sorbate, Lecithin, Hydrogenated Lecithin, Glucose, Palmitoyl Hydroxypropyltrimonium Amylopectin Glycerin Crosspolymer, Caprylyl Glycol, Cyclodextrin, Sodium Hydroxide, Nordihydroguaiaretic Acid, Sodium Chloride, Triacetin, Ascorbyl Tocopheryl Maleate, Parfum, Citric Acid, Ethylbisiminomethylguaiacol Manganese Chloride, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Disodium Edta, Bht, Chlorphenesin, Sodium Dehydroacetate, Phenoxyethanol, Blue 1 Ci 42090, Yellow 5 Ci 19140, Chromium Hydroxide Green Ci 77289

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.