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Lancôme vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Lancôme and Sesderma are a French brand founded in 1935 and a Spanish brand founded in 1989, respectively. The French brand is beloved for its sophisticated moisturizers, eye products, serums, and toners formulated with glycerin, hyaluronic acid, and adenosine, while the Spanish brand is beloved for its advanced serums and meticulously engineered formulas. Both suit sensitive skin best, though the former also suits acne-prone skin and the latter suits hyperpigmented and aging skin. They differ in their origins, specific active compositions, and tailored offerings such as the Tonique Confort and Azelac RU Serum.

Lancôme is a French skincare brand founded in 1935 and owned by L'Oréal S.A. since 1964.

loreal.comen.wikipedia.orgcosmeticsbusiness.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Lancôme and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Lancôme vs Sesderma products

Questions and answers

Lancôme or Sesderma: which is better?

Lancôme offers a wide selection of 14 products on this page featuring ingredients like glycerin and hyaluronic acid, whereas Sesderma only features the Azelac RU Serum. Lovi rates Lancôme as a High fit for sensitive skin, acne-prone skin, and dry skin.

Dermatologic Therapy, 2022

What is the difference between Lancôme and Sesderma?

Lancôme offers a wide selection of 14 skincare products on this page suited best for sensitive, acne-prone, and dry skin, whereas Sesderma features only the Azelac RU Serum. Both brands include fragrance in their formulations on this page, but Lancôme provides diverse options containing glycerin and hyaluronic acid.

Dermatologic Therapy, 2022

Which is more affordable, Lancôme or Sesderma?

Reviewers note that Lancôme has a high price point, whereas affordability details are not available for Sesderma on this page.

Which causes fewer breakouts, Lancôme or Sesderma?

When it comes to acne-prone skin, Lancôme has an High Lovi fit for several of the products on this page, whereas Sesderma is represented by Azelac RU Serum which also holds a High Lovi fit for acne-prone skin. Both brands feature products that help target breakouts effectively.

When was each brand founded and which country are they from?

LancBme was founded in France in 1935, while Sesderma was founded in Spain in 1989.

How many products are listed for Lancome versus Sesderma on this page?

Lancôme has 14 products listed on this page, while Sesderma has 1 product listed.

Which Lancome products are specifically recommended for dry skin or mature skin?

For dry skin, the products on this page such as Tonique Confort and Absolue Precious Oil achieve a High Lovi fit level, while Advanced Génifique Youth Activating Concentrate and Advanced Génifique Night Cream reach High for mature skin. Topical hyaluronic acid helps maintain skin hydration and improve signs of aging.

Dermatologic Therapy, 2022

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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