Cetaphil vs Simple
Cetaphil and Simple are heritage drugstore labels known for thoughtful, barrier-supporting staples centered on glycerin and niacinamide. The American line, founded in 1947, leans toward rich lotions and targeted serums suited for combination, acne-prone, and mature complexions, while the British range, established in 1960, favors lightweight waters and cleansers ideal for oily and blemish-prone skin. Both brands deliver proven hydration and soothing benefits, though they differ in their national origins, parent companies, and specific textural approaches to sensitive daily care.
Cetaphil is an American skincare brand founded in 1947 and owned by Galderma Group AG.
en.wikipedia.orgcetaphil.co.uk
Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.
en.wikipedia.orgsec.govprnewswire.comsimple.co.uk
This page compares some of the most popular Cetaphil and Simple products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Cetaphil vs Simple products
People Say
Gentle on sensitive skin Mostly MentionedMostly Mentioned
- “The only thing my reactive skin tolerates. — Cetaphil Gentle Skin Cleanser”
- “No breakouts since switching to this. — Cetaphil Gentle Skin Cleanser”
- “Does not cause any form of irritation on the skin which I love. — Simple Micellar Cleansing Water”
- “The only cleanser that doesn't turn my face red. — Simple Micellar Water”
Hydration and moisture Mostly MentionedMostly Mentioned
- “cleared up flaky skin — Cetaphil Moisturizing Cream”
- “healed my dry patches — Cetaphil Moisturising Cream”
- “banished dryness within days — Simple Replenishing Rich Moisturiser”
- “Instantly boosts skin's hydration... face doesn't feel dry and tight. — Simple Micellar Cleansing Water”
Texture and weight Often MentionedOften Mentioned
- “absorbs instantly — Cetaphil Moisturizing Lotion”
- “Absorbs quickly into skin without residue — Cetaphil Daily Hydrating Lotion”
- “sinks in instantly — Simple Water Boost Hydrating Gel Cream”
- “absorbs very quickly — Simple Hydrating Light Moisturiser”
Dermatologist and value praise Rarely NotedOften Mentioned
- “great value for money — Simple Kind to Skin Soothing Facial Toner”
- “super affordable — Simple Hydrating Light Moisturiser”
- “Can't beat the price for the quality. — Simple Micellar Water”
- “recommended by my derm — Cetaphil Daily Facial Cleanser”
Versatile use and application Often MentionedSometimes Noted
- “great for face and body — Cetaphil Moisturizing Cream”
- “removes excess oil — Cetaphil Daily Facial Cleanser”
- “Takes off any makeup residue and makes my face feel refreshed. — Simple Micellar Cleansing Water”
- “Best morning cleanser — Simple Refreshing Facial Wash”
Fragrance-free and scent issues Sometimes NotedOften Mentioned
- “Love that it has absolutely no scent. — Simple Micellar Water”
- “love that it's alcohol-free — Simple Kind to Skin Soothing Facial Toner”
- “No strong smell — Simple Refreshing Facial Wash”
- “truly no smell — Cetaphil Moisturizing Lotion”
Makeup removal difficulties Sometimes NotedOften Mentioned
- “Doesn't take off mascara at all. — Cetaphil Gentle Skin Cleanser”
- “doesn't remove mascara — Cetaphil Daily Facial Cleanser”
- “Struggles with mascara. — Cetaphil Oily Skin Cleanser”
- “Did not remove my mascara very well at all. — Simple Micellar Cleansing Water”
Dryness and lack of moisture Sometimes NotedSometimes Noted
- “Felt a little stripping on sensitive areas. — Cetaphil Oily Skin Cleanser”
- “Skin felt dehydrated after 30 minutes — Cetaphil Daily Hydrating Lotion”
- “not moisturizing enough — Simple Hydrating Light Moisturiser”
- “skin felt tight after an hour — Simple Water Boost Hydrating Gel Cream”
Formula changes and irritation Sometimes NotedSometimes Noted
- “New bottle ingredients do not match... lower amounts of beneficial ingredients. — Simple Micellar Cleansing Water”
- “new formula stings — Simple Replenishing Rich Moisturiser”
- “burned upon application — Simple Water Boost Hydrating Gel Cream”
- “New version burns my face. — Cetaphil Gentle Skin Cleanser”
Cetaphil vs Simple routines for dry skin
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Cleanser
Gentle Skin Cleanser
Morning · Evening · Once a week
€15.19
-
Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
€12.59
-
Moisturizer
Rich Hydrating Night Cream
Morning · Evening · Once a week
€22.42
-
SPF
Sheer Mineral Sunscreen SPF 50
Morning
€30.12
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€10.97
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
€15.59
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
€19.00
-
Cleanser
Refreshing Facial Wash
Morning · Evening · Once a week
€14.98
-
Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
€12.59
-
Moisturizer
Replenishing Rich Moisturiser
Morning · Evening · Once a week
€9.87
-
SPF
Australian Gold Botanical Lotion SPF 30
Morning
€21.04
-
Pre-Cleanser
Micellar Cleansing Water
Evening · Once a week
€9.87
-
Serum or Treatment
Beauty of Joseon Propolis + Niacinamide Glow Serum
Evening · Once a week
€9.99
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
€19.00
Cetaphil vs Simple routines for oily skin
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Cleanser
Daily Facial Cleanser
Morning · Evening · Once a week
€24.59
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€16.59
-
Moisturizer
Ceramide Serum
Morning · Evening · Once a week
€39.77
-
SPF
Oil Control
Morning
€23.48
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€104.00
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
€16.90
