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Lancôme vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Lancôme and Sesderma are a French brand founded in 1935 and a Spanish brand founded in 1989, respectively. The French brand is beloved for its sophisticated moisturizers, eye products, serums, and toners formulated with glycerin, hyaluronic acid, and adenosine, while the Spanish brand is beloved for its advanced serums and meticulously engineered formulas. Both suit sensitive skin best, though the former also suits acne-prone skin and the latter suits hyperpigmented and aging skin. They differ in their origins, specific active compositions, and tailored offerings such as the Tonique Confort and Azelac RU Serum.

Lancôme is a French skincare brand founded in 1935 and owned by L'Oréal S.A. since 1964.

loreal.comen.wikipedia.orgcosmeticsbusiness.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Lancôme and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Lancôme vs Sesderma products

Questions and answers

Lancôme or Sesderma: which is better?

Lancôme offers a wider variety of products on this page with High fits for sensitive, acne-prone, and mature skin, whereas Sesderma features only one product.

What is the difference between Lancôme and Sesderma?

Lancôme offers fourteen products on this page spanning cleansers, toners, serums, and moisturizers with a High Lovi fit for sensitive and acne-prone skin, while Sesderma features only the Azelac RU Serum with a High Lovi fit for acne-prone skin and skin with dark spots. Topical hyaluronic acid, present across Lancôme products, helps provide skin benefits.

Dermatologic Therapy, 2022

Which is more affordable, Lancôme or Sesderma?

Reviewers note that Lancome has a high price point, while pricing for Sesderma is not mentioned on this page.

Which causes fewer breakouts, Lancôme or Sesderma?

Both Lancôme and Sesderma offer products on this page with an Average or High Lovi fit level for acne-prone skin, meaning both are unlikely to cause breakouts when chosen correctly for your skin type.

When were Lancôme and Sesderma founded and in which countries?

Lancôme was founded in 1935 in France, while Sesderma was founded in 1989 in Spain.

Which brand has more products listed on the page, Lancôme or Sesderma?

Lancôme has more products listed on the page, offering fourteen items compared to Sesderma's single product.

How does the Lovi fit level of Azelac RU Serum compare for acne-prone skin versus dry skin?

Azelac RU Serum has a High Lovi fit level for acne-prone skin, while its fit level for dry skin is Low.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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