Estée Lauder Futurist Peptide-Power Serum Primer for oily acne-prone skin

Acetyl Hexapeptide-8
Palmitoyl Hexapeptide-12
Sodium Hyaluronate
Glycerin
Tetrahexyldecyl Ascorbate
Average
- HighOily Skin Fit
- AverageEffectiveness
- HighSafety
Works for oily acne-prone skin; other moisturizers fit it better.
- Clinical, Cosmetic and Investigational Dermatology, 2017
- American Journal of Clinical Dermatology, 2013
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate benefits for your oily skin, as Glycerin and Sodium Hyaluronate provide excellent hydration and plumping effects, which are supportive for acne and breakouts. Acetyl Hexapeptide-8 and Palmitoyl Hexapeptide-12 also contribute to extracellular matrix synthesis, further enhancing skin's appearance.
- Whey Lactis Proteine Du Petit-Lait Protein and Tetrahexyldecyl Ascorbate offer additional soothing and antioxidant benefits, complementing the primary hydrating ingredients for overall skin health.
- The product is safe for your skin, with no reported irritation risks due to the absence of harsh ingredients and the inclusion of beneficial components.
How to apply
- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
People Say
★4.1Overall rating based on 200+ reviewsThis serum-gel primer is highly praised for its hydrating, plumping, and smoothing effects, making it an excellent choice for mature skin or those seeking a radiant, dewy finish. While it excels at creating a smooth, makeup-ready canvas, some users find the packaging frustrating and the price point high for the amount of product provided.
Highlights
Intense hydration Often Mentioned
- “Skin feels more hydrated than it does with the Advanced Night Repair serum.”
- “Maintains its hydration... even in dry conditions.”
- “Provides intense and lasting hydration.”
Radiant finish Often Mentioned
- “Imparts a subtle, healthy sheen that isn't overly oily.”
- “Gives off... just the right amount to make your complexion look fresh and healthy.”
- “Luminous finish.”
Makeup-gripping base Sometimes Noted
- “Creates a beautiful makeup-gripping base.”
- “Preps it perfectly for makeup.”
- “Helps makeup stay in place for longer.”
Smooths fine lines Sometimes Noted
- “Fine lines around my eyes and forehead looked a bit softer.”
- “Reduces the look of fine lines and wrinkles in just 4 weeks.”
- “Smooths the look of fine lines and wrinkles.”
High price/value Sometimes Noted
- “The price is a little steep.”
- “Bottle is just not a good value, it is barely filled.”
- “There are other options that deliver similar results without the luxury price tag.”
Poor packaging Sometimes Noted
- “The dropper is glass... it had cracked from use.”
- “Packaging is also disappointing and feels less refined.”
- “I don't know why it's not in a squeeze tube.”
Heavy/comedogenic concerns Rarely Noted
- “This primer feels quite heavy.”
- “May contain ingredients that could be comedogenic for some skin types.”
Sources: lovi.care, johnlewis.com, macys.com, esteelauder.com, youtube.com, saveozo.com, and more
Questions and answers
How well does Estée Lauder Futurist Peptide-Power work for oily acne-prone skin?
This serum works moderately well for your oily acne-prone skin, as glycerin and sodium hyaluronate help provide good hydration and plumping that support breakouts while posing little risk of irritation. A product of this type needs lightweight hydration, oil regulation, and soothing ingredients without heavy oils or pore-clogging components to truly excel on this skin.
Which ingredients make this serum a good fit for oily acne-prone skin?
Glycerin and Sodium Hyaluronate make this serum a good fit for oily acne-prone skin because they provide essential hydration without adding heavy oils or clogging pores. Oily acne-prone skin needs lightweight hydrators, anti-inflammatory ingredients, and oil-regulating components like Niacinamide to stay balanced and clear.
What does Argireline do for oily acne-prone skin?