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
€15.59
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Dr. Sebagh Deep Exfoliating Mask
Once a week
€81.80
-
Cleanser
Refreshing Facial Wash
Morning · Evening · Once a week
€14.98
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€16.59
-
Moisturizer
Replenishing Rich Moisturiser
Morning · Evening · Once a week
€9.87
-
SPF
make p:rem UV Defense Me Blue Ray Sun Cream
Morning
€32.80
-
Pre-Cleanser
Micellar Cleansing Water
Evening · Once a week
€9.87
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
€16.90
-
Serum or Treatment
The Ordinary Niacinamide 10% + Zinc 1%
Evening · Once a week
€5.80
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Dr. Sebagh Deep Exfoliating Mask
Once a week
€81.80
Cetaphil vs Simple routines for combination skin
-
Cleanser
Daily Facial Cleanser
Morning · Evening · Once a week
€24.59
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Ceramide Serum
Morning · Evening · Once a week
€39.77
-
SPF
Sheer Mineral Sunscreen SPF 50
Morning
€30.12
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€104.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€16.98
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
€15.59
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
€28.50
-
Cleanser
Refreshing Facial Wash
Morning · Evening · Once a week
€14.98
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Replenishing Rich Moisturiser
Morning · Evening · Once a week
€9.87
-
Pre-Cleanser
Micellar Cleansing Water
Evening · Once a week
€9.87
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€16.98
-
Serum or Treatment
Beauty of Joseon Propolis + Niacinamide Glow Serum
Evening · Once a week
€9.99
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
€28.50
Questions and answers
Cetaphil or Simple: which is better?
Both Cetaphil and Simple are great choices, as both brands achieve high fit levels across most skin types on this page. Cetaphil reaches a superior routine fit for combination and acne-prone skin, while Simple offers strong dermatologist and value praise.
What is the difference between Cetaphil and Simple?
Cetaphil is a US-founded brand offering a wider variety of specialized products with a Lovi fit level of Superior for combination and acne-prone skin, whereas Simple is a UK-founded brand known for its value-friendly moisturizers and sensitive-skin-friendly makeup removers. Both brands generally feature fragrance-free formulations and include key ingredients like glycerin and niacinamide.
Cetaphil or Simple for dry skin?
Both brands offer an equal routine fit for dry skin with a High level. Cetaphil products on this page include key ingredients like hyaluronic acid and glycerin, which may help improve skin hydration.
Cetaphil or Simple: which cleanser is better?
Both Cetaphil and Simple offer gentle cleansers, but Cetaphil achieves a Superior fit level for specific skin needs like dry and oily skin with cleansers such as the Gentle Skin Cleanser and Daily Facial Cleanser. Reviewers mention that Cetaphil cleansers are gentle and non-stripping.
Which is more affordable, Cetaphil or Simple?
Simple does better for dermatologist and value praise on the products on this page. Niacinamide helps reduce cutaneous pigmentation.
Which brand has better fragrance-free options, Cetaphil or Simple?
Simple does better on fragrance-free and scent issues. The products on this page for Simple list no fragrance in every single item, while Cetaphil includes a fragrance in its Oily Skin Cleanser.
Cetaphil or Simple for oily skin?
Both brands offer a High routine fit for oily skin. The products on this page help provide gentle cleansing and lightweight moisture.
Cetaphil or Simple: which moisturizer is better?
Both Cetaphil and Simple offer products on this page with an average routine fit for dry skin. Cetaphil contains key ingredients like niacinamide and glycerin, which may help improve skin hydration and barrier function.
Cetaphil or Simple for sensitive skin?
Both Cetaphil and Simple are great options, as Lovi gives them an equal High fit level for sensitive skin. Niacinamide, which is found in both brands, helps control skin aging and pigmentation.
Cetaphil or Simple for acne-prone skin?
Cetaphil is the better choice for acne-prone skin because Lovi rates its routine fit as Superior, whereas Simple is High. Reviewers mostly mention Cetaphil for gentle, non-stripping cleansers and hydrating, non-greasy moisturizers across the products on this page.
Cetaphil or Simple for combination skin?
Cetaphil is the better choice for combination skin, offering a Superior routine fit compared to Simple's High fit.
Cetaphil or Simple for mature skin?
Cetaphil has a High Lovi fit for mature skin, while Simple also has a High Lovi fit for mature skin. Both brands feature key ingredients like niacinamide and glycerin, which help support skin hydration and reduce signs of aging.
Research behind their key ingredients
Effects of menthol and cold on histamine-induced itch and skin reactions in man
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin
Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Colloidal Oatmeal <em>(Avena Sativa)</em> Improves Skin Barrier Through Multi-Therapy Activity
The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome
Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Modulating effects of oatmeal extracts in the sodium lauryl sulfate skin irritancy model
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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