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Shu Uemura vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Shu Uemura and Sesderma are distinguished skincare brands, hailing from Japan and Spain respectively, that offer meticulously crafted formulas for diverse complexions. The former is celebrated for its transformative makeup removers, including a cleansing oil ideal for acne-prone skin, while the latter is beloved for advanced serums like the Azelac RU Serum that address similar concerns. Shu Uemura suits all skin types best through gentle and effective offerings, whereas Sesderma is tailored primarily for sensitive, hyperpigmented, and aging skin. Ultimately, both houses differ in their geographical origins, founding years, and targeted botanical or active compounds.

Shu Uemura is a Japanese skincare brand founded in 1967 and owned by L'Oréal S.A. since 2003.

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Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Shu Uemura and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Shu Uemura vs Sesderma products

Questions and answers

Shu Uemura or Sesderma: which is better?

For acne-prone skin or dark spots, Sesderma is better because the products on this page achieve a High Lovi fit level, whereas Shu Uemura only reaches Low or Caution. However, Sesderma's Azelac RU Serum contains fragrance, while Shu Uemura lists no fragrance in its cleansing oil.

What is the difference between Shu Uemura and Sesderma?

Shu Uemura offers cleansing oil, which gets an Average Lovi fit for dry and sensitive skin, whereas Sesderma features Azelac RU Serum, which achieves a High Lovi fit for acne-prone skin and skin with dark spots. The products on this page by Shu Uemura list no fragrance, while Sesderma includes fragrance in its serum.

Which is more affordable, Shu Uemura or Sesderma?

Neither Shu Uemura nor Sesderma has pricing information on this page, so affordability cannot be compared here.

Which causes fewer breakouts, Shu Uemura or Sesderma?

For acne-prone skin, the products on this page by Sesderma achieve a High fit, whereas Shu Uemura cleansing oil earns a Low fit and requires caution. Azelaic acid helps treat acne vulgaris.

Pharmaceutics, 2021

How do the founding years and countries of origin compare between Shu Uemura and Sesderma?

Shu Uemura was founded in Japan in 1967, whereas Sesderma was founded in Spain in 1989.

Which brand offers a cleansing oil, and which brand offers the Azelac RU Serum?

Shu Uemura offers the cleansing oil, while Sesderma offers the Azelac RU Serum. Every product on the Shu Uemura page lists no fragrance, whereas the Azelac RU Serum by Sesderma includes fragrance.

How does the presence of fragrance differ between the products of Shu Uemura and Sesderma?

Every product on this page by Shu Uemura lists no fragrance in its ingredients. In contrast, none of the products on this page by Sesderma list no fragrance, as the Azelac RU Serum contains fragrance.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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