ISDIN and Trilogy are two established skincare brands recognized for their thoughtfully formulated remedies. The Spanish brand ISDIN, founded in 1975 and owned by Puig, offers elegant moisturizers, advanced sunscreens, restorative serums, and targeted eye products that suit dry skin and sensitive skin best with reliable daily support. Meanwhile, Trilogy is deeply loved for its thoughtful moisturizers and gentle cleansers built on high-performing formulas that suit dry, balanced, and sensitive skin types best. While both provide gentle comfort and dependable protection through carefully crafted solutions, they differ in their specific offerings, with the former featuring standout items like Fusion Water, Eryfotona Actinica, and K-Ox Eyes, and the latter featuring the Vitamin C Ceramide Night Cream, Rosehip Cream Cleanser, and Line Smoothing Day Cream to address various concerns.
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
This page compares some of the most popular ISDIN and Trilogy products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
“Nothing irritated my skin — Trilogy Line Smoothing Day Cream”
+Makeup performanceOften MentionedNot noted
“acts like a primer — ISDIN Eryfotona Actinica”
“My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
“Great under makeup — ISDIN Hyaluronic Concentrate”
–Fragrance and scent issuesOften MentionedSometimes Noted
“If you are sensitive to fragrances, you might find it irritating — Trilogy Rosehip Cream Cleanser”
“Scent is awful — Trilogy Line Smoothing Day Cream”
“smell is overpowering — ISDIN Eryfotona Actinica”
–High price point and valueOften MentionedRarely Noted
“Price to be high relative to performance — Trilogy Rosehip Cream Cleanser”
“very expensive — ISDIN Eryfotona Actinica”
–Too thick or heavyNot notedOften Mentioned
“A little bit too thick — Trilogy Vitamin C Ceramide Night Cream”
Questions and answers
ISDIN or Trilogy: which is better?
ISDIN is better for lightweight textures, sensitive skin, and makeup-friendly sunscreens among the products on this page, while Trilogy is better for deep moisture and hydration. Antioxidants help protect against skin damage, and vitamin C may improve skin brightness and signs of aging.
ISDIN brings a lightweight, non-greasy texture and suits sensitive skin well with its ultralight sunscreens, while Trilogy tends to offer deeper moisture and hydrating formulas but has more fragrance issues. Lovi gives ISDIN fit levels of Superior for dry sensitive skin and acne-prone skin, and Trilogy fit levels of High for sensitive skin.
ISDIN or Trilogy: which moisturizer is better?
ISDIN is better for lightweight moisture, while Trilogy is better for deep hydration and brightening. For moisturizers on this page, ISDIN has an average fit for dry skin, and Trilogy has a high fit for dry skin.
Which is more affordable, ISDIN or Trilogy?
Trilogy is often noted by reviewers for a high price point and value, while ISDIN also faces complaints about a high price point.
Which causes fewer breakouts, ISDIN or Trilogy?
For acne-prone skin, both brands offer products on this page with High Lovi fit levels, such as ISDIN Eryfotona Actinica and Trilogy Rosehip Cream Cleanser. Topical ingredients like vitamin C in products such as Flavo-C Serum help manage breakouts and skin health.
Which brand has more fragrance-free options, ISDIN or Trilogy?
ISDIN has more fragrance-free options than Trilogy, with 3 of its 8 products on this page listing no fragrance compared to 1 of 3 for Trilogy.
How do the founding years and corporate ownerships of ISDIN and Trilogy compare?
ISDIN was founded earlier in 1975 in Spain and is owned by Puig, whereas Trilogy was founded later in 2002 and has been owned by CITIC Capital Holdings Limited since 2018.
Which sunscreen brand is better rated for makeup-friendliness, ISDIN or Trilogy?
ISDIN is better rated for makeup-friendliness, as the products on this page are mostly mentioned by reviewers for being makeup-friendly sunscreens. Trilogy does not feature sunscreens on this page.
Ceramide iii · Skin Pharmacology and Physiology, 2026
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.