Argireline is unlikely to treat acne or oiliness directly, as it focuses on reducing fine lines and making skin smooth. Oily acne-prone skin needs lightweight, non-greasy ingredients that clear pores and calm breakouts.
American Journal of Clinical Dermatology, 2013Journal of Cosmetic and Laser Therapy, 2013
What does Palmitoyl Hexapeptide-12 do for oily acne-prone skin?
Palmitoyl Hexapeptide-12 helps strengthen and repair the skin barrier, which is useful when dealing with oily, acne-prone skin that has been dried out by treatments. It sinks into the outer skin layers to support overall health and resilience, though oily skin of this type also needs lightweight, non-greasy ingredients that balance moisture without clogging pores.
Where does this serum go in a skincare routine for oily acne-prone skin?
This treatment goes in the evening routine after cleansing and before your moisturizer. Oily acne-prone skin needs a product of this type to include lightweight hydrating ingredients like glycerin and sodium hyaluronate along with soothing components to help balance oil and calm breakouts.
Can I use this serum with retinol, and in what order?
Yes, you can use this serum with retinol by applying the serum first to hydrate your skin and then following with retinol. This type of routine needs barrier-strengthening ingredients like ceramides and soothing components to keep oily acne-prone skin balanced and protected.
How often should I use this serum?
You can use this serum in the evening as part of your routine, though some similar products may also be used in the morning or twice a day. Daily application helps improve skin moisture and overall appearance while keeping irritation unlikely.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?
This serum is unlikely to clog pores or cause breakouts for oily acne-prone skin, as it has a very low chance of feeling heavy and contains no harsh ingredients. To be a better fit for this skin, a product of this type needs oil-absorbing minerals or lightweight salicylic acid to help control excess shine.
Can I use this serum around the eyes or on my body?
You can use this moisturizing treatment around your eyes and on your body, as it has a safe profile with no reported irritation risks. However, for the thin skin around the eyes and larger areas of the body, this skin type needs targeted lightweight hydration and soothing ingredients without heavy oils to prevent clogged pores.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.
American Journal of Clinical Dermatology, 2013A 3-in-1 anti-aging topical night serum-in-oil applied once daily decreased wrinkles by 11%, increased skin firmness by 8%, reduced redness by 70%, and improved overall skin quality and complexion in 103 female subjects over 28 to 84 days compared to baseline.
Journal of Cosmetic Dermatology, 2019Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days.
Annals of Dermatology, 2019Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear.
Journal of Cosmetic Dermatology, 2017Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy.
European Journal of Neurology, 2013A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.
Journal of Cosmetic Dermatology, 2015Palmitoyl hexapeptide-12 permeates the stratum corneum and epidermis, initiating gel formation via endogenous ions and strengthening and repairing the skin barrier after delipidation in human skin.
ACS Applied Bio Materials, 2025Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022
Ingredients
Water, Butylene Glycol, Glycerin, Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Sodium Pca, Whey Lactis Proteine Du Petit-Lait Protein, Glycine Soja Protein Soybean Protein, Sodium Hyaluronate, Acetyl Glucosamine, Lactobacillus Ferment, Tetrahexyldecyl Ascorbate, Chlorella Vulgaris Extract, Algae Extract, Caprylyl Glycol, Caffeine, Hydrolyzed Rice Extract, Laminaria Digitata Extract, Glucose, Artemia Extract, Sucrose, Peg-8, Xanthan Gum, Sodium Polyacryloyldimethyl Taurate, Calcium Chloride, Glyceryl Polymethacrylate, Sodium Hydroxide, Propanediol, Bht, Tocopheryl Acetate, Disodium Edta, Silica, Phenoxyethanol, Potassium Sorbate, Chlorphenesin, Mica, Titanium Dioxide Ci 77891, Iron Oxides Ci 77492, Bismuth Oxychloride, Carmine
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Dr. Sofía Perea Pérez, MD, MSc
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Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Specialist dermatologist, MBBS, MD, IFAAD
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Dermatology MD
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Elina Nazarenko, MD
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Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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