ISDIN and Trilogy are two esteemed skincare brands known for their thoughtful moisturizers, serums, sunscreens, and cleansers. The Spanish brand relies on sophisticated formulas that suit acne-prone and combination skin best, while the other features high-performing formulations tailored for dry, balanced, and sensitive complexions. Both nurture the skin with reliable efficacy, though they differ primarily in their specific target audiences and heritage.
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
This page compares some of the most popular ISDIN and Trilogy products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
“Nothing irritated my skin — Trilogy Line Smoothing Day Cream”
+Makeup performanceOften MentionedNot noted
“acts like a primer — ISDIN Eryfotona Actinica”
“My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
“Great under makeup — ISDIN Hyaluronic Concentrate”
–Fragrance and scent issuesOften MentionedSometimes Noted
“If you are sensitive to fragrances, you might find it irritating — Trilogy Rosehip Cream Cleanser”
“Scent is awful — Trilogy Line Smoothing Day Cream”
“smell is overpowering — ISDIN Eryfotona Actinica”
–High price point and valueOften MentionedRarely Noted
“Price to be high relative to performance — Trilogy Rosehip Cream Cleanser”
“very expensive — ISDIN Eryfotona Actinica”
–Too thick or heavyNot notedOften Mentioned
“A little bit too thick — Trilogy Vitamin C Ceramide Night Cream”
Questions and answers
ISDIN or Trilogy: which is better?
ISDIN does better for sensitive skin and makeup performance with its lightweight, non-greasy sunscreens, while Trilogy is preferred for hydrating formulas and deep moisture. However, reviewers note that Trilogy has more fragrance and price issues, and ISDIN products on this page can sometimes feel too thick or heavy.
What is the difference between ISDIN and Trilogy?
ISDIN offers ultralight sunscreens and lightweight moisturizers that Lovi rates as sensitive-skin friendly, whereas Trilogy provides hydrating and brightening moisturizers with deeper moisture.
ISDIN or Trilogy: which moisturizer is better?
When it comes to moisturizers, Trilogy offers products on this page that reviewers mostly mention for providing hydrating and brightening benefits, whereas ISDIN features options like Hyaluronic Concentrate with a Lovi fit level of Average for dry skin. Trilogy products on this page lean toward deep moisture, though reviewers note some formulation complaints.
Reviewers note that both ISDIN and Trilogy have a high price point, but Trilogy faces more complaints about high price and value among the products on this page.
Which causes fewer breakouts, ISDIN or Trilogy?
ISDIN fits acne-prone skin better than Trilogy, as ISDIN has multiple products featuring High Lovi fit levels for acne-prone skin, including Eryfotona Actinica, Fusion Water, and Retinal Intense Serum. Trilogy's products on this page only reach an Average Lovi fit level for acne-prone skin.
Between ISDIN and Trilogy, which brand offers better options for sensitive skin?
ISDIN offers better options for sensitive skin, as Lovi rates its sensitive skin fit as sensitive skin friendly and reviewers mostly mention its skin-friendly sunscreens.
How do the founding years and corporate ownership of ISDIN and Trilogy compare?
ISDIN was founded in 1975 in Spain and is owned by Puig, whereas Trilogy was founded in 2002 and has been owned by CITIC Capital Holdings Limited since 2018.
Which brand has more complaints regarding fragrance and product formulation, ISDIN or Trilogy?
Trilogy does better in hydrating formulas and deep moisture, but it receives more complaints regarding fragrance and product formulation. ISDIN is better for sensitive skin and makeup performance, though reviewers note a high price point.
Ceramide iii · Skin Pharmacology and Physiology, 2026
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
