Cetaphil vs Simple
Cetaphil and Simple are trusted drugstore brands offering gentle, everyday formulations designed for delicate complexions. The American heritage line favors glycerin, niacinamide, and panthenol to support dry, sensitive, and acne-prone skin through nourishing cleansers, moisturizers, and targeted serums. Meanwhile, the British counterpart relies on niacinamide and glycerin within soothing moisturizers, makeup removers, cleansers, and toners tailored for oily and acne-prone skin. While both share a devotion to barrier-supporting ingredients, they differ in their specific botanical focus and geographic origins.
Cetaphil is an American skincare brand founded in 1947 and owned by Galderma Group AG.
en.wikipedia.orgcetaphil.co.uk
Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.
en.wikipedia.orgsec.govprnewswire.comsimple.co.uk
This page compares some of the most popular Cetaphil and Simple products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Cetaphil vs Simple products
People Say
Gentle on sensitive skin Mostly MentionedMostly Mentioned
- “The only thing my reactive skin tolerates. — Cetaphil Gentle Skin Cleanser”
- “No breakouts since switching to this. — Cetaphil Gentle Skin Cleanser”
- “Does not cause any form of irritation on the skin which I love. — Simple Micellar Cleansing Water”
- “The only cleanser that doesn't turn my face red. — Simple Micellar Water”
Hydration and moisture Mostly MentionedMostly Mentioned
- “cleared up flaky skin — Cetaphil Moisturizing Cream”
- “healed my dry patches — Cetaphil Moisturising Cream”
- “banished dryness within days — Simple Replenishing Rich Moisturiser”
- “Instantly boosts skin's hydration... face doesn't feel dry and tight. — Simple Micellar Cleansing Water”
Texture and weight Often MentionedOften Mentioned
- “absorbs instantly — Cetaphil Moisturizing Lotion”
- “Absorbs quickly into skin without residue — Cetaphil Daily Hydrating Lotion”
- “sinks in instantly — Simple Water Boost Hydrating Gel Cream”
- “absorbs very quickly — Simple Hydrating Light Moisturiser”
Dermatologist and value praise Rarely NotedOften Mentioned
- “great value for money — Simple Kind to Skin Soothing Facial Toner”
- “super affordable — Simple Hydrating Light Moisturiser”
- “Can't beat the price for the quality. — Simple Micellar Water”
- “recommended by my derm — Cetaphil Daily Facial Cleanser”
Versatile use and application Often MentionedSometimes Noted
- “great for face and body — Cetaphil Moisturizing Cream”
- “removes excess oil — Cetaphil Daily Facial Cleanser”
- “Takes off any makeup residue and makes my face feel refreshed. — Simple Micellar Cleansing Water”
- “Best morning cleanser — Simple Refreshing Facial Wash”
Fragrance-free and scent issues Sometimes NotedOften Mentioned
- “Love that it has absolutely no scent. — Simple Micellar Water”
- “love that it's alcohol-free — Simple Kind to Skin Soothing Facial Toner”
- “No strong smell — Simple Refreshing Facial Wash”
- “truly no smell — Cetaphil Moisturizing Lotion”
Makeup removal difficulties Sometimes NotedOften Mentioned
- “Doesn't take off mascara at all. — Cetaphil Gentle Skin Cleanser”
- “doesn't remove mascara — Cetaphil Daily Facial Cleanser”
- “Struggles with mascara. — Cetaphil Oily Skin Cleanser”
- “Did not remove my mascara very well at all. — Simple Micellar Cleansing Water”
Dryness and lack of moisture Sometimes NotedSometimes Noted
- “Felt a little stripping on sensitive areas. — Cetaphil Oily Skin Cleanser”
- “Skin felt dehydrated after 30 minutes — Cetaphil Daily Hydrating Lotion”
- “not moisturizing enough — Simple Hydrating Light Moisturiser”
- “skin felt tight after an hour — Simple Water Boost Hydrating Gel Cream”
Formula changes and irritation Sometimes NotedSometimes Noted
- “New bottle ingredients do not match... lower amounts of beneficial ingredients. — Simple Micellar Cleansing Water”
- “new formula stings — Simple Replenishing Rich Moisturiser”
- “burned upon application — Simple Water Boost Hydrating Gel Cream”
- “New version burns my face. — Cetaphil Gentle Skin Cleanser”
Cetaphil vs Simple routines for dry skin
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Cleanser
