SKIN1004 Madagascar Centella Probio-cica Intensive Ampoule for dry sensitive skin
Lactobacillus Centella Asiatica Extract Ferment Filtrate
Ceramide Np
Allantoin
PanthenolHigh
- HighDry Skin Fit
- HighEffectiveness
- HighSafety
One of the best serums for dry sensitive skin.
This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Excellent for your dry and sensitive skin as Lactobacillus Centella Asiatica Extract Ferment Filtrate and Ceramide NP provide significant hydration and barrier repair to combat dryness and flakiness. Allantoin and Panthenol further soothe and support skin recovery, enhancing overall comfort.
- The formulation is highly compatible with dry skin types, offering emollient action and strengthening the skin barrier.
- The product is safe for your skin, containing no harsh or irritating ingredients.
How to apply
- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
People Say
★4.8Overall rating based on 3.5k+ reviewsThis ampoule is widely celebrated for repairing damaged skin barriers and soothing irritation, particularly for dry, sensitive, or mature skin types. Users consistently praise its rich, milky texture that provides deep hydration and a radiant glow without a sticky residue. However, it is often deemed too heavy for oily skin or humid weather. This summary is based on a very large amount of data and should be definitely taken into account.
Highlights
Soothing and calming Mostly Mentioned
- “calms redness instantly”
- “comforting hug for angry barrier”
- “redness disappears overnight”
Deeply moisturizing Often Mentioned
- “skin has never felt so hydrated”
- “hydration fiesta”
- “plump and nourish the skin”
- “moisturizing enough to skip cream”
Luxurious texture Often Mentioned
- “milky but non-sticky”
- “absorbs like a dream”
- “smooth and silky finish”
- “leaves skin baby soft”
Barrier repair Sometimes Noted
- “heals moisture barrier faster”
- “restored my damaged barrier”
- “skin feels more resilient”
- “great for retinol users”
Too heavy Sometimes Noted
- “too oily for combo skin”
- “good winter serum, not summer”
- “felt a bit greasy”
- “sat on top of skin”
Caused breakouts Rarely Noted
- “broke me out slightly”
- “caused small whiteheads”
- “clogged my pores”
Dropper issues Rarely Noted
- “dropper takes while to fill”
- “hard to get product out”
- “prefer an airless pump”
- “pipette struggles with thick texture”
Scent concerns Rarely Noted
- “has an earthy scent”
- “subtle botanical aroma”
- “smell is a deal breaker”
- “fermented smell”
Sources: lovi.care, iherb.com, oliveyoung.com, stylevana.com, yesstyle.com, reddit.com, and more
Questions and answers
What makes SKIN1004 Probio-cica Intensive Ampoule a great fit for dry sensitive skin?
This treatment is a great fit because Lactobacillus Centella Asiatica Extract Ferment Filtrate and ceramide NP give your skin plenty of moisture and repair its barrier to stop dryness and flakiness. Allantoin and panthenol also help calm irritation and support recovery so your skin feels much more comfortable.
Which ingredients make this ampoule a good fit for dry sensitive skin?
This ampoule is a great fit because Lactobacillus Centella Asiatica Extract Ferment Filtrate and Ceramide NP give your skin deep hydration and repair its barrier to stop dryness and flakiness. Allantoin and Panthenol also soothe and calm your skin to help it feel soft and comfortable.
What does Lactobacillus do for dry sensitive skin?
Lactobacillus helps calm dry sensitive skin and strengthens its natural barrier to reduce irritation and water loss. Using these ingredients may make your skin more resistant to daily dryness and environmental stress.
International Journal of Molecular Sciences, 2019Biochemical Society Transactions, 2021
What does Centella Asiatica Extract do for dry sensitive skin?
Centella asiatica extract helps calm dry sensitive skin by reducing irritation and improving moisture while protecting the skin barrier. Clinical studies show that regular use noticeably decreases redness and discomfort while keeping the skin soft and hydrated.
Journal of Cosmetic Dermatology, 2025Indian Journal of Pharmaceutical Sciences, 2016
Where does this ampoule go in a skincare routine for dry sensitive skin?
This ampoule goes in your evening routine, applied after your cleanser and soothing toner and before your moisturizer. Putting treatments in the evening keeps things simple and helps avoid any extra sun sensitivity.
Can I use this ampoule with retinol, and in what order?
Yes, you can use this ampoule with retinol by applying the ampoule after your retinol to help soothe dry, sensitive skin and lock in hydration. Ingredients like ceramide NP and allantoin support skin barrier recovery, making it less likely that you will experience irritation.
How often should I use this ampoule?
You can use this ampoule in your evening routine, applying it after your toner and before your moisturizer. It is safe for daily use on dry and sensitive skin, helping to calm dryness and keep the skin feeling soft and comfortable.
Can this ampoule clog pores, cause breakouts or purging for dry sensitive skin?
This ampoule is unlikely to cause breakouts or clog pores on dry sensitive skin since it is safe and free of harsh ingredients, though a few reviewers have occasionally mentioned heaviness. It helps soothe and hydrate your skin without irritation.
What the research says
A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin.
Skin Pharmacology and Physiology, 2022Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.
The Journal of Dermatological Treatment, 2017A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment.
Journal of Cosmetic Dermatology, 2025Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.
Journal of Alternative and Complementary Medicine, 2020A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.
Auris, Nasus, Larynx, 2020A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo.
Skinmed, 2021
Ingredients
Lactobacillus Centella Asiatica Extract Ferment Filtrate, Centella Asiatica Extract, Ceramide Np, Polyhydroxystearic Acid, Betaine, Allantoin, Panthenol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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