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Skintific vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Skintific and Sesderma are thoughtful skincare brands offering targeted moisturizers, protective sunscreens, and advanced serums. The former is loved for its comforting preparations, such as the All Day Light Sunscreen Mist, 5X Ceramide Barrier Moisture Gel, and MUGWORT, which suit dry, dry sensitive, and acne-prone skin best. Meanwhile, the Spanish brand founded in 1989 and owned by Grupo Sesderma since 2026 is beloved for meticulously engineered formulas like the Azelac RU Serum, suiting sensitive, hyperpigmented, and aging skin types. Both brands differ because the former carefully balances every component for reliable daily care, while its counterpart relies on botanical extracts and active compounds to refine skin texture and promote a radiant complexion.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Skintific and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Skintific vs Sesderma products

Questions and answers

Skintific or Sesderma: which is better?

Skintific is a better fit for dry skin, dry sensitive skin, and acne-prone skin, with Lovi fit levels reaching High across several products on this page. Sesderma features fragrance in its products on this page, whereas every product on this page from Skintific lists no fragrance.

What is the difference between Skintific and Sesderma?

Skintific is a newer brand founded in 2021 that offers fragrance-free products on this page best fitting dry, dry sensitive, and acne-prone skin, while Sesderma is a Spanish brand founded in 1989 whose Azelac RU Serum contains fragrance. Niacinamide helps reduce cutaneous pigmentation and suppresses melanosome transfer.

The British Journal of Dermatology, 2002

Which is more affordable, Skintific or Sesderma?

This page does not provide pricing information to compare the affordability of Skintific and Sesderma.

Which causes fewer breakouts, Skintific or Sesderma?

Skintific is a better fit for acne-prone skin on this page, achieving a High fit for multiple products, whereas Sesderma's Azelac RU Serum achieves an average fit for oily acne-prone skin. Additionally, all products on the Skintific page list no fragrance, which helps reduce the risk of irritation.

How do the founding years and countries of origin compare between Skintific and Sesderma?

Skintific was founded in 2021 with its country of origin not specified, whereas Sesderma was founded in 1989 in Spain.

Which brand has more products that are formulated without fragrance?

Skintific has more products on this page formulated without fragrance, as every product from the brand lists no fragrance in its ingredients, whereas the Sesderma product includes fragrance.

Which brand offers a designated routine specifically for dry skin?

Skintific offers a designated routine specifically for dry skin, whereas the products on this page for Sesderma do not feature one. Lovi rates Skintific's fit for dry skin as high.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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