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Lancôme vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Lancôme and Sesderma are a French brand founded in 1935 and a Spanish brand founded in 1989, respectively. The French brand is beloved for its sophisticated moisturizers, eye products, serums, and toners formulated with glycerin, hyaluronic acid, and adenosine, suiting dry, mature, acne-prone, and uneven skin best. Meanwhile, the Spanish brand is beloved for advanced serums and meticulously engineered formulas with botanical extracts and active compounds that suit sensitive, hyperpigmented, and aging skin types. Both differ in their specific ingredient profiles, yet each brand offers targeted solutions like the Tonique Confort, Advanced Génifique products, and the Azelac RU Serum to refine the complexion.

Lancôme is a French skincare brand founded in 1935 and owned by L'Oréal S.A. since 1964.

loreal.comen.wikipedia.orgcosmeticsbusiness.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Lancôme and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Lancôme vs Sesderma products

Questions and answers

Lancôme or Sesderma: which is better?

Both brands offer solid options, but Lancôme has a much larger selection on this page with high Lovi fit levels for dry and sensitive skin. Reviewers note that Lancôme provides deep hydration and soothes sensitive skin, though it comes with a high price point.

Dermatologic Therapy, 2022

What is the difference between Lancôme and Sesderma?

Lancôme offers a much wider selection of skincare items on this page, whereas Sesderma is represented by a single serum. Reviewers note that Lancôme products often provide deep hydration and help soothe sensitive skin, but they also tend to have a high price point.

Which is more affordable, Lancôme or Sesderma?

Shoppers on this page note that Lancôme has a high price point, while information on Sesderma's pricing is not provided here.

Which causes fewer breakouts, Lancôme or Sesderma?

When it comes to acne-prone skin, Lancôme has products on this page like Advanced Génifique Youth Activating Concentrate that achieve a High fit level, whereas Sesderma offers Azelac RU Serum which also reaches a High fit level for acne-prone skin. Both brands thus feature options that are well-suited for skin prone to breakouts.

When was each brand founded and where?

Lancôme was founded in 1935 in France, while Sesderma was founded in 1989 in Spain.

Which brand has more products listed on the page?

Lancôme has more products listed on the page, with fourteen items compared to Sesderma's single product.

Do any products from either brand contain no fragrance?

Yes, 3 of the 14 products on this page from Lancôme list no fragrance, while Sesderma's sole product on this page contains fragrance.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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