Paula's Choice Pore Normalizing Cleanser for dry skin

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Questions and answers

What the research says

• Sodium lauroyl sarcosinate in facial cleanser decreased prokaryotic microbial alpha diversity, altered prokaryotic microbiome structure, increased phosphatidylglycerol and phosphatidylcholine, and decreased ceramides on facial skin.

  Journal of Cosmetic Dermatology, 2024

• Treatment with sodium lauryl ether sulfate emulsion increased transepidermal water loss and skin surface pH while reducing stratum corneum hydration and natural moisturizing factor content compared to diacyl phospholipid emulsions and controls, irrespective of UVA irradiation, in eight healthy volunteers.

  International Journal of Pharmaceutics, 2026

• Skin irritation potential of surfactant mixtures in 13 human subjects was dose dependent, with the highest irritation observed in formulations containing sodium laureth sulfate, lauryl glucoside, and cocamide DEA together.

  International Journal of Cosmetic Science, 1999

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.

  The Journal of Dermatological Treatment, 2017

• Sodium dodecyl sulfate (SDS) treatment decreases lipid membrane chain conformational order and stiffness leading to increased water sorption and diffusivity, whereas sodium lauryl ether sulfate (SLES) treatment increases lipid membrane conformational order and stiffness with increased water sorption capacity driven by its hygroscopic nature.

  Langmuir, 2014

• The cytotoxic effect of sodium lauryl sulphate on normal human keratinocytes was significantly decreased when combined with cocamidopropyl betaine, Tween 20, and Tween 80 at concentrations well below the critical micelle concentration.

  Skin Pharmacology and Applied Skin Physiology, 2003

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.

  Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016

• A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.

  Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020

• An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.

  Aesthetic Plastic Surgery, 2018

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.

  Arzneimittel-Forschung, 2000

• Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.

  Auris, Nasus, Larynx, 2020

Ingredients

Water, Sodium Laureth Sulfate, Sodium Lauroyl Sarcosinate, Cocamidopropyl Betaine, Glycerin, Sodium Chloride, Peg-200 Hydrogenated Glyceryl Palmate, Peg-7 Glyceryl Cocoate, Sodium Benzoate, Citric Acid, Allantoin, Panthenol, Chamomilla Recutita Flower Extract, Aloe Barbadensis Leaf Juice, Sodium Hydroxide, Tetrasodium Edta, Phenoxyethanol, Ethylhexylglycerin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.