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Skintific vs Sesderma

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes 路 How the Fit score works

Skintific and Sesderma are thoughtful skincare brands offering targeted moisturizers, protective sunscreens, and advanced serums. The former is loved for its comforting preparations, such as the All Day Light Sunscreen Mist, 5X Ceramide Barrier Moisture Gel, and MUGWORT, which suit dry, dry sensitive, and acne-prone skin best. Meanwhile, the Spanish brand founded in 1989 and owned by Grupo Sesderma since 2026 is beloved for meticulously engineered formulas like the Azelac RU Serum, suiting sensitive, hyperpigmented, and aging skin types. Both brands differ because the former carefully balances every component for reliable daily care, while its counterpart relies on botanical extracts and active compounds to refine skin texture and promote a radiant complexion.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Skintific and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Skintific vs Sesderma products

Questions and answers

Skintific or Sesderma: which is better?

Skintific is a better fit for dry skin, dry sensitive skin, and combination skin, with products on this page that list no fragrance. Sesderma's Azelac RU Serum carries a high fit for skin with dark spots and acne-prone skin, but contains fragrance.

What is the difference between Skintific and Sesderma?

Skintific is a newer brand founded in 2021 with products on this page listing no fragrance, whereas Sesderma was founded in 1989 in Spain and includes fragrance in its Azelac RU Serum. Skintific fits best for dry skin, dry sensitive skin, and combination skin, while Sesderma has no listed routine-focused best fits on this page.

Which is more affordable, Skintific or Sesderma?

The page facts do not provide pricing information to determine whether Skintific or Sesderma is more affordable.

Which causes fewer breakouts, Skintific or Sesderma?

Skintific is a better fit for acne-prone skin on this page, as its 5X Ceramide Barrier Moisture Gel and All Day Light Sunscreen Mist achieve High or Average fit levels for acne-prone skin, whereas Sesderma's Azelac RU Serum is only High. Skintific products on this page list no fragrance.

How do the founding years and company ownerships of Skintific and Sesderma compare?

Skintific was founded recently in 2021 and is owned by Guangzhou Feimei Network Technology Co., Ltd., whereas Sesderma was founded much earlier in 1989 in Spain and is owned by Grupo Sesderma.

Which brand has more products listed on the page that contain no fragrance?

Skintific has more products listed on the page with no fragrance, as every product on its page lists no fragrance in its ingredients compared to Sesderma.

What is the Lovi fit level of Sesderma's Azelac RU Serum for dry skin compared to Skintific's MATE FIT serum?

Sesderma's Azelac RU Serum has a Low Lovi fit for dry skin, while Skintific's MATE FIT serum also has a Caution fit level for dry skin.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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