Refreshing Facial Wash
Morning · Evening · Once a week
AED 24.78
-
Moisturizer
Replenishing Rich Moisturiser
Morning · Evening · Once a week
AED 11.84
-
SPF
Dr.G Green Mild Up Sun+
Morning
AED 81.00
-
Pre-Cleanser
Micellar Cleansing Water
Evening · Once a week
AED 17.15
-
Cleansing Toner
ROUND LAB 1025 Dokdo Cleansing Water
Evening
AED 38.99
-
Serum or Treatment
Peach & Lily Glass Skin Refining Serum
Evening · Once a week
AED 168.76
-
Enzyme Powder
VT Cica Mild Powder Wash
Once a week
AED 47.62
-
Nourishing Mask
Mediheal Watermide Essential Mask
Once a week
AED 65.00
-
Cleanser
Gentle Skin Cleanser
Morning · Evening · Once a week
AED 44.60
-
Hydrating Toner
Healthy Radiance Brightness Refresh Toner
Morning
AED 79.00
-
Moisturizer
Rich Hydrating Night Cream
Morning · Evening · Once a week
AED 50.00
-
SPF
Daily Facial Moisturizer
Morning
AED 84.00
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
AED 35.29
-
Cleansing Toner
ROUND LAB 1025 Dokdo Cleansing Water
Evening
AED 38.99
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
AED 88.43
-
Enzyme Powder
VT Cica Mild Powder Wash
Once a week
AED 47.62
-
Nourishing Mask
Mediheal Watermide Essential Mask
Once a week
AED 65.00
Buy Simple routine · AED 455.14 · 83% fit
Buy Cetaphil routine · AED 319.93 · 82% fitSee multi-brand routine · 96% fit
Cetaphil vs Simple routines for oily skin
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Cleanser
Refreshing Facial Wash
Morning · Evening · Once a week
AED 24.78
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
AED 49.99
-
Moisturizer
Replenishing Rich Moisturiser
Morning · Evening · Once a week
AED 11.84
-
SPF
d'Alba UVessence Mild Waterfull Sun Cream SPF 50
Morning
AED 92.70
-
Pre-Cleanser
Micellar Cleansing Water
Evening · Once a week
AED 17.15
-
Cleansing Toner
Pixi Glow Tonic
Evening
AED 120.00
-
Serum or Treatment
Peach & Lily Glass Skin Refining Serum
Evening · Once a week
AED 168.76
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
Revision Skincare Black Mask
Once a week
AED 204.00
-
Cleanser
Oily Skin Cleanser
Morning · Evening · Once a week
AED 54.95
-
Hydrating Toner
Healthy Radiance Brightness Refresh Toner
Morning · Once a week
AED 79.00
-
Moisturizer
Daily Hydrating Lotion
Morning · Evening · Once a week
AED 81.00
-
SPF
Oil Control
Morning
AED 25.69
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
AED 179.45
-
Cleansing Toner
Pixi Glow Tonic
Evening
AED 120.00
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
AED 88.43
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
Revision Skincare Black Mask
Once a week
AED 204.00
Buy Simple routine · AED 790.31 · 88% fit
Buy Cetaphil routine · AED 854.61 · 81% fitSee multi-brand routine · 97% fit
Cetaphil vs Simple routines for combination skin
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Cleanser
Refreshing Facial Wash
Morning · Evening · Once a week
AED 24.78
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
AED 145.00
-
Moisturizer
Replenishing Rich Moisturiser
Morning · Evening · Once a week
AED 11.84
-
Pre-Cleanser
Micellar Cleansing Water
Evening · Once a week
AED 17.15
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
AED 53.12
-
Serum or Treatment
Peach & Lily Glass Skin Refining Serum
Evening · Once a week
AED 168.76
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
KORA Organics Turmeric Brightening & Exfoliating Mask
Once a week
AED 122.93
-
Cleanser
Oily Skin Cleanser
Morning · Evening · Once a week
AED 54.95
-
Hydrating Toner
Healthy Radiance Brightness Refresh Toner
Morning · Once a week
AED 79.00
-
Moisturizer
Daily Hydrating Lotion
Morning · Evening · Once a week
AED 81.00
-
SPF
Oil Control
Morning
AED 25.69
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
AED 179.45
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
AED 53.12
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
AED 88.43
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
KORA Organics Turmeric Brightening & Exfoliating Mask
Once a week
AED 122.93
Buy Simple routine · AED 644.67 · 85% fit
Buy Cetaphil routine · AED 706.66 · 82% fitSee multi-brand routine · 96% fit
Questions and answers
Cetaphil or Simple: which is better?
