ISDIN and Trilogy are two established skincare brands recognized for their thoughtfully formulated remedies. The Spanish brand ISDIN, founded in 1975 and owned by Puig, offers elegant moisturizers, advanced sunscreens, restorative serums, and targeted eye products that suit dry skin and sensitive skin best with reliable daily support. Meanwhile, Trilogy is deeply loved for its thoughtful moisturizers and gentle cleansers built on high-performing formulas that suit dry, balanced, and sensitive skin types best. While both provide gentle comfort and dependable protection through carefully crafted solutions, they differ in their specific offerings, with the former featuring standout items like Fusion Water, Eryfotona Actinica, and K-Ox Eyes, and the latter featuring the Vitamin C Ceramide Night Cream, Rosehip Cream Cleanser, and Line Smoothing Day Cream to address various concerns.
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
This page compares some of the most popular ISDIN and Trilogy products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
“Nothing irritated my skin — Trilogy Line Smoothing Day Cream”
+Makeup performanceOften MentionedNot noted
“acts like a primer — ISDIN Eryfotona Actinica”
“My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
“Great under makeup — ISDIN Hyaluronic Concentrate”
–Fragrance and scent issuesOften MentionedSometimes Noted
“If you are sensitive to fragrances, you might find it irritating — Trilogy Rosehip Cream Cleanser”
“Scent is awful — Trilogy Line Smoothing Day Cream”
“smell is overpowering — ISDIN Eryfotona Actinica”
–High price point and valueOften MentionedRarely Noted
“Price to be high relative to performance — Trilogy Rosehip Cream Cleanser”
“very expensive — ISDIN Eryfotona Actinica”
–Too thick or heavyNot notedOften Mentioned
“A little bit too thick — Trilogy Vitamin C Ceramide Night Cream”
Questions and answers
ISDIN or Trilogy: which is better?
ISDIN does better for lightweight textures, makeup performance, and sensitive skin, while Trilogy does better for deep moisture and hydration. However, ISDIN products on this page have a high price point and some carry strong fragrance.
What is the difference between ISDIN and Trilogy?
ISDIN offers a Lovi fit level of High for lightweight, makeup-friendly sunscreens, while Trilogy provides hydrating and brightening moisturizers like its Vitamin C Ceramide Night Cream. However, reviewers note that Trilogy has more formulation complaints and high price concerns compared to ISDIN.
ISDIN or Trilogy: which moisturizer is better?
For moisturizers on this page, Trilogy does better for hydrating formulas and deep moisture, while ISDIN is noted for lightweight and non-greasy textures. Topical hyaluronic acid helps improve skin quality and signs of aging.
Reviewers note that Trilogy tends to have a high price point and value issues, while ISDIN products on this page are also frequently described as having a high price point.
Which causes fewer breakouts, ISDIN or Trilogy?
ISDIN is rated High for acne-prone skin across several products on this page, whereas Trilogy's products on this page are mostly rated Average for acne-prone skin. This suggests that ISDIN helps prevent breakouts more reliably.
Which brand has more products that are fragrance-free, ISDIN or Trilogy?
ISDIN has more products that are fragrance-free on this page, with 3 out of 8 products listing no fragrance compared to Trilogy's 1 out of 3. Reviewers note that some products from both brands contain fragrance, but ISDIN offers a larger overall selection.
How do the morning and evening routines for dry skin compare between the two brands?
ISDIN offers a detailed morning and evening routine for dry skin featuring multiple targeted steps and sunscreen, whereas Trilogy has no brand-focused routine listed for dry skin.
What specific skin types do ISDIN's brand-focused routines best fit?
According to the brand-focused routines on this page, ISDIN best fits dry skin, sensitive skin, and mature skin.
Ceramide iii · Skin Pharmacology and Physiology, 2026
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.