Skintific and Sesderma are distinguished skincare lines known for delivering effective daily care and refined radiance through meticulously engineered formulas. The former is celebrated for its targeted moisturizers, serums, and sunscreens featuring key ingredients like ceramides and mugwort, making it best suited for oily, acne-prone, and combination skin with dark spots or signs of aging. Conversely, the Spanish brand is beloved for advanced serums utilizing botanical extracts and active compounds that gracefully address sensitive, hyperpigmented, and aging complexions. Ultimately, while both offer standout solutions like the All Day Light Sunscreen Mist and the Azelac RU Serum, they differ in their foundational approach and ideal skin types.
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
This page compares some of the most popular Skintific and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Skintific is better for everyday hydration and sun protection, as the products on this page list no fragrance, whereas Sesderma includes fragrance in its serum. Lovi gives Skintific high ratings for dry skin and sensitive skin when using items like the All Day Light Sunscreen Mist.
What is the difference between Skintific and Sesderma?
Skintific is a newer brand founded in 2021, while Sesderma has been around since 1989 and is based in Spain. Additionally, the products on this page by Skintific list no fragrance, whereas Sesderma's Azelac RU Serum contains fragrance.
Which is more affordable, Skintific or Sesderma?
I am sorry, but the provided page facts and studies do not contain information about the pricing or affordability of Skintific and Sesderma.
Which causes fewer breakouts, Skintific or Sesderma?
Skintific is a better fit for oily acne-prone skin, as the products on this page achieve a High Lovi fit level for that skin type compared to Sesderma's Azelac RU Serum which achieves an Average Lovi fit level. Niacinamide helps reduce cutaneous pigmentation and suppresses melanosome transfer.
How do the founding years and countries of origin compare between Skintific and Sesderma?
Skintific was founded in 2021 with its country of origin not available on the page, while Sesderma was founded in 1989 in Spain.
Which brand has more fragrance-free products listed on the page, Skintific or Sesderma?
Skintific has more fragrance-free options because every product on the Skintific page lists no fragrance in its ingredients, whereas the Sesderma product on this page includes fragrance.
How does the Lovi fit level for dry skin differ between Skintific's 5X Ceramide Barrier Moisture Gel and Sesderma's Azelac RU Serum?
Lovi rates Skintific's 5X Ceramide Barrier Moisture Gel as a High fit for dry skin, whereas Sesderma's Azelac RU Serum is rated as a Low fit for dry skin.
Homosalate 路 Journal of Drugs in Dermatology, 2025
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