Both brands offer an equal routine fit for all skin types, including dry, oily, and sensitive skin. Niacinamide helps reduce cutaneous pigmentation and skin aging.
What is the difference between Cetaphil and Simple?
Both brands offer fragrance-free options and achieve equal Lovi routine fit levels across all skin types, but they differ in their product selection and ingredient variety. Cetaphil features a broader range with key ingredients like glycerin, niacinamide, panthenol, vitamin E, hyaluronic acid, and cocamidopropyl betaine, while Simple focuses on simpler formulations with niacinamide and glycerin.
Cetaphil or Simple for dry skin?
Both brands achieve a High routine fit for dry skin on Lovi. Cetaphil features key ingredients like glycerin and hyaluronic acid, which help maintain skin hydration and improve skin quality.
Cetaphil or Simple: which cleanser is better?
Both Cetaphil and Simple offer gentle cleansers that achieve a High routine fit for sensitive skin. Cetaphil features specialized options like the Gentle Skin Cleanser that achieve a Superior fit for dry sensitive skin.
Which is more affordable, Cetaphil or Simple?
Simple stands out for its value-friendly moisturizers, while the products on this page for both brands offer comparable routine fit levels across different skin types.
Which brand has more products containing fragrance, Cetaphil or Simple?
Cetaphil has more products containing fragrance, as 26 of 27 products on this page list no fragrance while the Oily Skin Cleanser contains it, whereas every product on the Simple page lists no fragrance.
Which brand offers better dermatologist and value praise, Cetaphil or Simple?
Simple does better for dermatologist and value praise. Reviewers note its lightweight, value-friendly moisturizers and gentle makeup removers.
Which company is older and where was it founded, Cetaphil or Simple?
Cetaphil is older than Simple, having been founded in the United States in 1947, while Simple was founded in the United Kingdom in 1960.
Cetaphil or Simple for oily skin?
Both brands are a good choice for oily skin, with Lovi fit levels reaching High for both Cetaphil and Simple. Niacinamide, found in the products on this page, helps control skin aging and pigmentation.
Cetaphil or Simple: which moisturizer is better?
Both Cetaphil and Simple offer options for moisturizers, and the products on this page achieve equal fit levels across various skin types. Niacinamide, found in the moisturizers of both brands, helps reduce cutaneous pigmentation.
Cetaphil or Simple for sensitive skin?
Both brands achieve a High routine fit for sensitive skin on Lovi. Cetaphil features gentle, non-stripping cleansers while Simple offers gentle, sensitive-skin-friendly makeup removers.
Cetaphil or Simple for acne-prone skin?
Both brands are a High fit for acne-prone skin, with Cetaphil offering specialized options like the Ceramide Serum and Gentle Exfoliating SA Cleanser. Niacinamide, a key ingredient found in the products on this page, may help control skin pigmentation and aging.
Research behind their key ingredients
Effects of menthol and cold on histamine-induced itch and skin reactions in man
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin
Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Colloidal Oatmeal <em>(Avena Sativa)</em> Improves Skin Barrier Through Multi-Therapy Activity
The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome
Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Modulating effects of oatmeal extracts in the sodium lauryl sulfate skin irritancy model
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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