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Best serums and treatments for dry sensitive skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

What makes a good serum for dry sensitive skin

Serums with hyaluronic acid and glycerin help deeply hydrate dry skin and combat flakiness, while treatments with centella asiatica extract, madecassoside, and panthenol help soothe sensitivity and calm redness.

Journal of Cosmetic Dermatology, 2025

Products are ranked for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For a ranking based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Lovi's ranking

Why we picked these. Hyaluronic acid and niacinamide lock in moisture to relieve dryness and flakiness while soothing redness and irritation.

  1. 1
    Peach & Lily Glass Skin Refining Serum SuperiorAmazonS$63.44

    Why we picked it. This treatment will deeply hydrate your dry skin, thanks to ingredients like Sodium Hyaluronate and Beta-Glucan, while also soothing sensitivity.

  2. 2
    NEOGEN Dermalogy Real Vitamin C Serum HighAmazonS$50.41

    Why we picked it. This treatment will help you combat dryness and flakiness by providing intense hydration with ingredients like Sodium Hyaluronate and Glycerin, while also brightening your complexion.

  3. 3
    celimax The Real Cica Calming Ampoule HighAmazonS$45.67

    Why we picked it. This treatment will deeply hydrate and calm your dry skin, thanks to ingredients like Centella Asiatica Extract and Panthenol, providing exceptional performance in soothing and improving moisture levels.

  4. 4
    d'Alba Piedmont White Truffle Serum HighAmazonS$25.94

    Why we picked it. This treatment will deeply hydrate and calm your dry skin, thanks to ingredients like Glycerin and Sodium Hyaluronate, which are excellent humectants.

  5. 5
    ma:nyo Bifida Biome Complex Ampoule HighAmazonS$40.09
  6. 6
    Isntree C-Niacin Toning Ampoule HighAmazonS$32.85
  7. 7
    Bonajour Extreme Spot Serum HighAmazonS$41.48
  8. 8
    Isntree TW-Real Bifida Ampoule HighAmazonS$28.38
  9. 9
    Manyo Factory Bifida Biome Complex Ampoule HighAmazonS$40.09
  10. 10
    Olay Vitamin C + Peptide 24 Brightening Serum HighAmazonS$35.15
Where it goes in the routine: the full routine for dry sensitive skin

More serums rated for dry sensitive skin

Behind this ranking

Lovi ranks every product by its fit score, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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