COSRX The 6 Peptide Skin Booster Serum for oily acne-prone skin
Sodium Hyaluronate
Peptides
N-Acetyl Glucosamine
Niacinamide
AllantoinHigh
- HighOily Skin Fit
- HighEffectiveness
- ExcellentSafety
A great choice for oily acne-prone skin; a few moisturizers fit it even better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your oily skin, this serum effectively addresses acne and breakouts with niacinamide for oil control and inflammation reduction, complemented by acetyl hexapeptide-8 to hydrate and minimize fine lines.
- The inclusion of multiple peptides like copper tripeptide-1 and sh-polypeptide-121 further supports skin health and anti-aging benefits, enhancing overall skin appearance.
- The product boasts an excellent safety profile, with soothing ingredients like tocopherol and allantoin ensuring no irritation for your oily skin.
How to apply
- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
People Say
★4.7Overall rating based on 5.4k+ reviewsBased on a very large amount of data, users consistently praise this serum as a lightweight, water-like "booster" that significantly improves skin texture and hydration without heaviness. It is widely celebrated for smoothing pores and creating a "glass skin" glow. A small minority of users with specific sensitivities experienced breakouts or closed comedones.
Highlights
Lightweight & fast-absorbing Mostly Mentioned
- “absorbs instantly like water”
- “non-sticky finish”
- “perfect for layering”
- “feels weightless on oily skin”
Hydrating & plumping Often Mentioned
- “gives a healthy glow”
- “skin feels plump”
- “boosts hydration levels”
- “glass skin effect”
Improves skin texture Often Mentioned
- “skin feels softer immediately”
- “smoothed out my texture”
- “pores look smaller”
- “reduced roughness”
Gentle & non-irritating Sometimes Noted
- “no stinging on sensitive skin”
- “soothing application”
- “great for barrier repair”
- “gentle enough for daily use”
Caused breakouts Rarely Noted
- “gave me closed comedones”
- “caused tiny whiteheads”
- “broke me out after a week”
- “bad reaction for acne-prone skin”
Ingredient sensitivities Rarely Noted
- “reacted to the niacinamide”
- “contains soy oil (allergy warning)”
- “caused redness/flushing”
No visible results Rarely Noted
- “did absolutely nothing”
- “just expensive water”
- “no change in fine lines”
- “saw no difference after a bottle”
Sticky residue Rarely Noted
- “felt slightly tacky”
- “left a sticky film”
- “clashed with other products”
- “too slimy”
Sources: lovi.care, ulta.com, sokoglam.com, yesstyle.com, oliveyoung.com, amazon.com, and more
Questions and answers
What makes COSRX The 6 Peptide Skin Booster Serum a great fit for oily acne-prone skin?
This serum is a great fit because niacinamide helps control oil and calm breakouts, while multiple peptides hydrate and smooth fine lines. Soothing ingredients like allantoin ensure it is very unlikely to cause irritation on oily skin.
American Journal of Clinical Dermatology, 2013Journal of Cosmetic and Laser Therapy, 2013
Which ingredients make this serum a good fit for oily acne-prone skin?
This serum is a great fit for your oily acne-prone skin because it contains niacinamide to control oil and calm redness, along with acetyl hexapeptide-8 and copper tripeptide-1 to smooth and support skin health. Soothing ingredients like allantoin and tocopherol help ensure it stays gentle and is unlikely to cause irritation.
American Journal of Clinical Dermatology, 2013Journal of Cosmetic and Laser Therapy, 2013
What does Hyaluronic Acid do for oily acne-prone skin?
Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
The Journal of Investigative Dermatology, 2017Journal of Cosmetic Dermatology, 2022
What do Peptides do for oily acne-prone skin?
Peptides help calm oily, acne-prone skin by targeting acne-causing bacteria and reducing redness and swelling. Advanced delivery methods like nanomicelles may also improve how deeply these helpful ingredients sink into the skin.
Where does this serum go in a skincare routine for oily acne-prone skin?
This serum goes in the evening routine after cleansing and before moisturizing, as treatments with actives are placed in the evening for simplicity and extra safety. Soothing ingredients like allantoin and tocopherol help ensure this product is unlikely to cause irritation.
Can I use this serum with retinol, and in what order?
Yes, you can use this serum with retinol by applying the serum first to hydrate and soothe your skin before your retinol product. This layered approach helps manage oil and reduce breakouts while keeping your skin calm and comfortable.
How often should I use this serum?
This serum is a great fit for your oily acne-prone skin and is designed to be used in the evening routine. Applying it daily helps manage oil, soothe breakouts, and hydrate without causing irritation.
Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?
This serum is a great fit for your oily acne-prone skin and is unlikely to cause breakouts or clog pores, as it uses niacinamide to help control oil and soothe inflammation. Reviewers rarely report breakouts, and calming ingredients like allantoin help prevent irritation.
Can I use this serum around the eyes or on my body?
This moisturizing treatment is generally safe to use on the body and around the eyes, though the skin around the eyes is much thinner and more delicate than body skin. Soothing ingredients like allantoin and tocopherol help ensure a low risk of irritation.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.
American Journal of Clinical Dermatology, 2013Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects.
Journal of Cosmetic and Laser Therapy, 2013Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days.
Annals of Dermatology, 2019The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls.
Skin Research and Technology, 2026Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide.
Journal of Cosmetic Dermatology, 2007N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers.
Advanced Pharmaceutical Bulletin, 2016Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants.
Journal of Cosmetic and Laser Therapy, 2019Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018
Ingredients
Water, Dipropylene Glycol, Glycerin, Pentylene Glycol, 1,2-Hexanediol, Niacinamide, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polyacrylate Crosspolymer-6, Butylene Glycol, Xanthan Gum, Ethylhexylglycerin, Adenosine, Polyquaternium-51, Disodium Edta, Citric Acid, Caprylyl Glycol, Betaine, T-Butyl Alcohol, Sodium Pca, Sodium Lactate, Acetyl Hexapeptide-8, Copper Tripeptide-1, Pca, Sh-Polypeptide-121, Serine, Alanine, Allantoin, Sodium Hyaluronate, Acetyl Glucosamine, Glycine, Glutamic Acid, Lysine Hcl, Threonine, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Arginine, Tocopherol, Oligopeptide-68, Proline, Dextran, Palmitoyl Tripeptide-8, Glycine Soja Oil Soybean Oil, Hydrogenated Lecithin, Potassium Sorbate, Sodium Oleate
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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