Paula's Choice Pro-Collagen Multi-Peptide Booster for oily skin
6x Peptide Complex
Sodium Hyaluronate
Hydrolyzed Yeast Extract
Pyrus Malus Fruit Extract
Palmitoyl Tripeptide-5
Average
- SuperiorOily Skin Fit
- AverageEffectiveness
- ExcellentSafety
Works for oily skin; other serums fit it better.
- Clinical, Cosmetic and Investigational Dermatology, 2017
- Colloids and Surfaces. B, Biointerfaces, 2025
This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for your oily skin as Glycerin and Sodium Hyaluronate provide essential hydration without heavy emollients, while multiple peptides like Palmitoyl Tripeptide-5 and Sh-Polypeptide-121 support skin firming and plumping.
- While beneficial for general skin health and hydration, the formula lacks specialized ingredients to directly address concerns like oily shine.
- The product is safe for your oily skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
People Say
★4.5Overall rating based on 600+ reviewsUsers report this lightweight gel booster provides immediate plumping and hydration, often improving skin texture and softening fine lines overnight. While it is highly effective for firming and layering, a moderate number of users found the scent and price to be drawbacks, and a low number experienced breakouts or redness.
Highlights
Plumps and firms Mostly Mentioned
- “skin looks plumper”
- “immediate firming benefit”
- “complexion look bouncier”
- “felt skin plumping up”
Hydrates and glows Often Mentioned
- “instantly hydrates”
- “gives a nice glow”
- “leaves skin supple”
- “soft and smooth”
Lightweight texture Often Mentioned
- “melts into skin effortlessly”
- “lightweight gel formula”
- “layers seamlessly”
- “absorbs instantly”
Expensive for size Often Mentioned
- “price is astronomical”
- “bottle size is smaller”
- “bit pricey”
- “doesn't last long”
Smooths lines Sometimes Noted
- “wrinkle on forehead softened”
- “makeup no longer creases”
- “lines appear smoother”
- “blur lines”
Messy packaging Sometimes Noted
- “dropper can be unpredictable”
- “release far more than desired”
- “messy”
- “hard to control”
Unpleasant scent Sometimes Noted
- “smell like a mildewy rag”
- “unpleasant mop-like odor”
- “made me gag”
- “scent is off-putting”
Caused breakouts Rarely Noted
- “caused redness in cheek”
- “break out very badly”
- “closed comedones”
- “not for sensitive skin”
Sources: lovi.care, paulaschoice.com, sephora.com, dermstore.com, skincarma.com, youtube.com, and more
Questions and answers
How well does Paula's Choice Pro-Collagen Multi-Peptide Booster work for oily skin?
Paula's Choice Pro-Collagen Multi-Peptide Booster works moderately well for oily skin, as Sodium Hyaluronate and Glycerin provide essential hydration without heavy oils, while peptides support firming. However, it lacks specialized ingredients to directly manage oily shine, which treatments for this skin type need alongside sebum-controlling components like niacinamide.
Clinical, Cosmetic and Investigational Dermatology, 2017Colloids and Surfaces. B, Biointerfaces, 2025
Which ingredients make this serum a good fit for oily skin?
Glycerin and Sodium Hyaluronate make this serum a good fit for oily skin by providing essential hydration without heavy emollients. To work best for oily skin of this type, a treatment needs sebum-controlling ingredients like niacinamide and zinc PCA to manage shine and pores.
Clinical, Cosmetic and Investigational Dermatology, 2017Dermatologic Therapy, 2022
What does Peptide Complex do for oily skin?
Peptide complex helps smooth fine lines and keeps oily skin looking firm while improving overall texture. It may also help boost hydration without making your skin feel heavy or greasy.
What does Hyaluronic Acid do for oily skin?
Hyaluronic acid helps oily skin by reducing extra oil and sebum production without causing irritation. Clinical studies show it successfully balances oil levels while keeping the skin comfortable.
Where does it go in a skincare routine for oily skin?
This treatment goes in the evening routine after cleansing and before moisturizing, as putting treatments in the evening provides simplicity and extra safety around sun exposure. Oily skin also needs specialized ingredients like niacinamide or clay to directly address concerns like oily shine.
Can I use this serum with retinol, and in what order?
Yes, you can use this serum with retinol by applying it before your retinol treatment. It provides hydration and firming peptides without heavy oils, though oily skin also needs specialized ingredients to control shine.
Clinical, Cosmetic and Investigational Dermatology, 2017Colloids and Surfaces. B, Biointerfaces, 2025
How often should I use it?
You can use this treatment in your evening routine for simplicity and extra safety around sun exposure. It is safe for your oily skin and provides light hydration with helpful peptides, though this type of skin needs extra ingredients that directly control oily shine.
Clinical, Cosmetic and Investigational Dermatology, 2017Colloids and Surfaces. B, Biointerfaces, 2025
Can this serum clog pores, cause breakouts or purging for oily skin?
This serum is unlikely to cause breakouts or clog pores on oily skin because it has a safe profile with soothing components and no harsh ingredients. However, because it is an average fit, oily skin needs a product of this type that also includes specialized ingredients to control oily shine.
Is it fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects.
Colloids and Surfaces. B, Biointerfaces, 2025Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.
Dermatologic Therapy, 2022A cosmetic cream with 6% standardized wild apple fruit extract and a conventional emulsifier demonstrated stable antioxidant activity of 19.25 %RSC, increased skin moisturization, and a decreased melanin index by -31.40 without causing skin irritation.
International Journal of Cosmetic Science, 2019Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical moisturizers improved skin barrier function and surface moisture, while a postbiotic moisturizer with yeast extract uniquely supported microbiome balance and modulated biomarkers of skin barrier, structure, and inflammation in participants and ex vivo explants exposed to environmental aggressors.
Journal of Clinical Medicine, 2023A maintenance therapy with a cosmeceutical formulation containing hydroxyphenoxy propionic acid, ellagic acid, yeast extract, and salicylic acid over 20 weeks significantly improved even skin tone, spot intensity, spot size, and overall hyperpigmentation in 33 healthy subjects with moderate facial dyspigmentation.
Journal of Drugs in Dermatology, 2015A methanol yeast extract increases proliferation and migration while decreasing entrance into senescence and apoptosis phases in 3T3 fibroblast cells.
Journal of Cosmetic Science, 2014Topical formulations containing 1.25% Malus sp. extract or 0.75% rutin protected against UVB-induced sunburn cells, caspase-3 activation, cyclobutane pyrimidine dimers, lipid peroxidation, and metalloproteinase formation in ex vivo skin explants and 3D tissue-engineered skin.
Rejuvenation Research, 2020
Why other serums fit oily skin better
A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.
Journal of Cosmetic Dermatology, 2024Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022
Ingredients
Water, Glycerin, Pentylene Glycol, Hydrolyzed Yeast Extract, Pyrus Malus Fruit Extract, Dimethicone, Propanediol, 1,2-Hexanediol, Glyceryl Glucoside, Palmitoyl Tripeptide-72 Amide, Sh-Polypeptide-121, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-5, Tridecapeptide-1, Polyglucuronic Acid, Sodium Hyaluronate, C9-12 Alkane, Ammonium Polyacryloyldimethyl Taurate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Polygonum Bistorta Root Extract, Bacillus Ferment, Lecithin, Sodium Phytate, Coco-Caprylate Caprate, Hexylene Glycol, Cetyl Hydroxyethylcellulose, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Magnesium Chloride, Potassium Sorbate, Sodium Benzoate
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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